Urology reports (St. - Petersburg)Urology reports (St. - Petersburg)Урологические ведомостиUrology reports (St. - Petersburg)2225-90742687-1416Eco-Vector9055410.17816/uroved90554ReviewsНаучные обзорыReviewsReview ArticlePhotodynamic methods of treatment of nonmuscular-invasive bladder cancerФотодинамические методы лечения немышечно-инвазивного рака мочевого пузыря非光动力治疗非侵入性膀胱癌的方法KasymovBahtijar G.КасымовБахтияр ГалыулыKasymovBahtijar G.
Kazakhstan

Urologist

Врач-уролог

Urologist

b_kasymov@bk.ru6224-3395ShanazarovNasrulla A.ШаназаровНасрулла АбдуллаевичShanazarovNasrulla A.
Kazakhstan

Dr. Sci. (Med.), Professor, Oncologist

д-р мед. наук, профессор, врач-онколог

Dr. Sci. (Med.), Professor, Oncologist

nasrulla@inbox.ruMuratovTimur M.МуратовТимур МуратулыMuratovTimur M.
Kazakhstan

Cand. Sci. (Med.), Urologist

канд. мед. наук, врач-уролог

Cand. Sci. (Med.), Urologist

ttimeke@mail.ruDaniyarovaGulnur D.ДанияроваГулнур ДанияркызыDaniyarovaGulnur D.
Kazakhstan

Specialist of the Center for Robotic Surgery

специалист Центра роботизированной хирургии

Specialist of the Center for Robotic Surgery

gulnur_011091@mail.ruZhumakayevAkylbek M.ЖумакаевАкылбек МуратбековичZhumakayevAkylbek M.
Kazakhstan

Urologist, Oncologist

Врач-уролог, врач-онколог

Urologist, Oncologist

Akylbek_89@mail.ruhttps://orcid.org/0000-0003-1050-6198571961241486806-7913KyzlasovPavel S.КызласовПавел СергеевичKyzlasovPavel S.
Russian Federation

Dr. Sci. (Med.)

д-р мед. наук

Dr. Sci. (Med.)

dr.kyzlasov@mail.ruhttps://fmbafmbc.ru/centers/urology/https://orcid.org/0000-0002-4108-40665053-0440KazheraAnastasia A.КажераАнастасия АндреевнаKazheraAnastasia A.
Russian Federation

Urologist

врач-уролог

Urologist

Kazhera@inbox.ruhttps://orcid.org/0000-0002-4911-6018571961172119602-7775SlesarevskayaMargarita N.СлесаревскаяМаргарита НиколаевнаSlesarevskayaMargarita N.
Russian Federation

Cand. Sci. (Med.)

канд. мед. наук

Cand. Sci. (Med.)

mns-1971@yandex.ruhttps://www.1spbgmu.ru/ru/universitet/strustura/kafedry/106-glavnaya/3905-slesarevskaya-margarita-nikolaevnahttps://orcid.org/0000-0002-7724-7832568786813002684-4070KuzminIgor V.КузьминИгорь ВалентиновичKuzminIgor V.
Russian Federation

Dr. Sci. (Med.), Professor

д-р мед. наук, профессор

Dr. Sci. (Med.), Professor

kuzminigor@mail.ruhttps://www.1spbgmu.ru/ru/obrazovanie/kafedry/106-glavnaya/3828-igor-valentinovich-kuzminhttps://orcid.org/0000-0002-4857-054265064232202041-8837Al-ShukriSalman Kh.Аль-ШукриСальман ХасуновичAl-ShukriSalman Kh.
Russian Federation

Doc. Sci. (Med.), Professor

д-р мед. наук, профессор

Doc. Sci. (Med.), Professor

alshukri@mail.ruMedical Centre Hospital of President’s affairs administration of the Republic of KazakhstanБольница Медицинского центра Управления Делами Президента Республики Казахстан на праве хозяйственного веденияMedical Centre Hospital of President’s affairs administration of the Republic of KazakhstanMultidisciplinary medical center of the akimat of the city of Nur-SultanМногопрофильный медицинский центр акимата города Нур-СултанMultidisciplinary medical center of the akimat of the city of Nur-SultanBurnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency of RussiaМедико-биологический университет инноваций и непрерывного образования Государственного научного центра «Федеральный медицинский биофизический центр им. А.И. Бурназяна»Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency of RussiaAcademician I.P. Pavlov First St. Petersburg State Medical UniversityПервый Санкт-Петербургский государственный медицинский университет им. акад. И.П. ПавловаAcademician I.P. Pavlov First St. Petersburg State Medical University16122021151220211143553631512202116122021Copyright ©; 2021, Kasymov B.G., Shanazarov N.A., Muratov T.M., Daniyarova G.D., Zhumakayev A.M., Kyzlasov P.S., Kazhera A.A., Slesarevskaya M.N., Kuzmin I.V., Al-Shukri S.K.Copyright ©; 2021, Касымов Б.Г., Шаназаров Н.А., Муратов Т.М., Даниярова Г.Д., Жумакаев А.М., Кызласов П.С., Кажера А.А., Слесаревская М.Н., Кузьмин И.В., Аль-Шукри С.Х.Copyright ©; 2021, Kasymov B.G., Shanazarov N.A., Muratov T.M., Daniyarova G.D., Zhumakayev A.M., Kyzlasov P.S., Kazhera A.A., Slesarevskaya M.N., Kuzmin I.V., Al-Shukri S.K.2021Kasymov B.G., Shanazarov N.A., Muratov T.M., Daniyarova G.D., Zhumakayev A.M., Kyzlasov P.S., Kazhera A.A., Slesarevskaya M.N., Kuzmin I.V., Al-Shukri S.K.Касымов Б.Г., Шаназаров Н.А., Муратов Т.М., Даниярова Г.Д., Жумакаев А.М., Кызласов П.С., Кажера А.А., Слесаревская М.Н., Кузьмин И.В., Аль-Шукри С.Х.Kasymov B.G., Shanazarov N.A., Muratov T.M., Daniyarova G.D., Zhumakayev A.M., Kyzlasov P.S., Kazhera A.A., Slesarevskaya M.N., Kuzmin I.V., Al-Shukri S.K.https://creativecommons.org/licenses/by-nc-nd/4.0/https://journals.eco-vector.com/uroved/article/view/90554

The review article is devoted to the application of photodynamic therapy for non-muscle invasive bladder cancer. The data on the mechanism and pathogenetic bases of the application of this method of treatment, the method of its implementation, the advantages and disadvantages of the photosensitizers and the results of clinical studies are presented. It has been shown that intraoperative photodynamic therapy significantly reduces the rate of recurrence of bladder cancer after transurethral resection, including in patients with carcinoma in situ and multifocal growth of urothelial tumors.

Обзорная статья посвящена применению фотодинамической терапии немышечно-инвазивного рака мочевого пузыря. Приведены данные о механизме и патогенетических основах применения данного метода лечения, методике его проведения, преимуществах и недостатках используемых фотосенсибилизаторов, представлены результаты клинических исследований. Показано, что интраоперационное проведение фотодинамической терапии существенно снижает частоту рецидивирования рака мочевого пузыря после трансуретральной резекции простаты, в том числе у пациентов с carcinoma in situ и при мультифокальном росте уротелиальных опухолей.

本文就光动力学在非肌层浸润性膀胱癌诊断中的应用作一综述。本文介绍了这种治疗方法的机理和发病基础、实施方法、所用光敏剂的优缺点以及临床研究结果。已经表明，术中光动力疗法显着降低了经尿道前列腺切除术后膀胱癌复发的发生率，包括carcinoma in situ和尿路上皮肿瘤多灶性生长的患者。

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