The influence of phacoemulsification on various corneal layers in patients with pseudoexfoliation syndrome assessed with confocal in vivo microscopy

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Phacoemulsification (PHACO) is the basic procedure of cataract extraction.

Purpose. To assess the impact of PHACO on corneal epithelium layers in patients with pseudoexfoliation syndrome (PEX) by confocal in vivo microscopy.

Methods. 24 patients with PEX syndrome and 18 patients without it were enrolled in the prospective study. In vivo confocal microscopy was performed with assessment of cellular density in corneal epithelial layers, degree of its desquamation, degree of Bowman membrane stiffening and dendritic cells density.

Results. The epithelial cells density didn’t change significantly in groups. Confocal microscopy showed high density of dendritic cells and marked desquamation of the epithelium in patients with PEX (p < 0,05) after PHACO.

Vitaly V. Potemkin

Author for correspondence.
Ophthalmologic Center of Saint Petersburg State Hospital No 2
Russian Federation, Saint Petersburg


Tatyana S. Varganova
Ophthalmologic Center of Saint Petersburg State Hospital No 2
Russian Federation, Saint Petersburg


Irina V. Terekhova
Ophthalmologic Center of Saint Petersburg State Hospital No 2
Russian Federation, Saint Petersburg

Chief of Ophthalmology diagnostic department

Elena V. Ageeva
Ophthalmologic Center of Saint Petersburg State Hospital No 2
Russian Federation, Saint Petersburg


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