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Vol 25, No 4 (2017) Study of fabomotizole belonging to p-glycoprotein substrates
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Chernykh I.V., Shchulkin A.V., Yakusheva E.N., Gatsanoga M.V., Popova N.v.
"... of fabomotizole to Pgp substrates was evaluated by comparing pharmacokinetic parameters of the test-substance ..."
Vol 23, No 3 (2015) METHODS OF IDENTIFICATION OF DRUGS AS P-GLYCOPROTEIN SUBSTRATES
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Yakusheva E.N., Chernykh I.V., Shulkin A.V., Gatsanoga M.V.
"... the pharmacokinetics of fexofenadine - known Pgp substrate at a dose of 67,5 mg/kg, before and after the 14-days ..."
Vol 25, No 1 (2017) ANALYSIS OF ATTRIBUTION OF NOOPEPT TO SUBSTRATES AND MODULATORS OF FUNCTIONAL ACTIVITY OF ABCB1-PROTEIN IN IN VIVO EXPERIMENT
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Chernykh I.V., Shchulkin A.V., Yakusheva E.N., Gatsanoga M.V., Popova N.M.
"... was estimated by the pharmacokinetics of its marker substrate - fexofenadine. Fexofenadine was introduced ..."
Vol 21, No 1 (2013) THE INFLUENCE OF EXPERIMENTAL SUBACUTE HYPOBARIC HYPOXIA ON P-GLYCOPROTEIN FUNCTIONAL ACTIVITY
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Yakusheva E.N., Chernykh I.V.
"... was assessed by pharmacokinetic of it’s marker substrate fexofenadine. It was found that 4-hour hypoxic action ..."
Vol 21, No 4 (2013) Oral hormonal contraceptive "janine" influence on P-glycoprotein functional activity
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Yakusheva E.N., Kotlyarova A.A., Nikiforov A.A.
"... by pharmacokinetic analysis of marker substrate fexofenadine. It was found that administration of the drug "Janine ..."
Vol 20, No 4 (2012) FINASTERIDE INFLUENCE ON P-GLYCOPROTEIN FUNCTIONAL ACTIVITY
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Yakusheva E.N., Chernykh I.V.
"... efflux transporter P-glycoprotein (Pgp) was studied. Pgp activity was assessed by pharmacokinetic ..."
Vol 22, No 2 (2014) ORAL HORMONAL CONTRACEPTIVE "YARINA" INFLUENCE ON P-GLYCOPROTEIN FUNCTIONAL ACTIVITY
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Kotljarova A.A., Yakusheva E.N.
"... by pharmacokinetic analysis of marker substrate fexofenadine. It was found that administration of the drug "Yarina ..."
Vol 19, No 4 (2011) Influence of the thyroxine on the functional activity of the р-glycoprotein in the experiment
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Yakusheva E.N., Byryukova A.S., Shchulkin A.V., Nikiforova L.V.
"... - transporter Р-glycoprotein (Pgp) was studied. Activity of the Pgp was investigated on the pharmacokinetics ..."
Vol 19, No 3 (2011) Characteristic of p-glycoprotein as a drug peptide transporter
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Yakusheva E.N., Chernykh I.V., Biruicova A.S.
"... Review characterizes the urgency of problem, chemical properties of P-glycoprotein substrates ..."
Vol 22, No 2 (2014) FUNCTIONAL ACTIVITY OF P-GLYCOPROTEIN DURING EXPERIMENTAL MANIPULATIONS
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Yakusheva E.N., Shulkin A.V., Chernykh I.V., Titov D.S.
"... by pharmacokinetic analysis of its marker substrate - fexofenadine. Found that manipulations applied do not lead ..."
Vol 26, No 2 (2018) Possibilities of use of plant derived nonstarch polysaccharides in clinical practice
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Chernykh I.V., Kirichenko E.E., Shchulkin A.V., Popova N.M., Kotlyarova A.A.
"... Inhibition of Pglycoprotein transporter protein (ABCB1protein, Pgp) is a promising method ..."
