HERALD of North-Western State Medical University named after I.I. MechnikovHERALD of North-Western State Medical University named after I.I. Mechnikov2618-71162618-9704Eco-Vector928710.17816/mechnikov201810299-106Research ArticleBiological tissue reaction to the intracorporeally-polymerising implant used in a minimally invasive “puncture-infusion-seal” method of the inguinal canalTruninE. M.<p>Department of Operative and Clinical Surgery with Topographical Anatomy</p>mjaweed10@hotmail.comMowlabucusM. J.<p>Department of Operative and Clinical Surgery with Topographical Anatomy</p>mjaweed10@hotmail.comMurtL. L.<p>Department of Operative and Clinical Surgery with Topographical Anatomy</p>mjaweed10@hotmail.comSmirnovA. A.<p>Department of Operative and Clinical Surgery with Topographical Anatomy</p>mjaweed10@hotmail.comTatarkinV. V.<p>Department of Operative and Clinical Surgery with Topographical Anatomy</p>mjaweed10@hotmail.comRybakovV. A.<p>Department of Operative and Clinical Surgery with Topographical Anatomy</p>mjaweed10@hotmail.comNorth-Western State Medical University named after I.I. Mechnikov150720181029910607082018Copyright © 2018, Trunin E.M., Mowlabucus M.J., Murt L.L., Smirnov A.A., Tatarkin V.V., Rybakov V.A.2018<p>The article focuses on the study of the biological properties of a synthetic intracorporeally-polymerising implant, designed to be used in a minimally invasive puncture-infusion-seal technique under experimental study for the treatment of reducible inguinal hernias. The method is innovative in the field of herniology and surgery in general for its minimal invasiveness. Two types of experiments were conducted to investigate the response of live tissues of the body to the implant as a foreign body (on rats) and the impact of the implant on the male reproductive system of rabbits.</p>polymercopolymerhydrogelsintracroporeally-polymerising implantherniaminimally invasive methods in the treatment of inguinal herniasimmune response to foreign bodiesполимерсополимергидрогелиинтракорпорально-полимеризующийся имплантатгрыжамини-инвазивные методы лечения паховых грыжответная реакция организма на инородные тела[Должиков А.А., Колпаков А.Я., Ярош А.Л., и др. Гигантские клетки инородных тел и тканевые реакции на поверхности имплантатов // Курский научно-практический вестник «Человек и его здоровье». - 2017. - Т. 3. - C. 86-94. [Dolzhikov AA, Kolpakov AY, Yarosh AL, et al. Giant foreign body cells and tissue reactions on the surface of implants. Kurskii nauchno-prakticheskii vestnik “Chelovek i ego zdorov’e”. 2017;(3):86-94. 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