I.P. Pavlov Russian Medical Biological HeraldI.P. Pavlov Russian Medical Biological HeraldРоссийский медико-биологический вестник имени академика И.П. Павлова0204-34752500-2546Eco-Vector5270010.23888/PAVLOVJ2020284605-612ReviewНаучные обзорыReview ArticleReticulocyte haemoglobin content: 2020 updateСодержание гемоглобина в ретикулоцитах: новости 2020网织红细胞血红蛋白含量：2020年更新https://orcid.org/0000-0002-3656-7266ABD-8614-2020EreminaYuliana O.ЕрёминаЮлиана Олеговна
Portugal

MD, PhD, Specialist in Clinical Pathology, Assistant of the Department of Clinical Pathology, Hospital Pedro Hispano, Collaborator of Environmental and Laboratorial Epidemiology Research Group (EPIUnit), Environmental Health Department

к.м.н., специалист в области клинической патологии, ассистент отделения клинической патологии; сотрудник исследовательской группы по экологической и лабораторной эпидемиологии, Департамент охраны окружающей среды

yuliana.eremina@ulsm.min-saude.pthttps://orcid.org/0000-0001-7407-4908MagalhãesCacildaМагаляешК.
Portugal

MD, Consultant in Clinical Pathology, Director of the Department of Clinical Pathology

д.м.н., консультант по клинической патологии, директор отделения клинической патологии

Cacilda.Magalhaes@ulsm.min-saude.ptHospital Pedro Hispano, Local Health Unit of MatosinhosБольница Педро Ишпану, Местное отделение здравоохранения МатозиньюшаInstitute of Public Health of the University of PortoИнститут общественного здравоохранения Университета ПортуHospital Pedro Hispano, Local Health Unit of MatosinhosБольница Педро Ишпану, Местное отделение здравоохранения Матозиньюша151220202846056123011202016122020Copyright ©; 2021, OOO "Эко-Вектор"Copyright ©; 2021, Eco-VectorCopyright ©; 2021, Eco-Vector2021OOO "Эко-Вектор"Eco-VectorEco-Vectorhttps://journals.eco-vector.com/pavlovj/article/view/52700

The hemoglobin content of reticulocytes (Hb-ret) is an effective real-time hemoglobin synthesis status indicator that permits diagnosis and monitoring of iron deficiency and iron deficiency anemia in all age groups with or without underlying diseases, including beta thalassemia. Hb-ret is less invasive than bone iron examination, less expensive than iron biochemical tests and might be available even in local laboratories. This review covers reports published mainly in 2020 and some other studies dedicated to clinical application of Hb-ret measured by Sysmex hematology analyzers.

Содержание гемоглобина в ретикулоцитах (Hb-ret) является эффективным индикатором состояния синтеза гемоглобина в реальном времени, который позволяет диагностировать и контролировать дефицит железа и железодефицитную анемию во всех возрастных группах с сопутствующими заболеваниями или без них, включая бета-талассемию. Анализ Hb-ret – менее инвазивный метод, чем исследование железа костного мозга, менее дорогой, чем биохимический анализ показателей обмена железа, и может быть доступен даже в местных лабораториях. Этот обзор посвящен материалам, опубликованным, в основном в 2020 г., и некоторым исследованиям клинического применения Hb-ret измеренного на гематологических анализаторах Sysmex.

网织红细胞血红蛋白含量（Hb-ret）是一种实时血红蛋白合成状态有效指标，可用于所有年龄组缺铁和缺铁性贫血的诊断并监测，不论是否存在基础病（包括β-地中海贫血）。Hb-ret检测比骨铁检查侵入性更小，比铁生化检查更便宜，甚至在本地实验室即可实现。本综述主要涵盖了发表于2020年的报告和其他关注使用Sysmex血液分析仪测量Hb-ret的临床应用研究。

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