Vol 23, No 3 (2015) EFFECT OF AN INHIBITOR OF DPP-4-VTLDAGLIPTIN FOR THE FUNCTIONAL ACTIVITY OF P-GLYCOPROTEIN IN VIVO
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Titov D.S., Nikiforova L.V.
"... activity was evaluated by its pharmacokinetics marker substrate - fexofenadine after a single intragastric ..."
Vol 23, No 4 (2015) Effect of gliquidone on the ABCB1 protein functional activity in vivo
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Titov D.S., Nikiforov A.A., Pravkin S.K.
"... activity was evaluated by pharmacokinetics of its marker substrate - fexofenadine after a single ..."
Vol 19, No 4 (2011) Pharmacokinetic of simvastatin at experimental hypothyreosis
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Yakusheva E.N., Popova N.M.
"... In article data of the research devoted to studying of pharmacokinetic of simvastatin ..."
Vol 23, No 4 (2015) P-glycoprotein expression in brain during ischemia-reperfusion
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Yakusheva E.N., Chernykh I.V., Shchulkin A.V., Vinogradov I.Y.
"... -транспортера гликопротеина-Р в головном мозге и оценена ее взаимосвязь с уровнем окислительного стресса ткани ..."
Vol 20, No 3 (2012) DEVELOPMENT AND PHARMACOKINETIC STUDIES CHILD DRUG FORM -SUPPOSITORIES WITH ARBIDOL
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Vorobyov A.N., Ovcharov M.V., Potanina O.G., Abramovich R.A.
"... of the antiviral drug for children based on the domestic substances. Carried out of pharmacokinetic studies ..."
Vol 25, No 2 (2017) EXPERIMENTAL PHARMACOKINETIC STUDY OF ZINC WHEN ZINC HYDROXIDE NANOFORM IS ADMINISTERED ENTERALY AND INTRAVASCULARY
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Larin S.L., Zvyagintseva A.R., Khabarov A.A., Budko E.V., Artushkova E.B.
"... In vivo experiments on rabbits studied pharmacokinetic properties of Zn2+ under administration ..."
Vol 25, No 2 (2017) Experimental pharmacokinetic study of the zinc when zinc hydroxide nanoform administrated enteral and intravascular
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Larin S.L., Zvyagintseva A.R., Khabarov A.A., Budko E.V.
"... In the experiments in vivo on rabbits studied pharmacokinetic properties of Zn2+ under ..."
Vol 20, No 2 (2012) Expression of GABA transporter (GAT-1) and GLIAL FIDRILLAR ACIDIC PROTEIN (GFAP) in maturated human neocortex
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Godovalova O.S., Savel’ev S.V.
"... Изучено распределение ГАМК транспортера (GAT-1) в бороздах неокортекса человека с 14 недель ..."
Vol 23, No 4 (2015) Association between the activity of enzyme CYP3A4 and profile of efficacy and safety of haloperidol in patiens with alcohol addiction
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Zastrozhin M.S., Smirnov V.V., Sychev D.A., Savchenko L.M., Bryun E.A., Guschina Y.S., Esakova A.P., Galaktionova T.E.
"... endogenous substrate of this isoenzyme and its metabolite in urine - (the ratio of 6-beta-hydrocortizol ..."
Vol 23, No 2 (2015) DISTRIBUTION AND DYNAMICS OF CHEMICAL ELEMENTS IN PINE ECOSYSTEMS MESHCHERSKY WOODLAND
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Podol S.R., Popova Z.I.
"... biogeocenoses formed on mineralogiccally a poor substrate, under conditions of pronounced deficit of nutrients ..."
Vol 24, No 3 (2016) INFLUENCE OF VILDAGLIPTIN AND GLIQUIDONE COMBINATION ON P-GLYCOPROTEIN FUNCTIONAL ACTIVITY AND EXPRESSION ON THE BACKGROUND OF NORM AND IN EXPERIMENTAL ALLOXAN-INDUCED DIABETES MELLITUS TYPE 2
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Yakusheva E.N., Titov D.S., Nikiforov A.A.
