Mutually reinforcing triad: depression, erectile dysfunction and cardiovascular pathology in men


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Abstract

The combination of depression, erectile dysfunction (ED), and cardiovascular disease, more often - arterial hypertension, is called as a mutually reinforcing triad. Associated pathology increases the risk of premature death, worsens the prognosis and reduced social functioning of patients. The common pathogenic mechanisms of ED, depression and hypertension are endothelial dysfunction with decreased nitric oxide, low levels of androgens, the violation of cortico-visceral connections with the imbalance of the hypothalamic-pituitary-adrenal system and sympathicotonia. Complex pathophysiology requires prescription of adequate antihypertensive and psychotherapy, effective treatment of erectile dysfunction.

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About the authors

E. Petrova

Penza State University

Email: petrovaelena2010@yandex.ru
Candidate of Medical Sciences

N. Herzog

Regional Clinical Hospital at the Penza Station OAO «RZhD»

Email: petrovaelena2010@yandex.ru
Penza

G. Baranova

Penza State University

Email: petrovaelena2010@yandex.ru
Candidate of Medical Sciences

E. Nesterenko

Penza State University

Email: petrovaelena2010@yandex.ru
Candidate of Historical Science

T. Maltseva

Penza State University

Email: petrovaelena2010@yandex.ru

T. Koldova

Regional Clinical Hospital at the Penza Station OAO «RZhD»

Email: petrovaelena2010@yandex.ru
Penza

P. Poluboyarinov

Penza State University of Architecture and Construction

Email: petrovaelena2010@yandex.ru
Candidate of Agricultural Sciences

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