Heart rate variability as an indicator of autonomic tone in ent diseases and errors in assessing its parameters


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Abstract

In laryngology, heart rate variability (HRV) is a reliable, non-invasive marker of the activity of the autonomic nervous system. To assess parasympathetic tone, the high-frequency component (HF) of HRV is most often used, the main part of which is respiratory sinus arrhythmia (DSA). The paper analyzes the errors of 4 methods for assessing the amplitude of the DSA and fluctuations in the HF range: methods for calculating SDNN and RMSSD indicators, a method based on an estimate of the average spectral density in the respiratory range, and the method of cross-correlation coefficients. The analysis used 35 records (18 young and 17 elderly subjects) from the Fantasia Physio Bank database. It is shown that the errors of the RMSSD indicator 1) when assessing the amplitude of the HF range oscillations are on average ~ 16% for the sample for the young and ~ 19% for the elderly; 2) when assessing DSA, they lie in the range from 12% to 64% with an average value for the sample of 38–16% for young subjects, and in the range from 26% to 215% with an average value for the sample of 76-48%. The reasons for the RMSSD errors are the presence of low-frequency oscillations and oscillations with a frequency exceeding 0.4 Hz in the series of the first differences of the RR-intervals. The considered spectral method and the method based on the calculation of the correlation coefficient require simultaneous recording of the ECG and respiration. The error of the spectral method is about 3% at an HRV power of 4000 ms2 and about 12% at an HRV power of 440 ms2. The correlation analysis method evaluates DSA with an error ranging from 2.5% to 4%, depending on the relationship between HRV and respiration; The advantage of the method is the use of only the time domain — the method does not require the construction of spectral densities, the transition to which causes a lot of controversy due to the unevenness of a number of RR-intervals

About the authors

Victor M. Bahilin

Saint Petersburg Institute of Ear Throat, Nose and Speech,

Author for correspondence.
Email: sc.victor.6219@gmail.com
ORCID iD: 0000-0002-0116-9890
SPIN-code: 3931-8067

научный сотрудник лаборато­рии информатики и статистики 

Russia, Saint Petersburg, Bronnitsraia str. 9

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