Diagnosis and treatment of familial Mediterranean fever (periodic disease)
- Authors: Skvortsov V.V1, Statsenko I.Y.1, Kirina M.A2, Golieva E.A1, Malyakin G.I1
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Affiliations:
- Volgograd State Medical University, Ministry of Health of Russia
- Volgograd Regional Clinical Hospital One
- Issue: Vol 33, No 1 (2022)
- Pages: 73-77
- Section: Articles
- URL: https://journals.eco-vector.com/0236-3054/article/view/114565
- DOI: https://doi.org/10.29296/25877305-2022-01-12
- ID: 114565
Cite item
Abstract
Familial Mediterranean fever (FMF; periodic disease) is an autosomal recessive disease, the features of which are recurrent inflammatory episodes, abdominal pain, fever, and arthritis. FMF is divided into two phenotypes. The most accurate diagnostic method is molecular genetic testing that includes a single-gene study, utilization of a multigene panel, and more whole- genome testing. The main therapy for the disease includes colchicine; its acute episodes are treated with nonsteroidal anti-inflammatory drugs and infusion therapy. Drugs, such as anakinra, rilonacept, and canakinumab, are used to treat colchicine-resistant FMF patients. The article describes the clinical case of a female patient with FMF.
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About the authors
V. V Skvortsov
Volgograd State Medical University, Ministry of Health of Russia
Email: vskvortsov1@ya.ru
Associate Professor
Russian Federation,I. Yu Statsenko
Volgograd State Medical University, Ministry of Health of Russia
Email: vskvortsov1@ya.ru
Associate Professor
Russian Federation,M. A Kirina
Volgograd Regional Clinical Hospital One
Email: vskvortsov1@ya.ru
Russian Federation,
E. A Golieva
Volgograd State Medical University, Ministry of Health of Russia
Email: vskvortsov1@ya.ru
Russian Federation,
G. I Malyakin
Volgograd State Medical University, Ministry of Health of Russia
Author for correspondence.
Email: vskvortsov1@ya.ru
Russian Federation,
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