<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE root>
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Ophthalmology Reports</journal-id><journal-title-group><journal-title xml:lang="en">Ophthalmology Reports</journal-title><trans-title-group xml:lang="ru"><trans-title>Офтальмологические ведомости</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1998-7102</issn><issn publication-format="electronic">2412-5423</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">119918</article-id><article-id pub-id-type="doi">10.17816/OV119918</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Case reports</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Клинические случаи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Myelinated retinal nerve fibers associated with retinal vascular abnormalities and retino-vitreal neovascularization complicated by recurrent vitreous hemorrhage (clinical case)</article-title><trans-title-group xml:lang="ru"><trans-title>Миелиновые волокна сетчатки, ассоциированные с ретинальными сосудистыми аномалиями и ретиновитреальной неоваскуляризацией, осложнённой рецидивирующим гемофтальмом (клинический случай)</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title/></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8191-6090</contrib-id><name-alternatives><name xml:lang="en"><surname>Panfilova</surname><given-names>Anastasiya N.</given-names></name><name xml:lang="ru"><surname>Панфилова</surname><given-names>Анастасия Николаевна</given-names></name><name xml:lang="zh"><surname></surname><given-names></given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>ophthalmologist</p></bio><bio xml:lang="ru"><p>врач-офтальмолог</p></bio><email>panfilova@zrenie.spb.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2162-4018</contrib-id><contrib-id contrib-id-type="spin">8921-9738</contrib-id><name-alternatives><name xml:lang="en"><surname>Doktorova</surname><given-names>Taisiia A.</given-names></name><name xml:lang="ru"><surname>Докторова</surname><given-names>Таисия Александровна</given-names></name><name xml:lang="zh"><surname></surname><given-names></given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>postgraduate student, ophthalmologis</p></bio><bio xml:lang="ru"><p>аспирант, врач-офтальмолог</p></bio><email>taisiiadok@mail.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8670-2964</contrib-id><contrib-id contrib-id-type="spin">4286-6100</contrib-id><name-alternatives><name xml:lang="en"><surname>Suetov</surname><given-names>Aleksei A.</given-names></name><name xml:lang="ru"><surname>Суетов</surname><given-names>Алексей Александрович</given-names></name><name xml:lang="zh"><surname></surname><given-names></given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>МD, Cand. Sci. (Med.), ophthalmologist, senior research associate</p></bio><bio xml:lang="ru"><p>канд. мед. наук, врач-офтальмолог, ст. научн. сотр.</p></bio><email>ophtalm@mail.ru</email><xref ref-type="aff" rid="aff4"/><xref ref-type="aff" rid="aff5"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Ophthalmological center “Vision”</institution></aff><aff><institution xml:lang="ru">Офтальмологический центр «Зрение»</institution></aff><aff><institution xml:lang="zh"></institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">S. Fyodorov Eye Microsurgery Federal State Institution, Saint Petersburg Branch</institution></aff><aff><institution xml:lang="ru">Санкт-Петербургский филиал Национального медицинского исследовательского центра «Межотраслевой научно-технический комплекс «Микрохирургия глаза» им. акад. С.Н. Фёдорова»</institution></aff><aff><institution xml:lang="zh"></institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">North-Western State Medical University named after I.I. Mechnikov</institution></aff><aff><institution xml:lang="ru">Северо-Западный государственный медицинский университет им. И.И. Мечникова</institution></aff><aff><institution xml:lang="zh"></institution></aff></aff-alternatives><aff-alternatives id="aff4"><aff><institution xml:lang="en">S. Fyodorov Eye Microsurgery Federal State Institution, Saint Petersburg Branch</institution></aff><aff><institution xml:lang="ru">Санкт-Петербургский филиал Национального медицинского исследовательского центра «Межотраслевой научно-технический комплекс «Микрохирургия глаза» им. акад. С.