HERALD of North-Western State Medical University named after I.I. MechnikovHERALD of North-Western State Medical University named after I.I. Mechnikov2618-71162618-9704Eco-Vector1119710.17816/mechnikov20191125-12Research ArticleElectroencephalographic arousal pattern in severe alcohol poisoningAleksandrovMikhail V.mdoktor@yandex.ruPovalyukhinaEkaterina S.mdoktor@yandex.ruAlexandrovaTatyana V.tata-al@yandex.ruIvanovLev B.mdoktor@yandex.ruChernyiValery S.9297911@list.ruRussian Neurosurgery Research Institute named after prof. A.L. Polenov (branch of the Almazov National Medical Research Center)Institute of toxicology of Federal Medical-Biological AgencyDzhanelidze Research Institute of Emergency MedicineMoscow City Clinical Hospital № 9 of G.N. SperanskyMilitary Medical Academy named after S.M. Kirov090820191125122402201919032019Copyright © 2019, Aleksandrov M.V., Povalyukhina E.S., Alexandrova T.V., Ivanov L.B., Chernyi V.S.2019<p style="text-align: justify;">Parameters dynamics of brain bioelectric activity of 50 patients in alcoholic coma are considered. Patients underwent continuous EEG monitoring from the end of the basic resuscitation to the apparent recovery of consciousness (awakening). The average registration time was 4.5 hours. EEG was recorded in standard derivations using the 1020 system. The amplitude-frequency indices of spontaneous activity and reactivity are analyzed. Electroencephalographic correlates of cerebral insufficiency in comatose states are distinguished by pronounced polymorphism and high individual variability. Considering these features, dynamic parameters should be used as prognostic criteria: spontaneity and variability of the pattern, reactivity during stimulation. The increase in the frequency of bioelectric activity, desynchronization with external stimuli may indicate the beginning of the process of recovery of consciousness. Electrophysiological criteria for awakening, developed in this work on the example of alcoholic coma, can be mostly applicable to unconscious states caused by other etiological factors: trauma, hypoxia, vascular failure.</p>acute poisoningalcoholic comabioelectric brain activityelectroencephalographyarousal patternострое отравлениеалкогольная комабиоэлектрическая активность головного мозгаэлектроэнцефалографияпаттерн пробуждения[Белкин А.А., Зислин Б.Д., Аврамченко А.А. и др. Синдром острой церебральной недостаточности как концепция нейрореаниматологии // Анестезиология и реаниматология. – 2008. – № 2. – С. 4–8. [Belkin AA, Zislin BD, Avramchenko AA et al. Acute cerebral insufficiency syndrome as a concept of neu-roreanimatology. Russian Journal of Anаеsthesiology and Reanimatology. 2008; 2: 4–8. 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