JUVENILE ARTHRITIS: CLINICAL MANIFESTATIONS AND DIFFERENTIAL DIAGNOSIS AND DIFFERENTIAL DIAGNOSIS

Cover Page


Cite item

Full Text

Abstract

The diagnosis and treatment of inflammatory joint diseases is the pressing problem of pediatric rheumatology and orthopedics. Juvenile arthritis is the most frequent chronic inflammatory disease of the musculoskeletal system in children and adolescents. Still juvenile arthritis is often misdiagnosed. The article provides current knowledge on juvenile arthritis, its clinical manifestations, as well as diagnostic and treatment strategies, and differential diagnosis.

About the authors

Aleksei Nikolaevich Kozhevnikov

FSBI “Scientific and Research Institute for Children’s Orthopedics n. a. G. I. Turner” under the Ministry of Health of the Russian Federation

Email: Infant_doc@mail.ru
MD, PhD, pediatric rheumatologist of the department of trauma effects and rheumatoid arthritis

Nina Anatolievna Pozdeeva

FSBI “Scientific and Research Institute for Children’s Orthopedics n. a. G. I. Turner” under the Ministry of Health of the Russian Federation

Email: pozdeeva.nina@gmail.com
MD, PhD, pediatric rheumatologist, deputy chief doctor of medical treatment

Mikhail Aleksandrovich Konev

FSBI “Scientific and Research Institute for Children’s Orthopedics n. a. G. I. Turner” under the Ministry of Health of the Russian Federation

MD, head of the department of trauma effects and rheumatoid arthritis.

Vladimir Vasilievich Selizov

FSBI “Scientific and Research Institute for Children’s Orthopedics n. a. G. I. Turner” under the Ministry of Health of the Russian Federation

MD, pediatric rheumatologist, orthopedic surgeon of the department of trauma effects and rheumatoid arthritis

Evgenii Vladimirovich Prokopovich

FSBI “Scientific and Research Institute for Children’s Orthopedics n. a. G. I. Turner” under the Ministry of Health of the Russian Federation

MD, PhD, orthopedic surgeon of the department of trauma effects and rheumatoid arthritis.

Maksim Sergeevich Nikitin

FSBI “Scientific and Research Institute for Children’s Orthopedics n. a. G. I. Turner” under the Ministry of Health of the Russian Federation

MD, orthopedic surgeon of the department of trauma effects and rheumatoid arthritis

Aleksei Vitalievich Moskalenko

FSBI “Scientific and Research Institute for Children’s Orthopedics n. a. G. I. Turner” under the Ministry of Health of the Russian Federation

MD, orthopedic surgeon of the department of trauma effects and rheumatoid arthritis.

Konstantin Alexandrovich Afonichev

FSBI “Scientific and Research Institute for Children’s Orthopedics n. a. G. I. Turner” under the Ministry of Health of the Russian Federation

Email: afonichev@list.ru
MD, PhD, DMedSc, scientific chief of the department of trauma effects and rheumatoid arthritis.

