Ophthalmology ReportsOphthalmology Reports1998-71022412-5423Eco-Vector11181110.17816/OV111811Research ArticleManifestations of uveitis of toxoplasmosis etiology after vaccination: clinical casesIonovaOksana G.<p>Cand. Sci. (Med.), Ophthalmologist of the Department of Phthisioophthalmology</p>glazniif@mail.ruKaretskyAndrey V.<p>Cand. Sci. (Med.), Head of the Department of Phthisiophthalmology</p>glazniif@mail.ruHokkanenValentina M.<p>Dr. Sci. (Med.), Professor, Professor of Ophthalmology Department</p>hokkanen@bk.ruZumbulidzeNataliya G.<p>Cand. Sci. (Med.), Assistant Professor of Ophthalmology Department</p>guramovna@gmail.comBagriantsevaOksana V.<p>Ophthalmologist</p>medinfo@mc21.ruSt. Petersburg Research Institute of PhthisiopulmonologyNorth-Western State Medical University named after I.I. MechnikovMedical Center “XXI century”2002202315485911110202226122022Copyright © 2023, ECO-vector LLC2023<p>Inflammatory diseases of the retina and choroid (chorioretinitis), including those of toxoplasmosis etiology usually occur against a background of decrease in immunity. We present two clinical cases of ocular inflammation at different times after the vaccination with Sputnik V. An analysis of the occurrence of ocular pathologic condition after vaccination to prevent coronavirus infection caused by the SARS-CoV-2 virus will help determine the criteria for prophylactic ophthalmological examination of patients before vaccination.</p>chorioretinitisuveitistoxoplasmosisinflammationvaccinecoronavirus infectionOCTneuroepitheliumpigment epitheliumхориоретинитувеиткоронавирусная инфекциятоксоплазмозвоспалениевакцинаОКТнейроэпителийпигментный эпителий[Avetisov SEh, Egorov EA, Moshetova LK, et al, editors. Oftal’mologiya: natsional’noe rukovodstvo. 2nd edition. Moscow: GEHOTAR-Media, 2008. P. 506–507. (In Russ.)][Kanski DzhDzh, Milevski StA, Damato BEh, Tehnner V. Zabolevaniya glaznogo dna. Avetisov SEh, editor. Moscow: MEDpress-inform, 2009. P. 171–176. (In Russ.)][Nasiri N, Sharifi H, Bazrafshan A, et al. Ocular manifestations of COVID-19: a systematic review and meta-analysis. J Ophthalmic Vis Res. 2021;16(1):103–112. DOI: 10.18502/jovr.v16i1.8256][Maychuk DYu, Atlas SN, Loshkareva AO. Ocular manifestations of coronavirus infection COVID-19 (clinical observation). Vestnik Oftalmologii. 2020;136(4):118123. (In Russ.) DOI: 10.17116/oftalma2020136041118][Hwang JH. Uveitis after COVID-19 Vaccination. Case Rep Ophthalmol. 2022;13:124–127. DOI: 10.1159/000521785][Benage M, Fraunfelder FW. Vaccine-associated uveitis. MO Med. 2016;113:48–52.][Cunningham ET Jr, Moorthy RS, Fraunfelder FW, Zierhut M. Vaccine-associated uveitis. Ocul Immunol Inflamm. 2019;27(4):517–520. DOI: 10.1080/09273948.2019.1626188]