Ecological geneticsEcological geneticsЭкологическая генетика1811-09322411-9202Eco-Vector1058810.17816/ecogen17133-41Genetic basis of ecosystems evolutionГенетические основы эволюции экосистемResearch ArticleThe role of universal regulators of plant growth and development the DELLA proteins in the control of symbiosisРоль универсальных регуляторов роста и развития растений DELLA-белков в контроле симбиозовhttps://orcid.org/0000-0003-1845-9701DolgikhAleksandra V.ДолгихАлександра Вячеславовна
Russian Federation

Student, Laboratory of Molecular and Cellular Biology

студент, лаборатория молекулярной и клеточной биологии

sqshadol@gmail.comhttps://orcid.org/0000-0002-5375-09436603496335G-6363-20174453-2060DolgikhElena A.ДолгихЕлена Анатольевна
Russian Federation

Doctor of Science, Group Leader, Laboratory of Molecular and Cellular Biology

д-р биол. наук, ведущий научный сотрудник лаборатории молекулярной и клеточной биологии

dol2helen@yahoo.comAll-Russia Research Institute for Agricultural MicrobiologyФГБНУ «Всероссийский научно-исследовательский институт сельскохозяйственной микробиологии»180220191503201917133412911201818022019Copyright ©; 2019, Dolgikh A.V., Dolgikh E.A.Copyright ©; 2019, Долгих А.В., Долгих Е.А.2019Dolgikh A.V., Dolgikh E.A.Долгих А.В., Долгих Е.А.http://creativecommons.org/licenses/by/4.0https://journals.eco-vector.com/ecolgenet/article/view/10588

The regulators of the gibberellin response, the DELLA proteins, are universal participants of signaling pathways that coordinate the processes of plant growth and development. This regulation is provided by the integration of external effect, as well as internal signals, such as a level of phytohormones and secondary messengers. Since DELLA proteins are extremely sensitive to increasing or decreasing of the gibberellic acid (GA) endogenous level, their direct interaction with transcription factors modulates the activity of the latter, and, consequently, the level of expression of target genes in response to external signals causing changes in the level of GA. However, the molecular mechanisms of the effect of DELLA proteins on the development of symbiosis remain poorly understood. The review analyzes classical and modern data on the functioning of DELLA proteins in plants.

Универсальными участниками сигнальных путей, координирующими процессы роста и развития растений, являются регуляторы гиббереллинового ответа DELLA-белки. Эта регуляция обеспечивается путем интеграции внешних воздействий, а также внутренних сигналов, таких как изменение в уровне фитогормонов и вторичных мессенджеров. Поскольку DELLA-белки чрезвычайно чувствительны к повышению или же снижению эндогенного уровня гибберелловой кислоты (ГК), их прямое взаимодействие с транскрипционными факторами модулирует активность последних, а следовательно, и уровень экспрессии генов-мишеней в ответ на внешние воздействия, вызывающие изменения в уровне ГК. Одна из наиболее важных функций, которые выполняют DELLA-белки, связана с их участием в регуляции развития симбиозов растений с азотфиксирующими клубеньковыми бактериями и грибами арбускулярной микоризы. Однако молекулярные механизмы влияния DELLA-белков на развитие симбиозов остаются малоизученными. В обзоре проведен анализ классических и современных данных о функционировании DELLA-белков у растений.

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