References

  1. Алексеева Е. И., Литвицкий П. Ф. Ювенильный ревматоидный артрит: этиология, патогенез, клиника, алгоритмы диагностики и лечения: рук. для врачей, преподавателей, науч. сотр. Под общ. ред. A. A. Баранова. М.: Веди, 2007. 360 c. [Alekseeva E.I., Litvitskiy P.F. Juvenile rheumatoid arthritis: etiology, pathogenesis, clinic, diagnostic algorithms and treatment. M.: Vedi, 2007:360.]
  2. Кузьмина Н. Н., Салугина С. О., Никишина И. П. Ювенильный артрит. XXI век. Как мы сегодня понимаем терминологические и классификационные аспекты. Научно-практическая ревматология. 2006. № 4. С. 86-96. [Kuzmina NN, Salugina S.O., Nikishina I.P. Juvenile arthritis of the XXI century. As we today understand terminology and classification aspects. Scientific-practical rheumatology. 2006;(4):86-96.]
  3. Никишина И. П. Диагностика ювенильных спондилоартритов: классификационный и нозологический подходы. Consilium Medicum. 2008. № 2(2). С. 10-13. [Nikishina I.P. Diagnosis of juvenile spondyloarthropathies: classification and nosological approaches. Consilium Medicum. 2008;(2):10-13.]
  4. Новик Г. А., Абакумова Л. Н., Летенкова Н. М., Слизовский Н. В., Слизовская Н. Н. Ювенильные артриты - опыт диагностики и лечения. Лечащий врач. 2008. № 4. С. 23-27. [Novik G.A., Abakumova L.N., Letenkova N.M., Slizovskiy N.V., Slizovskaya N.N. Juvenile arthritis - experience in diagnosis and treatment. Treating physician. 2008;(4):23-27.]
  5. Avcin T., Cimaz R., Falcini F. et al. Prevalence and clinical significance of anti-cyclic citrullinated peptide antibodies in juvenile idiopathic arthritis. Ann Rheum Dis. 2002;(61):608
  6. Bader-Meunier B., Wouters C., Job-Deslandre C. et al. Guidelines for diagnosis and treatment of oligoarticular and polyarticular juvenile idiopathic arthritis. Arch. Pediatr. 2010;17(7):1085-1089.
  7. Behrens E.M., Beukelman T., Gallo L. et al. Evaluation of the presentation of systemic onset juvenile rheumatoid arthritis: data from the Pennsylvania systemic onset juvenile arthritis registry (PASOJAR). Journal of Rheumatology. 2008;35:343-348.
  8. Cassidy J.T., Petty R.E. Juvenile rheumatoid arthritis. In: Textbook of pediatric rheumatology. 4th ed. [Cassidy J.T., Petty R.E. (Eds)], Saunders W.B. Company, Philadelphia. 2001;233.
  9. Cimaz R., Lehman T.J.A., Asherson R. Children with juvenile idiopathic arthritis. J. Rheumatol. 2003;30(4):825-828.
  10. Fisher Corinne, Ioannou Yiannis, Hall-Craggs Margaret et al. Enthesitis Related Arthritis; a New Era of Understanding. Annals of Paediatric Rheumatology. 2012;(1):8-16.
  11. Dorfman H.D., Czerniak B., editors. Bone tumors. St. Louis: Mosby, 1998;85-127.
  12. Elhail M., Wipffl J., Bazeli R. et al. Radiological cervical spine involvement in young adults with polyarticular juvenile idiopathic arthritis. Rheumatology (Oxford). 2013;52(2):267-275.
  13. Ezra D.B., Cohen E., Maftzir G. Uveitis in children and adolescents. Br J Ophthalmol. 2005;(89):444-448.
  14. Habiba H.M., Shaheenb D.A., Elsedfyc G.O. et al. Clinical, laboratory and radiological predictors of extension of oligoarticular juvenile idiopathic arthritis: a prospective study. Int J Clin Pediatr. 2012;(1):76-81.
  15. Hahn Y.S., Kim J.G. Pathogenesis and clinical manifestations of juvenile rheumatoid arthritis. Korean J Pediatr. 2010;53(11):921-930.
  16. Gutierrez K. Bone and Joint Infections in Children. Pediatr Clin N Am. 2005;(52):779-794
  17. Kim K.H., Kim D.S. Juvenile idiopathic arthritis: Diagnosis and differential diagnosis. Korean J Pediatr. 2010;(53):931-935.
  18. Letson D., Falcone R., Muro-Cacho C.A. Pathologic and radiologic feauters of primary bone tumors. Cancer Control Journal. 1999;6(3):283-293.
  19. Nistala K., Woo P., Wedderburn L.R. Juvenile idiopathic arthritis. In: Firestein GS, Budd RC, Harris ED, McInnes I.B., Ruddy S., Sergent J.S., editors. Kelley’s textbook of rheumatology. 8th ed. Philadelphia: Saunders Elsevier, 2008;1657-1676.
  20. Packham J.C., Hall M.A. Long-term follow-up of 246 adults with juvenile idiopathic arthritis: functional outcome. Oxford Journals Medicine Rheumatology. 2002;(41):1428-1435.
  21. Phelan J.D., Thompson S.D. and Glass D.N. Susceptibility to JRA/JIA: complementing general autoimmune and arthritis traits. Genes and Immunity. 2006;(7):1-10.
  22. Prabhu A.S., Bala S. Approach to a child with monoarthritis. Indian J Pediatr. 2010;(77):997-1004.
  23. Ravelli A. Macrophage activation syndrome. Current Opinion in Rheumatology. 2002;(14):548-552.
  24. Ravelli A., Varnier G.C., Oliveira S. et al. Antinuclear antibody positive patients should be grouped as a separate category in the classification of juvenile idiopathic arthritis. Arthritis Rheum. 2011;(63):267-275.
  25. St’ephan J.L., Kon’e-Paut I., Galambrun C. et al. Reactive haemophagocytic syndrome in children with inflammatory disorders. A retrospective study of 24 patients. Rheumatology. 2001;(11):1285-1292.
  26. Thomson W. and Donn R. Juvenile idiopathic arthritis genetics-what’s new? What’s next? Arthritis Res. 2002;(4):302-306.

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

Copyright (c) 2014 Kozhevnikov A.N., Pozdeeva N.A., Konev M.A., Selizov V.V., Prokopovich E.V., Nikitin M.S., Moskalenko A.V., Afonichev K.A.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ № ФС77-54261 от 24 мая 2013 г.


This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies