Abstract
In the author's opinion skin and tongue keloidosis, chalikosis and antrakochalikosis of lungs and callous ulcer of stomach are manifestations of the same peculiar connective tissue disease, to which S. gives the name of keloidosis. The essence of this disease consists in development of granulation tissue rich in fibroblasts, but poor in blood vessels, which then forms hyaline nodules ("nodose keloidosis"), or hyaline bands ("diffuse keloidosis"). The cause of keloidosis lies in any irritations of the physical and chemical nature; but in addition to this a congenital predisposition of the connective tissue is also necessary for the development of this disease.