Pediatrician (St. Petersburg)Pediatrician (St. Petersburg)2079-78502587-6252Eco-Vector788110.17816/PED8686-93Research ArticleMR-patterns of brain’s hypoxic-ischemic lesions in term newbornsMelashenkoTat'yana V.<p>PhD</p>pozdnyakovalex@ya.ruPozdnyakovAleksandr V.<p>MD, PhD, Dr Med Sci, Professor, Head of Department of Radiodiagnosis, Head of the Department of Medical Biophysics</p>pozdnyakovalex@ya.ruLvovViktor S.<p>post-graduate, Department of Medical Biophysics</p>viktorlvov@list.ruIvanovDmitry O.<p>MD, PhD, Dr Med Sci, Professor, Rector</p>doivanov@yandex.ruSt. Petersburg State Pediatric Medical University2812201786869308022018Copyright © 2017, Melashenko T.V., Pozdnyakov A.V., Lvov V.S., Ivanov D.O.2017<p>Perinatal hypoxic-ischemic encephalopathy (HIE) remains a major cause of neonatal mortality and development of severe neurological disorders that determine the quality of life of these children. In developed countries, the frequency of detection of hypoxic-ischemic encephalopathy (HIE) among full-term newborns is 1-6 per 1.000 live births. In our country, hypoxic-ischemic brain damage is observed in 15-30% of full-term newborns. The term HIE is a clinical diagnosis combining neurological disorders and biochemical changes caused by perinatal HI (hypoxiа-ischemia). The pattern of acute brain damage depends on the degree of cerebral maturity, the severity and duration of hypoxiа-ischemia. The most vulnerable regions are the structures of the brain with high level of metabolism. Such structures in term infants include cortical neurons and neurons of basal nuclei, a subcortical white matter. MRI allows to diagnose brain lesions in term infants in the acute period of HIE. Safety, non-invasiveness and large diagnostic capabilities of MRI allow this method to be considered the gold standard of neuroimaging in neonatology. 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