Multifaceted coronavirus

The paper deals with the study and generalization of literature data on the clinical manifestations of a novel coronavirus infection. SARS-CoV-2 has been identified in most countries, but scientists do not know much about it. Physicians constantly face the patients who present difficulties in diagnosis and therapy. The spread of COVID-19 has raised questions for physicians about the definition of the aspects, diagnosis, and management tactics for patients with this disease. SARS-CoV-2 extends rapidly through the body, affecting the respiratory system with the development of pneumonia, acute respiratory failure. The pathogenesis of COVID-19 is mediated by angiotensin converting enzyme-2 receptors. Settling in the body, the virus affects various human organs and systems. The patients can experience a wide range of symptoms, including headaches, muscle aches, fatigue, diarrhea, mental confusion, arrhythmias, seizures, loss of appetite, dyspnea, and many other conditions. However, the disease is asymptomatic or has mild symptoms (mild malaise and low-grade fever) in many infected people. SARS-CoV-2 begins to destroy the body from the upper respiratory tract, attacks the lower respiratory tract, subsequently affecting the heart and blood vessels, gastrointestinal tract, kidneys, skin, central and peripheral nervous systems. Damage to the internal organs can be so serious that it can lead to death. Currently, information about the epidemiology, clinical features, prevention and treatment of this disease is formed by specialists from different countries, but much remains unexplored. Most experts believe that we have seen only the «tip of the iceberg». This means that the world has faced the poorly understood, dangerous disease that changes its forms and manifestations.

infectious diseases, coronavirus, lungs, blood vessels, heart, kidneys, nervous system, skin