Journal of obstetrics and women's diseasesJournal of obstetrics and women's diseases1684-04611683-9366Eco-Vector8953610.17816/JOWD89536Research ArticleThe state of estrogen-dependent organs of women with surgical menopause and hormone replacement therapySerebrennikovaK. G.info@eco-vector.comChumakovaN. V.info@eco-vector.comKonevМ. V.info@eco-vector.comIzhevsk State Medical Academy3004200150294990112202101122021Copyright © 2021, Eсо-Vector2021<p>The research aims at studying the dynamics and character o f disorders in the target-organs and appraisingthe quality оf life in women with surgical menopause (SM ) on the background o f hormonal replacement therapy (HRT).<br />Application o f Femoston as the preferable preparation was determined by functional state оf estrogen-dependent organs (cardiovascular system, bone tissue, and mamma) and accompanying extragenital diseases.<br />Hormonal replacement therapy effectively reduces early climacterics disorders connected with menopause and promotes prophylaxis o f late complications o f menopause development (cardiovascular disease and osteoporosis). Femoston is the preparation o f choice fo r women with surgical menopause as it exerts minimum influence on the metabolism and doesnt have anabolic or glucocorticoid effects.</p>estrogen-dependent organs in womenmenopausal symptom complexclimactericэстрогензависимые органы у женщинменопаузальный симптомокомплексклимактерия