Langerhans cell histiocytosis of the temporal bones: a clinical case
- Authors: Diab K.M.1, Daikhes N.A1, Saidulaev V.A1, Yunusov A.S1, Pashinina O.A1, Mikhalevich A.E1
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Affiliations:
- National Medical Research Center of Otorhinolaryngology, Federal Biomedical Agency of Russia
- Issue: Vol 33, No 1 (2022)
- Pages: 78-80
- Section: Articles
- URL: https://journals.eco-vector.com/0236-3054/article/view/114566
- DOI: https://doi.org/10.29296/25877305-2022-01-13
- ID: 114566
Cite item
Abstract
Langerhans cell histiocytosis (LCH) is a rare disease with an incidence of 1 to 9 cases per 1,000,000 population per year. From 75 to 90% of cases of the disease occur in childhood. The etiology of the disease is unknown. Pathogenetically, the disease is characterized by a clonal proliferation of Langerhans cells - the lymphoid dendritic cells originating from the bone marrow have an antigen-presenting function outside the dermis. The temporal bones are affected in 2530% of cases. The disease is more common in males. The peak incidence occurs in the first 3 years of life. The disease can be asymptomatic for a long time or be masked as other common middle ear pathologies (chronic suppurative otitis media, mastoiditis, and otitis externa). The article describes a clinical case of temporal bone LCH. The feature of the clinical case in the recurrent course of the disease is that it is masked as acute mastoiditis.
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About the authors
Kh. M.-A Diab
National Medical Research Center of Otorhinolaryngology, Federal Biomedical Agency of Russia
Email: sultan070487@mail.ru
Professor
Russian Federation,N. A Daikhes
National Medical Research Center of Otorhinolaryngology, Federal Biomedical Agency of Russia
Email: sultan070487@mail.ru
Corresponding Member of the Russian Academy of Sciences, Professor
Russian Federation,V. A Saidulaev
National Medical Research Center of Otorhinolaryngology, Federal Biomedical Agency of Russia
Email: sultan070487@mail.ru
Candidate of Medical Sciences
Russian Federation,A. S Yunusov
National Medical Research Center of Otorhinolaryngology, Federal Biomedical Agency of Russia
Email: sultan070487@mail.ru
Professor
Russian Federation,O. A Pashinina
National Medical Research Center of Otorhinolaryngology, Federal Biomedical Agency of Russia
Email: sultan070487@mail.ru
Candidate of Medical Sciences
Russian Federation,A. E Mikhalevich
National Medical Research Center of Otorhinolaryngology, Federal Biomedical Agency of Russia
Author for correspondence.
Email: sultan070487@mail.ru
Candidate of Medical Sciences
Russian Federation,References
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