儿童长管状骨缺损的置换：显微外科腓骨片移植（系统综述）

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详细

材料和方法。文章在以下数据库中进行检索：eLibrary、PubMed和Google Scholar，检索时间范围为10年（2012-2022年（含），最后一次查询时间为2022年11月8日）。俄语搜索引擎的关键词为 “儿童骨缺损置换”和“儿童腓骨骨移植”。英文搜索引擎的关键词为“microsurgical and fibula”、“microvascular and fibula”、“bone and defect”。在对已发表的研究进行分类后， 对17篇印刷论文进行了分析。

结果。根据文献数据，在此期间有690名患者使用腓骨碎片作为自体移植物接受了治疗（平均年龄为12±2.6岁）。缺损形成的最常见原因是恶性肿瘤（647名患者，占93.7%）。在所有病例中，良性病变占0.9%，骨髓炎占2.0%，先天性病变占2.17%，外伤占1.45%。平均随访时间为4.8±2.4年。癌症患者的存活率高达78.4%。作者指出，大量并发症主要来自受术区，占所有不良反应（457例）的85.3%。 在供体部位发现的并发症占14.7%。最常见的是移植物骨折或移植物骨水平骨折，占所有并发症的33.5%。

结论。文献数据分析显示，使用供血腓骨片替代不同性质的大面积骨缺损非常有效，且长期效果良好。尽管存在多种并发症，但这种技术可提供一步到位的肢体重建。腓骨显微外科自体移植的决定取决于外科医生的偏好和手术经验。

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作者简介

Ekaterina A. Zakharyan

H. Turner National Medical Research Center for Children’s Orthopedics and Trauma Surgery

Email: zax-2008@mail.ru
ORCID iD: 0000-0001-6544-1657
SPIN 代码: 4851-9908
Scopus 作者 ID: 57193258044

MD, PhD, Cand. Sci. (Med.)

俄罗斯联邦, Saint Petersburg

Bagauddin H. Dolgiev

H. Turner National Medical Research Center for Children’s Orthopedics and Trauma Surgery

Email: dr-b@bk.ru
ORCID iD: 0000-0003-2184-5304
SPIN 代码: 2348-4418

MD, Orthopedic and Trauma Surgeon

俄罗斯联邦, Saint Petersburg

Nikolay G. Chigvariya

H. Turner National Medical Research Center for Children’s Orthopedics and Trauma Surgery; North-Western State Medical University named after I.I. Mechnikov

Email: chigvariya72@mail.ru
ORCID iD: 0000-0003-4842-7639

MD, PhD, Cand. Sci. (Med.)

俄罗斯联邦, Saint Petersburg; Saint Petersburg

Denis Yu. Grankin

H. Turner National Medical Research Center for Children’s Orthopedics and Trauma Surgery

Email: grankin.md@gmail.com
ORCID iD: 0000-0001-8948-9225
SPIN 代码: 1940-3837

MD, Research Associate

俄罗斯联邦, Saint Petersburg

Konstantin A. Afonichev

H. Turner National Medical Research Center for Children’s Orthopedics and Trauma Surgery; North-Western State Medical University named after I.I. Mechnikov

Email: afonichev@list.ru
ORCID iD: 0000-0002-6460-2567
SPIN 代码: 5965-6506

MD, PhD, Dr. Sci. (Med.)

俄罗斯联邦, Saint Petersburg; Saint Petersburg

Yuriy E. Garkavenko

H. Turner National Medical Research Center for Children’s Orthopedics and Trauma Surgery; North-Western State Medical University named after I.I. Mechnikov

Email: yurijgarkavenko@mail.ru
ORCID iD: 0000-0001-9661-8718
SPIN 代码: 7546-3080
Scopus 作者 ID: 57193271892

MD, PhD, Dr. Sci. (Med.)

俄罗斯联邦, Saint Petersburg; Saint Petersburg

Anastasia I. Arakelyan

H. Turner National Medical Research Center for Children’s Orthopedics and Trauma Surgery

Email: a_bryanskaya@mail.ru
ORCID iD: 0000-0002-3998-4954
SPIN 代码: 9224-5488
Scopus 作者 ID: 57193271649

MD, PhD, Cand. Sci. (Med.)

俄罗斯联邦, Saint Petersburg

Aleksandr P. Pozdeev

H. Turner National Medical Research Center for Children’s Orthopedics and Trauma Surgery; North-Western State Medical University named after I.I. Mechnikov

编辑信件的主要联系方式.
Email: prof.pozdeev@mail.ru
ORCID iD: 0000-0001-5665-6111
SPIN 代码: 3408-8570
Scopus 作者 ID: 6701438186
Researcher ID: T-6146-2018

MD, PhD, Dr. Sci. (Med.), Professor

俄罗斯联邦, Saint Petersburg; Saint Petersburg

参考

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