Journal of obstetrics and women's diseasesJournal of obstetrics and women's diseases1684-04611683-9366Eco-Vector8748010.17816/JOWD87480Review ArticleThe experience of genital prolapse treatment and urine incontinence using synthetic materialsKrasnopolskiyV. I.info@eco-vector.comBuyanovaS. N.info@eco-vector.comPetrovaV. D.info@eco-vector.comMuravyevaТ. G.info@eco-vector.comEvsyukovaL. V.info@eco-vector.comPutilovskiyМ. А.info@eco-vector.comMoscow Regional Scientific Research Institute of Obstetrics and Gynecology15112005545S68691511200510112021Copyright © 2005, Eсо-Vector2005<p><strong>Background: </strong>genital prolaps which developes especially in young unipara women after noncomplicated delivery without hormonal disorders and factors provided intraabdominal pressure increasing is a common manifestation of generalized connective tissue defect (CTD) on the level of reproductive system.</p>treating genital prolapsestress urinary incontinencethe use of synthetic materials in surgerysurgical gynecologyлечения пролапса гениталийнедержания мочи при напряженииприменение синтетических материалов в хирургиихирургическая гинекология<p><strong>Background: </strong>genital prolaps which developes especially in young unipara women after noncomplicated delivery without hormonal disorders and factors provided intraabdominal pressure increasing is a common manifestation of generalized connective tissue defect (CTD) on the level of reproductive system. The Ist and IIId types of collagen define mechanical structure of ligaments. The immunohistochemical investigations in cases of CTD showed sufficient expression of the Ist and IIId types of collagen but they did not form typical dimensional structure and were replaced of IVth type of collagen that led to altered mechanical characteristics of ligaments.</p>
<p><strong>Materials and methods. </strong>The method of surgery in patients with altered uterine fixation was aimed on liquidation of uterine prolapse and prevention of its further reccurence. The basic surgery - hysterectomy- was added of vaginopexy with prolen transplantant (Gyne Mesh or Gyne Mesh soft). At 13,5% of patients with CTD MESH - vaginopexy was performed as the basic surgery. Also vaginal hysterectomy, anterior vaginl plastics using synthetic materials, TVT or TVT-0 and other surgeries were made. 10 patients with CTD desired to save the reproductive function underwent nonradical surgery.</p>
<p><strong>Results. </strong>The using of synthetic materials in patients with CTD is rational because of insufficiency of their own tissues, development of severe genital prolapse and high risk of reccurence.</p>