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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Ophthalmology Reports</journal-id><journal-title-group><journal-title xml:lang="en">Ophthalmology Reports</journal-title><trans-title-group xml:lang="ru"><trans-title>Офтальмологические ведомости</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1998-7102</issn><issn publication-format="electronic">2412-5423</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">439</article-id><article-id pub-id-type="doi">10.17816/OV2013135-43</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">The enzymatic vitreolysis — a new trend in the treatment of retinal vein occlusions</article-title><trans-title-group xml:lang="ru"><trans-title>Энзимный витреолизис — новое направлениев лечении окклюзий вен сетчатки</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Tultseva</surname><given-names>Svetlana Nikolaevna</given-names></name><name xml:lang="ru"><surname>Тульцева</surname><given-names>Светлана Николаевна</given-names></name></name-alternatives><bio xml:lang="en"><p>MD, assistant professor, Department of Ophthalmology</p></bio><bio xml:lang="ru"><p>к. м. н., доцент кафедры офтальмологии</p></bio><email>tultceva@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">I. P. Pavlov State Medical University</institution></aff><aff><institution xml:lang="ru">СПбГМУ им. акад. И. П. Павлова</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2013-03-15" publication-format="electronic"><day>15</day><month>03</month><year>2013</year></pub-date><volume>6</volume><issue>1</issue><issue-title xml:lang="en">VOL 6, NO1 (2013)</issue-title><issue-title xml:lang="ru">ТОМ 6, №1 (2013)</issue-title><fpage>35</fpage><lpage>43</lpage><history><date date-type="received" iso-8601-date="2015-06-24"><day>24</day><month>06</month><year>2015</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2013, Tultseva S.N.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2013, Тульцева С.Н.</copyright-statement><copyright-year>2013</copyright-year><copyright-holder xml:lang="en">Tultseva S.N.</copyright-holder><copyright-holder xml:lang="ru">Тульцева С.Н.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2015-06-08"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">http://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://journals.eco-vector.com/ov/article/view/439">https://journals.eco-vector.com/ov/article/view/439</self-uri><abstract xml:lang="en"><p>Vitreoretinal relationships exert a significant influence on the course of retinal vein occlusions (RVO) and post-thrombotic retinopathy. A single intravitreal injection of Actilyse 50 mkg in the period from 1 till 21 days from the disease onset stimulates a posterior vitreous detachment in 30.4% patients with non-ischemic and 24.8% patients with the type of ischemic RVO. The process of transition from the partial posterior hyaloid detachment to the complete one, and complete posterior hyaloid detachment in patients who did not have it from the beginning, was accompanied by a visual acuity increase by a factor of 1.5. The use of enzymatic vitreolysis in patients with RVO increases the probability of reduced macular edema in the early disease period, to increases visual acuity, and decreases the risk of neovascularization development in the posterior eyeball segment.</p></abstract><trans-abstract xml:lang="ru"><p>Витреоретинальные взаимоотношения оказывают значимое влияние на течение окклюзии вен сетчатки (ОВС) и посттромботической ретинопатии. Однократное интравитреальное введение 50 мкг препарата Актилизе в период с 1 по 21 сутки от начала заболевания позволяют стимулировать заднюю отслойку стекловидного тела у 30,4 % больных с неишемическим и 24,8 % больных с ишемическим типом ОВС. Процесс перехода частичной отслойки ЗГМ в полную, и полное отслоение ЗГМ у пациентов, изначально не имевших отслойки, сопровождался улучшением остроты зрения более чем в 1,5 раза. Использование энзимного витреолизиса в лечении ОВС позволяет увеличить шанс полной резорбции макулярного отека в раннем периоде заболевания, повысить остроту зрения, снизить риск развития неоваскулярнизации в заднем отрезке глазного яблока.</p></trans-abstract><kwd-group xml:lang="en"><kwd>retinal vein occlusion</kwd><kwd>retinal vein thrombosis</kwd><kwd>vitreolysis</kwd><kwd>vitreoretinal traction syndrome</kwd><kwd>recombinant tissue plasminogen activator</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>окклюзия вен сетчатки</kwd><kwd>тромбоз вен сетчатки</kwd><kwd>витреолизис</kwd><kwd>витреоретинальный тракционный синдром</kwd><kwd>рекомбинантный тканевой активатор плазминогена</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Akiba J., Quiroz M. A., Trempe C. L. 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