The pattern of neurological syndromes in patients with HIV-associated brain diseases


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

The case histories of 111 patients with HIV-associated brain diseases who died during the period in 2016 to 2019 were retrospectively analyzed. According to the nosologies of HIV-associated brain diseases, the author identified the following groups of patients without HIV-associated brain diseases: meningoencephalitis; tuberculous brain lesion; combined brain lesion; cerebral toxoplasmosis; HIV-associated encephalopathy; and cerebral lymphoma. Meningeal syndrome and general cerebral symptoms were found to be prevalent among all neurological syndromes. In particular, moderate meningeal syndrome prevailed among the patients with meningeal syndrome and stupor among those with depression of consciousness. Among motor and cognitive impairments, there was a preponderance of moderate and severe disorders. Convulsive syndrome was most rarely noted. The groups with meningoencephalitis, tuberculous brain lesion, or combined brain lesions showed the largest number of cases with meningeal syndrome and general cerebral symptoms. The cerebral toxoplasmosis group was observed to have the highest rates of pyramidal syndrome, speech disorders, cranial nerve damage, and pelvic organ dysfunctions.

Full Text

Restricted Access

About the authors

A. V Kaplitsky

V.F. Dolgopolov Vyselki Central District Hospital

Email: fardor@mail.ru
Vyselki Stanitsa, Krasnodar Territory

References

  1. Пирогова И.А. Распространенность ВИЧ-инфекции в России. Вестник совета молодых ученых и специалистов Челябинской области. 2017; 4 (19): 45-9 [Pirogova I. A. The prevalence of HIV infection in Russia. Vestnik soveta molodykh uchenykh i spetsialistov Chelyabinskoi oblasti. 2017; 4 (19): 45-9 (in Russ.)].
  2. Ратникова Л.И., Шип С.А., Глинкина А.А. и др. ВИЧ-инфекции и инфекционные поражения центральной нервной системы. Инфекционные болезни. 2016; 14 (S1): 242 [Ratnikova L.I., Ship S.A., Glinkina A.A. et al. HIV infections and infectious lesions of the Central nervous system. Infectious diseases. 2016; 14 (S1): 242 (in Russ.)].
  3. Густов А.В., Руина Е.А., Шилов Д.В. и др. Клинические варианты поражения нервной системы при ВИЧ-инфекции. Клиническая медицина. 2010; 3: 61-5 [Gustov A.V., Ruina E.A., Shilov D.V. et al. Clinical variants of the nervous system lesion at a HIV-infection. Clinical medicine. 2010; 3: 61-5 (in Russ.)].
  4. Завалишина И.А., Спирина Н.Н., Бойко А.Н. и др. Хронические нейроинфекции. М.: ГЭОТАР-Медиа, 2017 [Zavalishina I.A., Spirina N.N., Boyko A.N. et al. Chronic neuroinfections. M.: GEOTAR-Media, 2017 (in Russ.)].
  5. Беляков Н.А., Медведев С.В., Трофимова Т.Н. и др. Механизмы поражения головного мозга при ВИЧ-инфекции. Вестник РАМН. 2012; 9: 4-12 [Belyakov N.A., Medvedev S.V., Trofimova T.N. et al. Mechanisms of cerebral damage in patients with HIV-infection. Annals of the Russian academy of medical sciences. 2012; 9: 4-12 (in Russ.)]. doi: 10.15690/vramn.v67i9.400
  6. Евзельман М.А. и др. Неврологические осложнения ВИЧ-инфекции. Журнал неврологии и психиатрии им. С.С. Корсакова. 2015; 115 (3): 89-93 [Evzel'man M.A. et al. Neurological disorders associated with HIV-infection. S.S. Korsakov Journal of Neurology and Psychiatry. 2015; 115 (3): 89-93 (in Russ.)]. https://doi.org/10.17116/jnevro20151153189-93
  7. Шоломова Е.И., Ребров К.А., Шоломов И.И. Вторичные заболевания у пациентов с ВИЧ-обусловленной неврологической патологией. Саратовский научно-медицинский журнал. 2016; 12 (3): 388-90 [Scholomova E.I., Rebrov K.A., Sholomov 1.1. Comorbid diseases at patients with HIV-induced neurological disorders. Saratov J Med Sci Res. 2016; 12 (3): 388-90 (in Russ.)].

Supplementary files

Supplementary Files
Action
1. JATS XML

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies