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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Ophthalmology Reports</journal-id><journal-title-group><journal-title xml:lang="en">Ophthalmology Reports</journal-title><trans-title-group xml:lang="ru"><trans-title>Офтальмологические ведомости</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1998-7102</issn><issn publication-format="electronic">2412-5423</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">7198</article-id><article-id pub-id-type="doi">10.17816/OV10374-84</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">A case of isolated intraocular recurrence of acute lymphoblastic leukemia</article-title><trans-title-group xml:lang="ru"><trans-title>Случай изолированного внутриглазного рецидива острого лимфобластного лейкоза</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Chistyakova</surname><given-names>Natalia V.</given-names></name><name xml:lang="ru"><surname>Чистякова</surname><given-names>Наталья Викторовна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, candidate of medical sciences, ophthalmologist</p></bio><bio xml:lang="ru"><p>канд. мед. наук, врач-офтальмолог</p></bio><email>shadrichev_dr@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Shadrichev</surname><given-names>Fedor E.</given-names></name><name xml:lang="ru"><surname>Шадричев</surname><given-names>Федор Евгеньевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, candidate of medical sciences, head of the ophthalmology department</p></bio><bio xml:lang="ru"><p>канд. мед. наук, заведующий. Офтальмологическое отделение</p></bio><email>shadrichev_dr@mail.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kuznetsova</surname><given-names>Tatiana I.</given-names></name><name xml:lang="ru"><surname>Кузнецова</surname><given-names>Татьяна Игоревна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, ophthalmologist</p></bio><bio xml:lang="ru"><p>врач-офтальмолог</p></bio><email>brionika@gmail.com</email><xref ref-type="aff" rid="aff3"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Scientific Research Institution of Pediatric Oncology, Hematology and Trasplantology n.a. R.M. Gorbacheva clinic</institution></aff><aff><institution xml:lang="ru">НИИ детской онкологии, гематологии и трансплантологии им. Р.М. Горбачевой при ПСПбГМУ им. академика И.П. Павлова</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">St. Peterburg territorial diabetology center</institution></aff><aff><institution xml:lang="ru">Санкт-Петербургский территориальный диабетологический центр</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">Academician I.P. Pavlov First St. Petersburg State Medical University</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО «ПСПбГМУ им. И.П. Павлова» МЗ РФ</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2017-09-15" publication-format="electronic"><day>15</day><month>09</month><year>2017</year></pub-date><volume>10</volume><issue>3</issue><issue-title xml:lang="en">VOL 10, NO3 (2017)</issue-title><issue-title xml:lang="ru">ТОМ 10, №3 (2017)</issue-title><fpage>74</fpage><lpage>84</lpage><history><date date-type="received" iso-8601-date="2017-11-15"><day>15</day><month>11</month><year>2017</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2017, Chistyakova N.V., Shadrichev F.E., Kuznetsova T.I.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2017, Чистякова Н.В., Шадричев Ф.Е., Кузнецова Т.И.</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="en">Chistyakova N.V., Shadrichev F.E., Kuznetsova T.I.</copyright-holder><copyright-holder xml:lang="ru">Чистякова Н.В., Шадричев Ф.Е., Кузнецова Т.И.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">http://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://journals.eco-vector.com/ov/article/view/7198">https://journals.eco-vector.com/ov/article/view/7198</self-uri><abstract xml:lang="en"><p>The development of diagnostic and therapeutic capabilities in hematology contributed to a growth in survival rate in patients with acute leukemia and to the increase in number of different ocular conditions as rare signs of hemoblastosis recurrence and treatment’s side effects. We observed a female patient with extramedullar leukemic ocular damage in acute lymphoblastic leukemia. It is noteworthy that the process of ocular involvement into the underlying disease occurred on the background of complete confirmed hematologic remission.</p></abstract><trans-abstract xml:lang="ru"><p>Развитие диагностических и терапевтических возможностей в гематологии способствовало росту выживаемости пациентов с острым лейкозом и увеличению количества различных глазных проявлений в виде редких признаков рецидивирования гемобластоза и побочных эффектов от лечения. Под наблюдением находилась пациентка с явлениями экстрамедуллярного лейкемического поражения глаза при остром лимфобластном лейкозе. Примечательно, что процесс вовлечения глаза в основное заболевание проходил на фоне полной подтверждённой гематологической ремиссии.</p></trans-abstract><kwd-group xml:lang="en"><kwd>acute lymphoblastic leukemia</kwd><kwd>intraocular extramedullar leukemia recurrence</kwd><kwd>hypopyon-uveitis</kwd><kwd>pseudohypopyon</kwd><kwd>leukemic infiltration</kwd><kwd>intrathecal administration</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>острый лимфобластный лейкоз</kwd><kwd>внутриглазной экстрамедуллярный рецидив лейкоза</kwd><kwd>гипопион-увеит</kwd><kwd>псевдогипопион</kwd><kwd>лейкемическая инфильтрация</kwd><kwd>интратекальные введения</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>1.	Alemayehu W, Shamebo M, Bedri A, Mengistu Z. Ocular manifestations of leukaemia in Ethiopians. Ethiop Med J. 1996;34:217-224.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>2.	Allan R.A, Straatsma BR. 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