Н. Фёдорова»</institution></aff></aff-alternatives><aff-alternatives id="aff5"><aff><institution xml:lang="en">State Scientific Research Test Institute of Military Medicine</institution></aff><aff><institution xml:lang="ru">Государственный научно-исследовательский испытательный институт военной медицины</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2023-07-14" publication-format="electronic"><day>14</day><month>07</month><year>2023</year></pub-date><volume>16</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><issue-title xml:lang="zh"/><fpage>91</fpage><lpage>97</lpage><history><date date-type="received" iso-8601-date="2022-12-24"><day>24</day><month>12</month><year>2022</year></date><date date-type="accepted" iso-8601-date="2023-02-23"><day>23</day><month>02</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2023, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2023, Эко-Вектор</copyright-statement><copyright-statement xml:lang="zh">Copyright ©; 2023,</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">Эко-Вектор</copyright-holder></permissions><self-uri xlink:href="https://journals.eco-vector.com/ov/article/view/119918">https://journals.eco-vector.com/ov/article/view/119918</self-uri><abstract xml:lang="en"><p>Myelinated retinal nerve fibres are a rare, benign and asymptomatic lesion that is detected incidentally at fundus examination. In some cases, they may be associated with various abnormalities of the eye or have a complicated course. The article presents a clinical case of myelinated retinal nerve fibers associated with retinal vascular abnormalities and retino-vitreal neovascularization complicated by recurrent vitreous hemorrhage.</p></abstract><trans-abstract xml:lang="ru"><p>Миелиновые волокна сетчатки — редкое доброкачественное и бессимптомное образование, выявляемое случайно при осмотре глазного дна. В отдельных случаях они могут быть ассоциированы с различными аномалиями органа зрения или иметь осложнённое течение. В статье представлен клинический случай обнаружения миелиновых волокон сетчатки, ассоциированных с ретинальными сосудистыми аномалиями и ретиновитреальной неоваскуляризацией, осложнённой рецидивирующим гемофтальмом.</p></trans-abstract><trans-abstract xml:lang="zh"><p/></trans-abstract><kwd-group xml:lang="en"><kwd>myelinated nerve fibers</kwd><kwd>retinal abnormalities</kwd><kwd>vitreous hemorrhage</kwd><kwd>neovascularization</kwd><kwd>optical coherence tomography</kwd><kwd>fluorescein angiography</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>миелиновые волокна сетчатки</kwd><kwd>аномалии сетчатки</kwd><kwd>гемофтальм</kwd><kwd>неоваскуляризация</kwd><kwd>оптическая когерентная томография</kwd><kwd>флуоресцентная ангиография</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Shelton JB, Digre KB, Gilman J, et al. Characteristics of myelinated retinal nerve fiber layer in ophthalmic imaging: Findings on autofluorescence, fluorescein angiographic, infrared, optical coherence tomographic, and red-free images. Arch Ophthalmol. 2013;131(1):107–109. DOI: 10.1001/jamaophthalmol.2013.560</mixed-citation><mixed-citation xml:lang="ru">Shelton J.B., Digre K.B., Gilman J., et al. Characteristics of myelinated retinal nerve fiber layer in ophthalmic imaging: Findings on autofluorescence, fluorescein angiographic, infrared, optical coherence tomographic, and red-free images // Arch Ophthalmol. 2013. Vol. 131, No. 1. P. 107–109. DOI: 10.1001/jamaophthalmol.2013.560</mixed-citation></citation-alternatives></ref><ref id="B2"><label>2.</label><citation-alternatives><mixed-citation xml:lang="en">Straatsma BR, Foos RY, Heckenlively JR, Taylor GN. Myelinated retinal nerve fibers. Am J Ophthalmol. 1981;91(1):25–38. DOI: 10.1016/0002-9394(81)90345-7</mixed-citation><mixed-citation xml:lang="ru">Straatsma B.R., Foos R.Y., Heckenlively J.R., Taylor G.N. Myelinated retinal nerve fibers // Am J Ophthalmol. 1981. Vol. 91, No. 1. P. 25–38. DOI: 10.1016/0002-9394(81)90345-7</mixed-citation></citation-alternatives></ref><ref id="B3"><label>3.</label><citation-alternatives><mixed-citation xml:lang="en">Jean-Louis G, Katz BJ, Digre KB, et al. Acquired and progressive retinal nerve fiber layer myelination in an adolescent. Am J Ophthalmol. 2000;130(3):361–362. DOI: 10.1016/S0002-9394(00)00550-X</mixed-citation><mixed-citation xml:lang="ru">Jean-Louis G., Katz B.J., Digre K.B., et al. Acquired and progressive retinal nerve fiber layer myelination in an adolescent // Am J Ophthalmol. 2000. Vol. 130, No. 3. P. 361–362. DOI: 10.1016/S0002-9394(00)00550-X</mixed-citation></citation-alternatives></ref><ref id="B4"><label>4.</label><citation-alternatives><mixed-citation xml:lang="en">Ali BH, Logani S, Kozlov KL, et al. Progression of retinal nerve fiber myelination in childhood. Am J Ophthalmol. 1994;118(4):515–517. DOI: 10.1016/S0002-9394(14)75805-2</mixed-citation><mixed-citation xml:lang="ru">Ali B.H., Logani S., Kozlov K.L., et al. Progression of retinal nerve fiber myelination in childhood // Am J Ophthalmol. 1994. Vol. 118, No. 4. P. 515–517. DOI: 10.1016/S0002-9394(14)75805-2</mixed-citation></citation-alternatives></ref><ref id="B5"><label>5.