The review presents the modern view on bronchioloalveolar carcinoma. The most attention is paid to the CT as one of the most important methods of primary diagnosis. Authors showed distinctive features of diseases that have similar X-ray picture.

Full Text



  1. Regnard, JF, Santelmo, N, Romdhani, N, et al. Bronchioloalveolar lung carcinoma: results of surgical treatment and prognostic factors. Chest 1998;114: 45-50.
  2. Bonomo, L, Storto, ML, Ciccotosto, C, et al. Bronchioloalveolar carcinoma of the lung. Eur Radiol 1998; 8: 996-1001.
  3. Харченко В.П., Галил-Оглы Г.А., Кузьмин И.В. Аденокарциномы. Онкоморфология легких. М., 1994; С. 52-62.
  4. Read WL, Page NC, Tierney RM, et al. The epidemiology of bronchioloalveolar carcinoma over the past two decades: Analysis of the SEER database. Lung Cancer 2004; 45:137-142.
  5. Malassez L. Examen histologique d'un cas de cancer encephaloide du poumon (epithelioma). Arch Physiol Norm Pathol 1876; 3: 353-372.
  6. Musser JH. Primary cancer of the lung. Univ Penn Bull 1903;16: 289-296.
  7. Storey CF, Knudtson KP, Lawrence BJ. Bronchiolar (alveolar. cell) carcinoma of the lung. J Thorac Cardiovasc Surg 1953; 26: 331-406.
  8. Liebow AA. Bronchiolo-alveolar carcinoma. Adv Intern Med. 1960;10:329-58
  9. Travis W.D., Colby T.V., Corrin B., et al. Histological Typing of Lung and Pleural Tumours. 3-rd Ed. Geneva: World Health Organization, 1999.
  10. Clayton F. The spectrum and significance of bronchioloalveolar carcinomas. Pathol Annu 1988; 23: 2: 361-94.
  11. Галил-Оглы Г.А., Харченко В.П., Гуревич Л.А., Бершанская А.М. Бронхиолоальвеолярный рак легкого. Арх пат 1995; 5: 64-70.
  12. Barcley J.E., Green M.R. Bronchioloalveolar carcinoma. J Clin Pathol 1996; 14: 8: 2377-86.
  13. Read WL, Page NC, Tierney RM, et al. The epidemiology of bronchioloalveolar carcinoma over the past two decades: Analysis of the SEER database. Lung Cancer 2004; 45:137-142.
  14. Travis WD, Muller-Hermelink H-K, Harris CC, Brambilla E. Pathology and Genetics of Tumours of the Lung, Pleura, Thymus and Heart. Lyon, France: IARC Press; 2004. World Health Organization Classification of Tumours.
  15. Трахтенберг А.Х., Чиссов В.И. Клиническая онкопульмонология. М., 2000. 600 с.
  16. Travis WD, Garg K, Franklin WA, et al. Evolving concepts in the pathology and computed tomography imaging of lung adenocarcinoma and bronchioloalveolar carcinoma. J Clin Oncol. 2005; 23: 3279-87.
  17. Ищенко Б.И., Бисенков Л.Н., Тюрин И.Е. Лучевая диагностика для торакальных хирургов. СПб., 2001.
  18. Lee HY, Lee KS, Han J, et al. Mucinous versus nonmucinous solitary pulmonary nodular bronchioloalveolar carcinoma: CT and FDG PET findings and pathologic comparisons. Lung Cancer 2009; 65: 170-175.
  19. Min JH, Lee HY, Lee KS, et al. Stepwise evolution from a focal pure pulmonary ground-glass opacity nodule into an invasive lung adenocarcinoma: an observation for more than 10 years. Lung Cancer. 2010; 69: 123-6.
  20. Patsios D, Roberts HC, Paul NS, et al. Pictorial review of the many faces of bronchioloalveolar cell carcinoma. Br J Radiol. 2007 Dec; 80(960): 1015-23.
  21. Park CM, Goo JM, Lee HJ. CT findings of atypical adenomatous hyperplasia in the lung. Korean J Radiol. 2006 Apr-Jun;7(2):80-6.
