Progress in using the drugs based on hydrobionts in treatment of respiratory viral infections and their complications

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Abstract


The data of possibilities to use biologically active compounds, peptides and polysaccharides in particular, from sea urchins as potent sources of drugs are represented in the article. Their ability to act on the main chains of pathogenesis of the respiratory viral infections has been shown. So peptides and polysaccharides possess anti-inflammatory action due to inhibition of cyclooxygenase and inhibition of MAP kinase p38 phosphorylation, as well as antioxidant, immune correcting, antiviral and antibacterial effects. The progress in searching new drugs based on glycopeptides from sea urchins for treatment of respiratory tract infections and their complications are discussed.


Anastasiya E. Katelnikova

Author for correspondence.
spbpharm@mail.ru
Saint Petersburg Institute of Pharmacy
Russian Federation, Leningrad region, Russia

researcher

Valerii G. Makarov

spbpharm@mail.ru
Saint Petersburg Institute of Pharmacy
Russian Federation, Leningrad region, Russia

DrSci (Medicine), professor, general director

Victoria V. Vorobieva

v.v.vorobeva@mail.ru
Smolensk State Medical University
Russian Federation, Smolensk, Russia

DrSci (Medicine), professor, department of pharmacology

Olga N. Pozharitskaya

olgapozhar@mail.ru
Saint Petersburg Institute of Pharmacy
Russian Federation, Leningrad region, Russia

PhD (Pharmacy), senior researcher, head of department of new technologies and standardization, depute of general director

Alexander N. Shikov

alexs79@mail.ru
Saint Petersburg Institute of Pharmacy
Russian Federation, Leningrad region, Russia

DrSci (Pharmacy), senior researcher, depute of general director

Petr D. Shabanov

pdshabanov@mail.ru
S.M. Kirov Military Medical Academy
Russian Federation, Saint Petersburg, Russia

Dr Med Sci (Pharmacology), Professor and Head, Dept. of Pharmacology

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