</label><citation-alternatives><mixed-citation xml:lang="en">Fasiuddin KJ. Ocular findings associated with myelinated retinal nerve fibers. Cureus. 2021;13(4): e14552. DOI: 10.7759/cureus.14552</mixed-citation><mixed-citation xml:lang="ru">Fasiuddin K.J. Ocular findings associated with myelinated retinal nerve fibers // Cureus. 2021. Vol. 13, No. 4. ID e14552. DOI: 10.7759/cureus.14552</mixed-citation></citation-alternatives></ref><ref id="B6"><label>6.</label><citation-alternatives><mixed-citation xml:lang="en">Berry-Brincat A, Shafquat S. Myelinated nerve fibres: a rare cause of recurrent vitreous haemorrhage. Eye. 2008;22:165–167. DOI: 10.1038/sj.eye.6703002</mixed-citation><mixed-citation xml:lang="ru">Berry-Brincat A., Shafquat S. Myelinated nerve fibres: a rare cause of recurrent vitreous haemorrhage // Eye. 2008. Vol. 22. P. 165–167. DOI: 10.1038/sj.eye.6703002</mixed-citation></citation-alternatives></ref><ref id="B7"><label>7.</label><citation-alternatives><mixed-citation xml:lang="en">Hildebrand C, Remahl S, Persson H, Bjartmar C. Myelinated nerve fibres in the CNS. Prog Neurobiol. 1993;40(3):319–384. DOI: 10.1016/0301-0082(93)90015-K</mixed-citation><mixed-citation xml:lang="ru">Hildebrand C., Remahl S., Persson H., Bjartmar C. Myelinated nerve fibres in the CNS // Prog Neurobiol. 1993. Vol. 40, No. 3. P. 319–384. DOI: 10.1016/0301-0082(93)90015-K</mixed-citation></citation-alternatives></ref><ref id="B8"><label>8.</label><citation-alternatives><mixed-citation xml:lang="en">Hunter SF, Leavitt JA, Rodriguez M. Direct observation of myelination in vivo in the mature human central nervous system. A model for the behaviour of oligodendrocyte progenitors and their progeny. Brain. 1997;120(11):2071–2082. DOI: 10.1093/BRAIN/120.11.2071</mixed-citation><mixed-citation xml:lang="ru">Hunter S.F., Leavitt J.A., Rodriguez M. Direct observation of myelination in vivo in the mature human central nervous system. A model for the behaviour of oligodendrocyte progenitors and their progeny // Brain. 1997. Vol. 120, No. 11. P. 2071–2082. DOI: 10.1093/BRAIN/120.11.2071</mixed-citation></citation-alternatives></ref><ref id="B9"><label>9.</label><citation-alternatives><mixed-citation xml:lang="en">Fitzgibbon T, Nestorovski Z. Morphological consequences of myelination in the human retina. Exp Eye Res. 1997;65(6):809–819. DOI: 10.1006/exer.1997.0388</mixed-citation><mixed-citation xml:lang="ru">Fitzgibbon T., Nestorovski Z. Morphological consequences of myelination in the human retina // Exp Eye Res. 1997. Vol. 65, No. 6. P. 809–819. DOI: 10.1006/exer.1997.0388</mixed-citation></citation-alternatives></ref><ref id="B10"><label>10.</label><citation-alternatives><mixed-citation xml:lang="en">Tarabishy AB, Alexandrou TJ, Traboulsi EI. Syndrome of myelinated retinal nerve fibers, myopia, and amblyopia: a review. Surv Ophthalmol. 2007;52(6):588–596. DOI: 10.1016/j.survophthal.2007.08.016</mixed-citation><mixed-citation xml:lang="ru">Tarabishy A.B., Alexandrou T.J., Traboulsi E.I. Syndrome of myelinated retinal nerve fibers, myopia, and amblyopia: a review // Surv Ophthalmol. 2007. Vol. 52, No. 6. P. 588–596. DOI: 10.1016/j.survophthal.2007.08.016</mixed-citation></citation-alternatives></ref><ref id="B11"><label>11.</label><citation-alternatives><mixed-citation xml:lang="en">Silvestri G, Sehmi K, Hamilton P. Retinal vascular abnormalities. A rare complication of myelinated nerve fibers? Retina. 1996;16(3):214–218. DOI: 10.1097/00006982-199616030-00005</mixed-citation><mixed-citation xml:lang="ru">Silvestri G., Sehmi K., Hamilton P. Retinal vascular abnormalities. A rare complication of myelinated nerve fibers? // Retina. 1996. Vol. 16, No. 3. P. 214–218. DOI: 10.1097/00006982-199616030-00005</mixed-citation></citation-alternatives></ref><ref id="B12"><label>12.</label><citation-alternatives><mixed-citation xml:lang="en">Leys AM, Leys MJ, Hooymans JMM, et al. Myelinated nerve fibers and retinal vascular abnormalities. Retina. 1996;16(2):89–96. DOI: 1097/00006982-199616020-00001</mixed-citation><mixed-citation xml:lang="ru">Leys A.M., Leys M.J., Hooymans J.M.M., et al. Myelinated nerve fibers and retinal vascular abnormalities // Retina. 1996. Vol. 16, No. 2. P. 89–96. DOI: 1097/00006982-199616020-00001</mixed-citation></citation-alternatives></ref><ref id="B13"><label>13.</label><citation-alternatives><mixed-citation xml:lang="en">Minning CA, Davidorf FH. Neovascularization associated with myelinated nerve fibers: a case report. Ann Ophthalmol. 1983;15(12):1142–1144.</mixed-citation><mixed-citation xml:lang="ru">Minning C.A., Davidorf F.H. Neovascularization associated with myelinated nerve fibers: a case report // Ann Ophthalmol. 1983. Vol. 15, No. 12. P. 1142–1144.</mixed-citation></citation-alternatives></ref></ref-list></back></article>
