羟基磷灰石基纳米材料在儿童创伤和骨科层状化学组装条件下的应用前景

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综述了含有羟基磷灰石的纳米材料的层层化学组装方法,并对其在解决一些生物医学问题中的有效性进行了评估。这些方法都是基于使用试剂的吸附在衬底表面的合成顺序的化学反应,
使其可以给定成分的涂料适用于复杂形状的产品,在分子水平上控制涂层的厚度和修改表面
特征,包括粗糙度、亲水性和表面电荷。同时也接收由有机和无机物混合组成的《人工》构造的多层材料。综述中引用的实验材料令人信服地证明了使用逐层化学组装技术来创建新的3D支架的有效性,其目标是修复丢失或受损的骨组织、金属植入物表面涂层和靶向药物传递系统。
以离子取代羟基磷灰石为试剂的层状化学组装技术的发展是这一领域的一个有发展前景的
领域。这一方向的成功将为生物医学的重大成就铺平道路,并为创造新一代的模拟骨矿物相的结构、组成和力学性能的结构提供巨大机会。

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作者简介

Aleksandra Meleshko

Institute of Chemistry St. Petersburg State University

编辑信件的主要联系方式.
Email: alya_him@mail.ru
ORCID iD: 0000-0002-7010-5209

PhD in Technical Sciences, Researcher

俄罗斯联邦, 198504, St. Petersburg, Petergof, Universitetskii prospect 26

Valeri Tolstoy

Institute of Chemistry St. Petersburg State University

Email: v.tolstoy@spbu.ru
ORCID iD: 0000-0003-3857-7238

D.Sc. in Chemistry, senior researcher, Professor

俄罗斯联邦, 198504, St. Petersburg, Petergof, Universitetskii prospect 26

Gennady Afinogenov

Saint Petersburg State University

Email: gennady-afinogenov@yandex.ru
ORCID iD: 0000-0003-1273-7651

MD, PhD, D.Sc., Professor, Professor of the Department of Oral and Maxillofacial Surgery and Surgical Dentistry

俄罗斯联邦, 7/9, Universitetskaya embankment, Saint-Petersburg, 199034

Aleksandra Levshakova

Institute of Chemistry, Saint Petersburg State University

Email: sashkeens@gmail.com
ORCID iD: 0000-0001-8164-5174

graduate student

俄罗斯联邦, 198504, St. Petersburg, Petergof, Universitetskii prospect 26

Anna Afinogenova

Saint Petersburg State University; Saint Petersburg Pasteur Research Institute of Epidemiology and Mictobiology

Email: spbtestcenter@mail.ru
ORCID iD: 0000-0001-8175-0708

Professor of the Department of Oral and Maxillofacial Surgery and Surgical Dentistry; D.Sc. in Biology, Senior Research Associate

俄罗斯联邦, 7/9, Universitetskaya embankment, Saint-Petersburg, 199034; 14, Mira street, Saint Petersburg, 197101

Vladislav Muldiyarov

H. Turner National Medical Research Center for Сhildren’s Orthopedics and Trauma Surgery

Email: Muldiyarov@inbox.ru
ORCID iD: 0000-0002-3988-7193

MD, Clinical Resident

俄罗斯联邦, 64, Parkovaya str., Saint-Petersburg, Pushkin, 196603

Sergei Vissarionov

H. Turner National Medical Research Center for Сhildren’s Orthopedics and Trauma Surgery

Email: vissarionovs@gmail.com
ORCID iD: 0000-0003-4235-5048

MD, PhD, D.Sc., Professor, Corresponding Member of RAS, Deputy Director for Research and Academic Affairs, Head of the Department of Spinal Pathology and Neurosurgery

俄罗斯联邦, 64, Parkovaya str., Saint-Petersburg, Pushkin, 196603

Stanislav Linnik

North-Western State Medical University named after I.I. Mechnikov

Email: stanislavlinnik@mail.ru
ORCID iD: 0000-0002-4840-6662

MD, PhD, D.Sc., Professor, Professor of the Department of traumatology and orthopedics

俄罗斯联邦, 41, Kirochnaya street, Saint-Petersburg, 191015

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