В настоящей статье описаны основные принципы работы технологии непрерывной покадровой съемки, или технологии TIME-LAPSE. Обозначено место данной технологии в современной эмбриологической практике, проведено сравнение с традиционной системой культивирования. Представлен обзор современных инкубаторов, оснащенных системой TIME-LAPSE, в том числе отечественного производства, перечислены их преимущества и недостатки. Рассмотрены основные этапы раннего эмбрионального развития человека, отмечены редкие события, например, такие, как аномальное образование и исчезновение пронуклеусов, многоядерность бластомеров, обратное дробление, «прямое дробление» на три бластомера, которые можно визуализировать только с применением технологии TIME-LAPSE, но не при традиционной визуальной оценке морфологии эмбриона. Уделено внимание использованию искусственного интеллекта совместно с технологией TIME-LAPSE для объективной оценки и ранжирования эмбрионов согласно их морфокинетическим характеристикам. В заключение представлены данные о влиянии технологии на результативность программ экстракорпорального оплодотворения. Более того, приведены такие неочевидные преимущества данной системы, как возможность обучения и передачи видеоданных между участниками протокола экстракорпорального оплодотворения.

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