"... отмены указанной комбинации наблюдалось ингибирование функциональной активности белка-транспортера, без ..."
Vol 20, No 2 (2012) COMPLEX ASSESSMENT OF CHRONIC TOXICITY OF THE PREPARATIONS FROM THE BIOMASS OF THE POLISCIAS FICIFOLIA BAILEY CELLULAR CULTURE AS PART OF ITS PRECLINICAL STUDY
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Ryabkov A.N.
"... . Это подтверждает его значимость как перспективного субстрата для получения лекарственных средств ..."
Vol 25, No 4 (2017) The use of plasmapheresis and intravenous laser blood irradiation in treatment of patients with newly diagnosed tuberculosis at the late stages of hiv infection (references review)
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Polyakov A.A., Kornilova Z.H., Demikhova O.V.
"... ) is the most effective generic method of detoxification of the body that removes various substrates present ..."
Vol 25, No 2 (2017) SPECTROPHOTOMETRIC DETERMINATION OF IZONIAZID AND ITS DERIVATIVES BY REACTION OF FORMATION THE POLYMETHINE DYE WITH 4-OXOURACIL
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Gromova Z.F., Chekulaeva G.Y.
"... it possible to evaluate the activity of N-acetyltransferase during pharmacokinetic studies. ..."
Vol 23, No 1 (2015) Development of HPLC method of ethyl-methylhydroxypyridine succinate quantification in rat and rabbit plasma
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Chernykh I.V., Shchulkin A.V., Gatsanoga M.V., Mylnikov P.Y.
"... субстратам, индукторам, ингибиторам семейства цитохромов P450 и белков-транспортеров [7, 9]. В связи с ..."
Vol 26, No 2 (2018) The effect of arginine on the activity and compartmentalization of lysosomal cysteine proteinases of parenchymatous organs in oxidative stress on the background of experimental hyperhomocysteinemia
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Fomina M.A., Terent'ev A.A.
"... ] was modeled by intragastric introduction of methionine as a substrate for synthesis of homocysteine ..."
Vol 26, No 1 (2018) Acromegaly and comorbid conditions. New possibilities of diagnosis and treatment (literature review)
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Zhulidova A.U., Dubinina I.I.
"... pharmacokinetic effect without any initial spikes of increased concentrations, ready for use pharmaceutical form ..."
Vol 19, No 3 (2011) The study of anthihypoxic and antiischemic activity of phytoecdysterone
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Shchulkin A.V., Davydov V.V., Yakusheva E.N., Krasnolobov A.G.
"... методика Г. Селье (1958), основанная на выявлении фуксинофильного субстрата. Принято считать, что его ..."
Vol 23, No 2 (2015) CHANGES IN THE CONTRACTILE CARDIOMYOCYTES AND HEMOMICROCIRCULATORY BED IN PREGNANT RATS AND THEIR PUPS EXPOSED TO HEMIC HYPOXIA
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Zadnipryany I.V., Tret'yakova O.S., Sataieva T.P.
"... диффузное накопление фуксинофильного субстрата что подтверждалось данными ГОФП-окрашивания. Данные изменения ..."
Vol 22, No 2 (2014) SPECIFICS OF POLYMORPHISMS OF GENES OF AGO1, DGCR8, GEMIN4, DROSHA IN PATIENTS WITH HYPERTENSION AND POST-INFARCTION CARDIOSCLEROSIS
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Shcheglova N.E., Kalinkin M.N.
"... . – № 4(96). 2. Полиморфизм гена транспортера до- фамина DAT1 и индивидуальная ва- риабельность ..."
Vol 18, No 3 (2010) Unrevealed In clinical practice, acute form of ischemic heart disease: frequency, Laws, impact on Epidemiology
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Nikulina N.N., Yakushin S.S., Nikulina N.N., Yakushin S.S.
"... . Priori S. Concealed arrhythmogenic syndromes: the hidden substrate of idiopathic ventricular ..."
Vol 23, No 3 (2015) AN ANALYSIS OF PROBABLE MECHANISMS OF ANTIDEPRESSANT ACTIVITY OF NEURONAL N-METHYL-D-ASPARTATE RECEPTOR BLOCKERS
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Abramets I.I., Evdokimov D.V.
"... (nNOS). Кроме того, отмечено угнетение экспрессии глиальных транспортеров глутамата, которое приводит к ..."
Vol 21, No 3 (2013) DRUG-DRUG INTERACTIONS IIKE A REASON OF ADVERSE DRUG REACTIONS
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Kazakov A.S., Lepakhin V.K., Astakhova A.V.
"... -транспортеров взаимодействующих ЛС. Так, в 1978 году, была опубликована информация о наблюдении того, что ..."
Vol 24, No 3 (2016) SYSTEMIC AL-AMYLOIDOSIS: PROBLEMS OF DIAGNOSIS (LITERATURE REWIEW AND CLINICAL CASE
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Smirnova E.A., Abdurakhmanova E.K., Filonenko S.P.
"... - dial substrate of cardiac amyloidosis by gadolinium cardiac magnetic resonance // Heart. 2006. Vol ..."
Vol 14, No 2 (2006) The choice of of efficient antioxidant dose of ionol for the tissue of lens in local instillation introduction of its oil solution
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Kolesnikov A.V.
"... . Один из изоферментов GSH-tr, субстратом которого являются органические ГП, способен восстанавливать за ..."
Vol 19, No 1 (2011) DEFINITION ADHESIVE OF PROPERTIES TRANSDERMAL OF THE PLASTER WITH MEXIDOL
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Losenkova S.O., Kirillov S.K., Stepanova E.F., Novikov V.E., Losenkova S.O., Kirillov S.K., Stepanova E.F., Novikov V.E.
"... субстратом вследствие шероховатости поверхностей. Материалы и методы В состав сконструированного нами ..."
Vol 17, No 2 (2009) THE CELLULAR STRUCTURE CHARACTERISTIC OF MEDIAL NUCLEUSES IN MAMILLAR BODIES OF THEINTERMEDIATE BRAIN AT MEN AND WOMEN IN AGE OF 50-60 YEARS
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Pavlov A.V.
"... . Цитоплазма этих клеток замещена белковым слабобазофильным субстратом, ядерных фрагментов не определяется ..."
Vol 18, No 3 (2010) Markers of metabolic syndrome in women in the remote period after surgical correction of gastrointestinal diseases
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Ivanov V.V., Puchkov K.V., Ivanov V.V., Puchkov K.V.
"... артериальной, венозной системе и др.), ликвидация первичного гормонозависимого субстрата (миомэктомия, аблация ..."
Vol 19, No 4 (2011) Comparative histochemical characteristic of different parts of cerebral cortex in rats after irradiation
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Ilicheva V.N.
"... тетразолийредуктазными методиками с использованием соответствующего субстрата и соли “нитро-СТ” в модификации Нахаласа [8 ..."
Vol 22, No 2 (2014) INDUCERS OF THE REGULATORY FACTOR TO HYPOXIA ADAPTATION
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Levchenkova O.S., Novikov V.E.
"... транспортера гли-копротеина-Р и др. [13, 20, 38]. Синтез HIF-1a может реализовываться через кислород ..."
Vol 19, No 2 (2011) MORPHOLOGICAL CHARACTERISTICS OF IN THE MEDIAL NUCLEI IN MAMMILLARY BODIES OF BRAIN OF MEN WITH CHRONIC ALCOHOL INTOXICATION
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Pavlov A.V., Pavlov A.V.
"... субстратом, ядерных фрагментов не определяется. В препаратах лиц с алкогольной интоксикацией также ..."
Vol 21, No 4 (2013) Phenotypic markers of connective tissue dysplasia in primary spontaneous pneumothorax
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Miheev A.V., Trushin S.N., Baskevich M.A.
"... -антипротеазная теория в полной мере не может описать генез развития буллезной эмфиземы легких как субстрата для ..."
Vol 22, No 4 (2014) Histological interpretation severity of dysplasia of connective tissue in clinical practice
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Uhov U.I., Sobennikov I.S., Kotans S.Y., Cherenkov A.A.
"... заболеваний [2, 6, 10]. Одним из широко обсуждаемых патогенетических субстратов генеза множества клинических ..."
Vol 20, No 1 (2012) The effect of small doses of ionizing irradiation on histochemical characteristics of rats brain cortex
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Ilicheva V.N., Ushakov B.N.
"... методиками с использованием со- ответствующего субстрата и соли «нитро- СТ» в модификации Нахаласа [6]. Актив ..."
Vol 21, No 2 (2013) PECULIARITIES OF TREATMENT AND PROPHYLAXIS OF INITIAL CARIES AND CHRONIC CATARRHAL GINGIVITIS
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Galizina O.A.
"... , ферментирующими углеводы [19]. Поступление субстрата в зубной налет осуществляется путем сложных биохимических ..."
Vol 20, No 1 (2012) RESEARCH OF THE INDICATORS OF THE OXIDATIVE STRESS IN THE OSTEOARTHROSIS OF THE BLOOD
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Trilis Y.G., Mescheryakova M.G., Kirillova N.V., Alpatova T.F., Muhin I.A., Kozhevin A.A.
"... миелопероксидазы с использованием наборов ЗАО «Алкор Био» в качестве субстрата-восстановителя выступал ..."
Vol 20, No 2 (2012) Ultrasound duplex scanning in evaluation of long-term results of reconstructive surgery in patients with peripheral occlusive arterial disease
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Kalinin R.E., Suchkov I.A., Puchkova G.A.
"... - цией субстрата по-прежнему явился пе- риферический анастомоз. Через 6 месяцев тромбоз шунта раз ..."
Vol 24, No 1 (2016) The urgency of the problem of adhesions in the pelvis, its consequences and the role of undifferentiated connective tissue dysplasia in its development
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Repina N.B., Ben Salha M.
"... других исследований высказан ряд гипотез об участии сосудистых реакций, различных белковых субстратов и ..."
Vol 21, No 1 (2013) ARSENAL OF MODERN MEDICAL LINERS USED IN DENTISTRY (REVIEW OF LITERATURE DATA)
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Chen W., Elouazzani M., Kazanceva G.P.
"... - рилизованная костная мука представляет собой депо органических и неорганиче- ских субстратов и успешно ..."
Vol 19, No 2 (2011) POSSIBLE WAYS OF STIMULATION OF NITRIC OXIDE PRODUCTION AS THE MAIN INDUCTOR OF ENDOTHELIAL DYSFUNCTION USING CARDIOTROPIC DRUGS IN PATIENTS WITH PERIPHERAL OCCLUSIVE ARTERIAL DISEASE
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Shval'b P.G., Kalinin R.E., Pshennikov A.S., Shvalb P.G., Kalinin R.E., Pshennikov A.S.
"... возможно приемом L-аргинина, условно-незаменимой аминокислоты. Аргинин является субстратом NO-синтаз в ..."
Vol 18, No 1 (2010) Oxidizing modificationof albumens in plasmaof blood of patients bydiabetes mellitus oftype 2 iin dependence ondegree ofindemnification ofcarbohydrateexchange and durationof diabetes mellitus oftype 2
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Zanozina O.V., Shcherbatyuk T.G., Borovkov N.N., Zanozina O.V., Scherbatuc T.G., Borovkov N.N.
"... увеличивается количество субстрата для перекисного окисления липидов (p=0,012) и генерации свободных ..."
Vol 18, No 1 (2010) Complex treatment of venoustrophic ulcers and the new conceptof pathogenesis
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Shval'b P.G., Shval'b A.P., Gryaznov S.V., Shvalb P.G., Shvalb A.P., Griaznov S.V.
"... . Следовательно, в первом варианте излечение возможно при ликвидации субстрата болезни, а во втором – при ..."
Vol 23, No 3 (2015) EPITHELIAL AND STROMAL COMPONENTS IN DUCTAL BREAST CANCER
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Mnikhovich M.V.
"... реорганизация комплексов, обеспечивающих прикрепление клетки к субстрату. Однако частично сохраненная экспрессия ..."
Vol 20, No 4 (2012) STUDY OF SYSTEMIC INFLAMMATION IN PATIENTS BRONCHIAL ASTHMA IN COMBINATION WITH METABOLIC SYNDROME
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Sysoeva M.S., Solovieva A.V., Nikiforova L.V., Rakita D.R.
"... субстратов в слизистых бронхов и эндотелии сосудов 1, 7]. В последнее время получено много данных о том, что ..."
Vol 17, No 4 (2009) SURGICAL TREATMENT OF WELL DIFFERENTIATED THYROID CANCER T1 - T2
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Polyakov V.G., Aristarkhov V.G., Shilovа M.I.
"... , поскольку в этом случае не остается субстрата для развития очагов РЩЖ. По нашим данным у 8 пациентов после ..."
Vol 17, No 4 (2009) The influence of some environmental factors on an accumulation of biologically active substances in the Amelanchier vulgaris
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Laksaeva E.A., Sytchev I.A.
"... субстрата окисления и источника кислорода, в результате чего увеличивается количество сахаров, продуктом ..."
Vol 18, No 3 (2010) Pathogenesis of trophic venous ulcers the choice of methods therapeutic
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Shval'b P.G., Shval'b A.P., Gryaznov S.V., Shvalb P.G., Shvalb A.P., Griaznov S.V.
"... излечение возможно при ликвидации субстрата болезни, а во втором – при разрыве патогенетической связи ..."
Vol 14, No 2 (2006) Hodzkina Lymphoma in children: Its frequency during 1996 - 2006 in Ryazan region, Questions of complex cytology and histology diagnotics
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Pankratova E.S., Mnikhovich M.V.
"... . Субстратом лимфогранулематоза считается полиморфноклеточная гранулема, образованная лимфоцитами ..."
Vol 24, No 2 (2016) Study of L-carnitine effect on the activity of cathepsins B, L, H, and oxidative modification of proteins in muscle organs of rats
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Arapova A.І., Fomina M.A.
"... введением карни-тина, является, вероятно, истощение субстрата у группы с применением изолированного ..."
Vol 24, No 2 (2016) The alterations of neurophysiological parameters of the anterior cingulate cortex in the experimental depressive syndrome of different genesis
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Abramets I.I., Evdokimov D.V., Zayka T.O.
"... субстратов. Не исключено, что выявленные нами изменения синаптической передачи развиваются по такому же ..."
Vol 21, No 2 (2013) HYGIENIC AND EPIDEMIOLOGICAL ASPECTS OF THE WORK OF MODERN OBSTETRIC FACILITIES
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Kiriushin V.A., Kotelevets E.P.
"... связано с тем, что пыль на поверхности воздуховодов в присутствии конденсата является хорошим субстратом ..."
Vol 20, No 4 (2012) NEW CONCEPTS OF PHARMACODYNAMICS OF ECDYSTEROIDS
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Shchulkin A.V., Yakusheva E.N., Davydov V.V., Darmograi V.N.
"... . Активированная киназа Akt далее регулирует через фосфорилирова-ние активность многих субстратов 23]. Было ..."
Vol 21, No 3 (2013) THE SYSTEM ORGANISATION OF SUBJECTIVE PROCESSES IN A BRAIN
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Yumatov E.A.
"... вопросы о происхождении психогенного поля, с каким мозговым субстратом связано его существование, и на ..."
Vol 22, No 2 (2014) The peculiarities of intermitochondrial contacts during ontogenetic formation of mitochondria network in normal and under hypoxic damage of cardiogenesis
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Ivanchenko M.V., Tverdokhleb I.V.
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