Ecological geneticsEcological geneticsЭкологическая генетика1811-09322411-9202Eco-Vector542410.17816/ecogen443-9ArticlesСтатьиResearch ArticleRole Of WOX And KNOX Transcription Factors In Plant Development And Tumor FormationРОЛЬ ТРАНСКРИПЦИОННЫХ ФАКТОРОВ WOX И KNOX В РАЗВИТИИ И ОПУХОЛЕОБРАЗОВАНИИ У РАСТЕНИЙOsipovaMaria AОсиповаМария Александровнаmary_osipova@mail.ruDolgikhElena AДолгихЕлена Анатольевнаdol2helen@yahoo.comLutovaLudmila AЛутоваЛюдмила Алексеевнаolgunja_@mail.ruSaint Petersburg State University, Saint-Petersburg, RFСанкт-Петербургский государственный университет, Санкт-Петербург, РФAll-Russia Research Institute for Agricultural Microbiology, St. Petersburg, RFВсероссийский научно-исследовательский институт сельскохозяйственной микробиологии, Санкт-Петербург, РФSaint-Petersburg State University., Saint-Petersburg, RFСанкт-Петербургский государственный университет, Санкт-Петербург, РФ1512200644VOL 4, NO4 (2006)ТОМ 4, №4 (2006)3914112016Copyright ©; 2006, Osipova M.A., Dolgikh E.A., Lutova L.A.Copyright ©; 2006, Осипова М.А., Долгих Е.А., Лутова Л.А.2006Osipova M.A., Dolgikh E.A., Lutova L.A.Осипова М.А., Долгих Е.А., Лутова Л.А.http://creativecommons.org/licenses/by/4.0https://journals.eco-vector.com/ecolgenet/article/view/5424

Homeodomain-containing transcription factors are the important regulators of multicellular organism's development. Plant transcription factors WOX and KNOX play the key role in meristem maintenance, controlling cell proliferation and preventing differentiation. The precise mechanism of WOX and KNOX action hasn't been well studied, however these transcription factors were shown to play the important role in plant hormones homeostasis, cytokinins in particular. Plant transcription factors of KNOX group demonstrate the similarities in structure and are supposed have the common origin with animal transcription factors of MEIS group. This review describes WOX and KNOX transcription factor families, their interaction with plant hormones. The role of homeodomain-containing transcription factors in plant and animal tumor formation is discussed.

Гомеодомен-содержащие транскрипционные факторы являются важными регуляторами развития многоклеточных организмов. транскрипционные факторы растений WOX и KNOX играют ключевую роль в поддержании активности меристем, регулируют пролиферацию и предотвращают дифференцировку клеток растений. Конкретный механизм их действия на настоящий момент до конца не изучен, однако показано, что они оказывают влияние на метаболизм фитогормонов, в частности, цитокинина. Транскрипционные факторы растений группы KNOX обнаруживают сходство по структуре и, как предполагается, имеют общее происхождение с транскрипционными факторами животных группы MEIS. В обзоре представлена характеристика транскрипционных факторов семейств WOX и KNOX, их взаимодействие с гормональной системой растений. Обсуждается роль гомеодомен-содержащих транскрипционных факторов в формировании опухолей у животных и у растений. Работа поддержана грантами NWO 06-04-89000НВОЦ-а, CRDF ST-012-0, CRDF-Мин. Обр. RUXO-012ST-06 (BP2M12), CRDF Y2-B12-05, HШ-9744.2006.4, РФФИ 05-04-48583, РФФИ 05-04-49105а.<img src="http://elibrary.ru/pic/1pix.gif" />

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