Pediatrician (St. Petersburg)Pediatrician (St. Petersburg)2079-78502587-6252Eco-Vector1352410.17816/PED102129-135Research ArticleAlgorithm of hearing monitoring of children with congenital heart diseaseGarbarukEkaterina S.<p>PhD, Senior Researcher, Research Center</p>kgarbaruk@mail.ruNnomzooAlice A.<p>Postgraduate Student, Department of Otorhinolaryngology</p>nnomzoalice@gmail.comPavlovPavel V.<p>MD, PhD, Dr Med Sci, Professor, Head, Department of Otorhinolaryngology</p>pvpavlov@mail.ruGorkinaOksana C.<p>Assistant Professor, Department of Otorhinolaryngology</p>gorkina-ok@yandex.ruSt. Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation190620191021291351806201918062019Copyright © 2019, Garbaruk E.S., Nnomzoo A.A., Pavlov P.V., Gorkina O.C.2019<p>Congenital heart disease (CHD) is one of the most common types of birth defect. Often newborn hearing screening is not performed for infants with congenital heart disease because of serious health problems at birth. Hearing loss in children with CHD may have late onset due to different stages of CHD treatment. The monitoring of the auditory function is required for early identification of hearing loss in children with CHD, however algorithm of follow-up assessment is not currently defined.</p>
<p><strong>Objective </strong> estimation of prevalence, types and time of hearing loss onset in children with congenital heart disease and development a follow-up assessment for CHD children.</p>
<p><strong>Results.</strong> 148 children with congenital heart disease have been evaluated with auditory brainstem response testing, otoacoustic emissions, impedancemetry, behavioral hearing tests. The patients ranged in age from 7 days to 6 years. 55 children had hearing loss: 28 children with conductive hearing loss and 27 children with sensorineural hearing loss, 2 of them with auditory neuropathy. 6 children had late onset sensorineural hearing loss. The age of delayed hearing loss identification ranged from 4 months to 5 years.</p>
<p><strong>Conclusion.</strong> Children with CHD require long-term monitoring of the auditory function; an algorithm of follow-up assessment for children with congenital heart disease is proposed. Audiological assessment in children with CHD should include auditory brainstem response registration for auditory neuropathy identification.</p>sensorineural hearing lossauditory neuropathycongenital heart diseasefollow-up assessmentchildrenсенсоневральная тугоухостьслуховая нейропатияврожденный порок сердцадинамическое наблюдениедети[Журавский С.Г., Томсон В.В., Цвылева И.Д., и др. Патоморфологические аспекты действия аминогликозидных антибиотиков на слуховой анализатор // Вестник оториноларингологии. – 2003. – № 2. – С. 55–60. [Zhuravskiy SG, Tomson VV, Tsvyleva ID, et al. Patomorfologicheskie aspekty deystviya aminoglikozidnykh antibiotikov na slukhovoy analizator. Vestn Otorinolaringol. 2003;(2):55-60. (In Russ.)]][Нномзоо А., Павлов П.В., Гарбарук Е.С., и др. Состояние слухового анализатора у младенцев с врожденными пороками сердца // Педиатр. – 2017. – Т. 8. – № 3. – С. 81–87. [Nnomzo’o A, Pavlov PV, Garbaruk ES, et al. The auditory function of infants with congenital heart diseases. Pediatrician (St. Petersburg). 2017;8(3):81-87. (In Russ.)]. https://doi.org/10.17816/PED 8381-87.][Савенко И.В., Бобошко М.Ю., Гарбарук Е.С. Экссудативный средний отит у детей, родившихся недоношенными: этиопатогенез, характер течения и исходы // Folia Otorhinolaryngologiae et Pathologiae Respiratoriae. – 2018. – Т. 24. – № 4. – С. 27–37. [Savenko IV, Boboshko MY, Garbaruk ES. Otitis media with effusion in children born prematurely: etiopathogenesis, course and outcomes. Folia Otorhinolaryngologiae et Pathologiae Respiratoriae. 