  22. Oda S, Awai K, Liu D,et al. Ground-glass opacities on thin-section helical CT: differentiation between bronchioloalveolar carcinoma and atypical adenomatous hyperplasia. Am J Roentgenol. 2008 May; 190(5): 1363-8.
  23. The Japanese Society of CT Screening. The management of patients with GGO.
  24. Cottin V, Cordier JF. Cryptogenic organizing pneumonia. Semin Respir Crit Care Med. 2012 Oct; 33(5): 462-75.
  25. Maldonado F, Daniels CE, Hoffman EA. Focal organizing pneumonia on surgical lung biopsy: causes, clinicoradiologic features, and outcomes. Chest 2007 Nov; 132(5): 1579-83.
  26. Kligerman SJ, Groshong S, Brown KK, et al. Nonspecific interstitial pneumonia: radiologic, clinical, and pathologic considerations. Radiographics. 2009; 29: 73-87.
  27. Martinez F, Chung JH, Digumarthy SR, et al. Common and uncommon manifestations of Wegener granulomatosis at chest CT: radiologic-pathologic correlation. Radiographics. 2012 Jan-Feb;32(1):51-69.
  28. Ananthakrishnan L, Sharma N, Kanne JP. Wegener's granulomatosis in the chest: high-resolution CT findings. Am J Roentgenol 2009;192(3): 676-682.
  29. Gaffo AL. Diagnostic approach to ANCA-associated vasculitides. Rheum Dis Clin North Am 2010; 36 (3):491-506.
  30. Kuhlman JE. Imaging pulmonary disease in AIDS: state of the art. Eur Radiol 1999;9(3):395-408.
  31. Marchiori E, Zanetti G, Escuissato DL, et al. Reversed halo sign: high-resolution CT scan findings in 79 patients. Chest 2012 May;141(5):1260-6.
  32. Ishii H, Trapnell B, Tazawa R, et al. Comparative Study of High-Resolution CT Findings Between Autoimmune and Secondary Pulmonary Alveolar Proteinosis. CHEST 2009; 136(5):1348-55.
  33. Travis WD, Brambilla E, Noguchi M, et al. IASLC/ATS/ERS International Multidisciplinary Classification of Lung Adenocarcinoma. J Thorac Oncol 2011; 6: 244-285.
  34. Watanabe S, Watanabe T, Arai K, et al. Results of wedge resection for focal bronchioloalveolar carcinoma showing pure ground-glass attenuation on computed tomography. Ann Thorac Surg 2002; 73: 1071- 1075.
  35. Sakurai H, Dobashi Y, Mizutani E, et al. Bronchioloalveolar carcinoma of the lung 3 centimeters or less in diameter: a prognostic assessment. Ann Thorac Surg 2004; 78: 1728-1733.
  36. Vazquez M, Carter D, Brambilla E, et al. Solitary and multiple resected adenocarcinomas after CT screening for lung cancer: histopathologic features and their prognostic implications. Lung Cancer 2009; 64: 148-154.
  37. Yamato Y, Tsuchida M, Watanabe T, et al. Early results of a prospective study of limited resection for bronchioloalveolar adenocarcinoma of the lung. Ann Thorac Surg 2001;71:971-974.
  38. Borczuk AC, Qian F, Kazeros A, et al. Invasive size is an independent predictor of survival in pulmonary adenocarcinoma. Am J Surg Pathol 2009; 33: 462-469.
  39. Yim J, Zhu LC, Chiriboga L, et al. Histologic features are important prognostic indicators in early stages lung adenocarcinomas. Mod Pathol 2007; 20: 233-241.
  40. Goldstraw P. IASLC Staging Manual in Thoracic Oncology. Orange Park, FL: International Association for the Study of Lung Cancer, Editorial Rx Press, 2009.
  41. Goldstraw P, Crowley J, Chansky K, et al. The IASLC Lung Cancer Staging Project: proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM Classification of malignant tumours. J Thorac Oncol 2007; 2: 706 -714.

Copyright (c) 2013 Urazovsky N.Y., Averyanov A.V., Lesnyak V.N.

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies