Pheochromocytoma in combination with severe aortic insufficiency: clinical case

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详细

Pheochromocytoma is a rare neuroendocrine tumor of the adrenal medulla with widespread cardiac complications. Dilation of the heart chambers can cause valve defects. At the same time, severe cardiac comorbid conditions that complicate the choice of treatment tactics for patients are not sufficiently described in the literature. A clinical case of pheochromocytoma in combination with severe aortic insufficiency in a man admitted to the endocrinology department is presented. In conditions of aortic insufficiency, the risk of surgical intervention is extremely high. After a thorough analysis of clinical and laboratory-instrumental data, the patient was recommended to have a right-sided laparoscopic adrenalectomy.

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作者简介

Sergey Shustov

North-Western State Medical University named after I.I. Mechnikov; Kirov Military Medical Academy

Email: Sergei.Shustov@szgmu.ru
ORCID iD: 0000-0002-9075-8274
SPIN 代码: 5237-2036

MD, Dr. Sci. (Med.), Professor

俄罗斯联邦, 41 Kirochnay St., Saint Petersburg, 191015; Saint Petersburg

Zulfiya Shafigullina

North-Western State Medical University named after I.I. Mechnikov

Email: zulfiya.shafigullina@szgmu.ru
ORCID iD: 0000-0001-8292-8504
SPIN 代码: 7569-3823

MD, Cand. Sci. (Med.)

俄罗斯联邦, 41 Kirochnay St., Saint Petersburg, 191015

Anna Vydrych

North-Western State Medical University named after I.I. Mechnikov

编辑信件的主要联系方式.
Email: an.vidrih@mail.ru
ORCID iD: 0009-0006-9667-3454
SPIN 代码: 7301-8482

MD, Cand. Sci. (Med.)

俄罗斯联邦, 41 Kirochnay St., Saint Petersburg, 191015

Aleksandr Lisitsyn

North-Western State Medical University named after I.I. Mechnikov

Email: aleksandr.lisitsyn@szgmu.ru
ORCID iD: 0000-0003-2045-0044
SPIN 代码: 3237-4309

MD, Cand. Sci. (Med.)

俄罗斯联邦, 41 Kirochnay St., Saint Petersburg, 191015

Alisa Semenova

Kirov Military Medical Academy

Email: foxberry451@gmail.com
ORCID iD: 0000-0002-0809-3681

MD, clinical resident

俄罗斯联邦, Saint Petersburg

参考

  1. Mokhort TV, Velesevich EI, Mokhort EG. Pheochromocytoma: new approaches to diagnosis and management. Mezhdunarodnye obzory: klinicheskaya praktika i zdorov’e. 2016;(1):4–23. EDN: VKQONP
  2. Santos JRU, Brofferio A, Viana B, Pacak K. Catecholamine-induced cardiomyopathy in pheochromocytoma: how to manage a rare complication in a rare disease? Horm Metab Res. 2019;51(7):458–469. doi: 10.1055/a-0669-9556
  3. Beltsevich DG, Kuznetsov AB, Lysenko MA, et al. Catecholamine-induced cardiomyopathy in patients with pheochromocytoma. Endocrine surgery. 2013;7(1):16–22. EDN: RTQBLP doi: 10.14341/serg2013116-22
  4. Yang L, Hennis L, Patel K, Saccocci MA. Laparoscopic adrenalectomy of pheochromocytoma following management of severe aortic stenosis with transcatheter aortic valve replacement under monitored anesthesia care sedation: a case report. BMC Anesthesiol. 2023;23(1):18. doi: 10.1186/s12871-023-01977-6
  5. Feinstein I, Lee T, Khan S, et al. A case report of an open aortic valve replacement followed by open adrenalectomy in a patient with symptomatic pheochromocytoma and critical aortic stenosis. J Cardiothorac Surg. 2021;16(1):282. doi: 10.1186/s13019-021-01665-x
  6. Haase M, Dringenberg T, Allelein S, et al. Excessive catecholamine secretion and the activation of the renin-angiotensin-aldosterone system in patients with pheochromocytoma: a single center experience and overview of the literature. Horm Metab Res. 2017;49(10):748–754. doi: 10.1055/s-0043-117179
  7. Thompson LDR. Pheochromocytoma of the Adrenal gland Scaled Score (PASS) to separate benign from malignant neoplasms: a clinicopathologic and immunophenotypic study of 100 cases. Am J Surg Pathol. 2002;26(5):551–566. doi: 10.1097/00000478-200205000-00002

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2. Figure. Macroscopic sample of the removed right adrenal gland

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