2018;24(4):27-37. (In Russ.)]][Таварткиладзе Г.А. Руководство по клинической аудиологии. – М.: Медицина, 2013. [Tavartkiladze GA. Rukovodstvo po klinicheskoy audiologii. Moscow: Meditsina; 2013. (In Russ.)]][Шабалов Н.П. Детские болезни. Т. 2: учебник. 8 изд. – СПб: Питер, 2017. [Shabalov NP. Detskie bolezni. Vol. 2: textbook. 8th ed. Saint Peterburg: Piter; 2017. (In Russ.)]][Школьникова М.А., Абдулатипова И.В., Осокина Г.Г. Основные тенденции заболеваемости и смертности от сердечно-сосудистых заболеваний детей и подростков в Российской Федерации // Российский вестник перинатологии и педиатрии. – 2008. – Т. 53. – № 4. – С. 4–14. [Shkolnikova MA, Abdulatipova IV, Nikitina SY, Osokina GG. Basic trends in cardiovascular morbidity and mortality in children and adolescents in the Russian Federation. Rossiiskii vestnik perinatologii i pediatrii. 2008;53(4):4-14. (In Russ.)]][Abrashkin KA, Izumikawa M, Miyazawa T, et al. The fate of outer hair cells after acoustic or ototoxic insults. Hear Res. 2006;218(1-2):20-29. https://doi.org/10.1016/j.heares.2006.04.001.][Arndt S, Laszig R, Beck R, et al. Spectrum of Hearing Disorders and Their Management in Children With CHARGE Syndrome. Otol Neurotol. 2010;31(1):67-73. https://doi.org/10.1097/MAO.0b013e3181c0e972.][Arnold SA, Brown OE, Finitzo T. Hearing loss in children with congenital heart disease: a preliminary report. Int J Pediatr Otorhinolaryngol. 1986;11(3):287-293. https://doi.org/10.1016/s0165-5876(86)80041-6.][Fligor BJ, Neault MW, Mullen CH, et al. Factors associated with sensorineural hearing loss among survivors of extracorporeal membrane oxygenation therapy. Pediatrics. 2005;115(6):1519-1528. https://doi.org/10.1542/peds.2004-0247.][Huth ME, Ricci AJ, Cheng AG. Mechanisms of aminoglycoside ototoxicity and targets of hair cell protection. Int J Otolaryngol. 2011;2011:937861. https://doi.org/10.1155/2011/937861.][Joint Committee on Infant Hearing. Year 2007 position statement: Principles and guidelines for early hearing detection and intervention programs. Pediatrics. 2007;120(4):898-921. https://doi.org/10.1542/peds.2007-2333.][Marino BS, Lipkin PH, Newburger JW, et al. Neurodevelopmental outcomes in children with congenital heart disease: evaluation and management: a scientific statement from the American Heart Association. Circulation. 2012;126(9):1143-1172. https://doi.org/10.1161/CIR.0b013e318265ee8a.][Rastogi S, Mikhael M, Filipov P, Rastogi D. Effects of ventilation on hearing loss in preterm neonates: Nasal continuous positive pressure does not increase the risk of hearing loss in ventilated neonates. Int J Pediatr Otorhinolaryngol. 2013;77(3):402-406. https://doi.org/10.1016/j.ijporl.2012.11.040.][Sopontammarak S, Khongphatthanayothin A, Sa-Nguanchua P. Prevalence of idiopathic long QT syndrome in congenital sensori-neural hearing loss students of Songkhla School for the Deaf. J Med Assoc Thai. 2003;86(12):1149-1155.d.][van Trier DC, van Nierop J, Draaisma JM, et al. External ear anomalies and hearing impairment in Noonan Syndrome. Int J Pediatr Otorhinolaryngol. 2015;79(6): 874-878. https://doi.org/10.1016/j.ijporl.2015.03.021.][Yoshinaga-Itano C. Principles and guidelines for early intervention after confirmation that a child is deaf or hard of hearing. J Deaf Stud Deaf Educ. 2014;19(2):143-75. https://doi.org/10.1093/deafed/ent043.]