Congenital hypertrophy of the retinal pigment epithelium
- Authors: Cherney E.1
-
Affiliations:
- Vanderbilt Eye Institute
- Issue: Vol 6, No 4 (2013)
- Pages: 55-59
- Section: Articles
- Submitted: 24.06.2015
- Published: 15.12.2013
- URL: https://journals.eco-vector.com/ov/article/view/366
- DOI: https://doi.org/10.17816/OV2013455-59
- ID: 366
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Abstract
Congenital hypertrophy of the retinal pigment epithelium is a benign pigmented lesion of the posterior pole with a unique clinical appearance. It is flat, round, and has sharp edges. While it is usually black, it may have internal lacunae without pigment. The lesion may also be all hypopigmented. Over many years, the lesions may grow slightly and change their pigmentation. Even though malignant transformation is extremely rare, annual examinations should be performed.
About the authors
Edward Cherney
Vanderbilt Eye Institute
Email: edward.cherney@Vanderbilt
Edu Associate Professor of Ophthalmology
References
- Reese A. B., Jones I.S. Benign melanomas of the retinal pigment epithelium // Am J. Ophthalmology. - 1956. - Vol. 42. - P. 207.
- Buettner H. Congenital hypertrophy of the retinal pigment epithelium (RPE) A nontumorous lesion // Mod Probl. Ophthalmol. - 1974. - Vol. 12. - P. 528.
- Shields J. A., Augsburger J. J., Brown G. C., Stephens R. F. The differential diagnosis of posterior uveal melanoma // Ophthalmology. - 1980. - Vol. 87. - P. 518-522.
- Coleman P. Barnard N. A. Congenital hypertrophy of the retinal pigment epithelium: prevalence and ocular features in the optometric population // Ophthalmic Physiol Opt. - 2007. - Vol. 27, N 6. - P. 547-555.
- Augsbuger J. J., Henson G. L., Hershbergeer V. S. Trichopoupos N. Topographical distribution of typical unifocal congenital hypertrophy of retinal pigment epithelium 2006 Graefes // Arch. Clin. Exp. Ophthal. - 2006. - Vol. 224. - P. 1412-1414.
- Buettner H. Congenital hypertrophy of the retinal pigment epithelium // Am. J. Ophthal. - 1975. - Vol. 79. - P. 177-189.
- Shields C. L., Mashayekhi A., Ho T. et al. Solitary congenital hypertrophy of the retinal pigment epithelium. Clinical features and frequency of enlargement in 330 patients // Ophthalmology. - 2003. - Vol. 110. - P. 1968-1976.
- Chamot L., Zografos L., Klainguti G. Fundus changes associated with congenital hypertrophy of the retinal pigment epithelium // AM J. Ophthal. - 1993. - Vol. 115. - P. 154-161.
- Shields J. A., Shields C. L., Singh A. D. Acquired tumors arising from congenital hypertrophy of the retinal pigment epithelium // Arch. Ophthalmol. - 2000. - Vol. 118. - P. 637-641.
- Lloyd W. C., Eagle R. C., Shields J. A. et al. Congential Hypertrophy of the Pigment Epithelium Electron Microscopic and morphometric Observations // Ophthalmology. - 1990. - Vol. 97. - P. 1052-1060.
- Cleary P. E., Gregor Z., Bird A. C. Retinal vascular changes in congenital hypertrophy of the retinal pigment epithelium // Brit. J. Ophthal. - 1976. - Vol. 60. - P. 499-503
- Cohen S. Y., Quentel G., Guiberteau B., Coscas G. J. Retinal vascular changes in congenital hypertrophy of the retinal pigment epithelium. Ophthalmology. - 1993. - Vol. 100, N 4. - P. 471-474.
- Shields C. L., Pirondini C., Bianciotto C., Harmon S. A., Shields J. A. Autofluorescence of congenital hypertrophy of the retinal pigment epithelium // Retina. - 2007. - Vol. 27, N 8. - P. 1097-1100.
- Shields C. L., Materin M. A., Walker C., Marr B. P., Shields J. A. Photoreceptor loss overlying congenital hypertrophy of the retinal pigment epithelium by optical coherence tomography // Ophthalmology. - 2006. - Vol. 113, N 4. - P. 661-665.
- Sorsby A. Congenital coloboma of the macula // Br. J Ophthal. - 1935. - Vol. 19. - P. 65-90.