New coronavirus infection: clinical and pathogenetic aspects, prevention, importance of vitamins and trace elements
- Authors: Dedov D.V1,2
-
Affiliations:
- Tver State Medical University
- Tver Regional Clinical Cardiology Dispensary
- Issue: Vol 33, No 2 (2022)
- Pages: 47-49
- Section: Articles
- URL: https://journals.eco-vector.com/0236-3054/article/view/114574
- DOI: https://doi.org/10.29296/25877305-2022-02-07
- ID: 114574
Cite item
Abstract
The article presented the results of studies from the United Kingdom, the People’s Republic of China, Germany, South Korea, Iran, the United States, Norway, the Russian Federation, France, and Greece. Reflected clinical and pathogenetic aspects of a new coronavirus infection (COVID-19). Showed associations of vitamin and micronutrient deficiencies with weakening of the immune system, defense against viruses. Revealed correlations of COVID-19 severity and decreased serum concentrations of calcium, iron, zinc. We recognized the connection of selenium deficiency in food, deficiency of this microelement in organism with increase of risk of infection, risk of COVID-19 complications. We found a direct correlation between selenium content and blood oxygen saturation in COVID-19 patients. Inverse correlation was found between selenium content and body temperature, severity of lung damage, C-reactive protein concentration. We noted the value of SELENBIO selenium-containing complex for women in the correction of vitamin and micronutrient deficiencies, strengthening the immune system and thus preventing complications of COVID-19 coronavirus infection.
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About the authors
D. V Dedov
Tver State Medical University; Tver Regional Clinical Cardiology Dispensary
Author for correspondence.
Email: dedov_d@inbox.ru
Professor
References
- Авдеев С.Н., Адамян Л.В., Алексеева Е.И. и др. Профилактика, диагностика и лечение новой коронавирусной инфекции (COVID-19): Временные методические рекомендации. М.: Министерство здравоохранения Российской Федерации, 2021; 233 с.
- Драпкина О.М., Дроздова Л.Ю., Авдеев С.Н. и др. Оказание амбулаторнополиклинической медицинской помощи пациентам с хроническими заболеваниями, подлежащим диспансерному наблюдению, в условиях пандемии COVID-19. Временные методические рекомендации. версия 2. Кардиоваскулярная терапия и профилактика. 2021; 20 (8): 245-90 doi: 10.15829/1728-8800-2021-3172
- Shakoor H., Feehan J., Al Dhaheri A.S. et al. Immune-boosting role of vitamins D., C., E., zinc, selenium and omega-3 fatty acids: Could they help against COVID-19? Maturitas. 2021; 143: 1-9. doi: 10.1016/j.maturitas.2020.08.003
- Hoffmann C., Wolf E. Older age groups and country-specific case fatality rates of COVID-19 in Europe, USA and Canada. Infection. 2021; 49 (1): 111-6. doi: 10.1007/s15010-020-01538-w
- Barazzoni R., Bischoff S.C., Busetto L. et al. Nutritional management of individuals with obesity and COVID-19: ESPEN expert statements and practical guidance. Clin Nutr. 2021: S0261-5614(21)00248-X. doi: 10.1016/j.clnu.2021.05.006
- Keam S., Megawati D., Patel S.K. et al. Immunopathology and immunotherapeutic strategies in severe acute respiratory syndrome coronavirus 2 infection. Rev Med Virol. 2020; 30 (5): e2123. doi: 10.1002/rmv.2123
- Глыбочко П.В., Фомин В.В., Авдеев С.Н. и др. Клиническая характеристика 1007 больных тяжелой SARS-CoV-2 пневмонией, нуждавшихся в респираторной поддержке. Клиническая фармакология и терапия. 2020; 29 (2): 21-9 doi: 10.32756/0869-5490-2020-2-21-29
- Berger M.M., Herter-Aeberli I., Zimmermann M.B. et al. Strengthening the immunity of the Swiss population with micronutrients: A narrative review and call for action. Clin Nutr ESPEN. 2021; 43: 39-48. doi: 10.1016/j.clnesp.2021.03.012
- Bermano G., Meplan C., Mercer D.K. et al. Selenium and viral infection: are there lessons for COVID-19? Br J. Nutr. 2021; 125 (6): 618-27. DOI: 10.1017/ S0007114520003128
- Yang C., Yao H., Wu Y. et al. Status and risks of selenium deficiency in a traditional selenium-deficient area in Northeast China. Sci Total Environ. 2021; 762: 144103. doi: 10.1016/j.scitotenv.2020.144103
- Xu Y., Hao Z., Li Y. et al. Distribution of selenium and zinc in soil-crop system and their relationship with environmental factors. Chemosphere. 2020; 242: 125289. doi: 10.1016/j.chemosphere.2019.125289
- Pecora F., Persico F., Argentiero A. et al. The Role of Micronutrients in Support of the Immune Response against Viral Infections. Nutrients. 2020; 12 (10): 3198. doi: 10.3390/nu12103198
- Zhang H.Y., Zhang A.R., Lu Q.B. et al. Association between fatality rate of COVID-19 and selenium deficiency in China. BMC Infect Dis. 2021; 21 (1): 452. doi: 10.1186/s12879-021-06167-8
- Notz Q., Herrmann J., Schlesinger T. et al. Clinical Significance of Micronutrient Supplementation in Critically Ill COVID-19 Patients with Severe ARDS. Nutrients. 2021; 13 (6): 2113. doi: 10.3390/nu13062113
- Im J.H., Je Y.S., Baek J. et al. Nutritional status of patients with COVID-19. Int J. Infect Dis. 2020; 100: 390-3. doi: 10.1016/j.ijid.2020.08.018
- Richardson D.P., Lovegrove J.A. Nutritional status of micronutrients as a possible and modifiable risk factor for COVID-19: a UK perspective. Br J. Nutr. 2021; 125 (6): 678-84. doi: 10.1017/S000711452000330X
- Calder P.C. Foods to deliver immune-supporting nutrients. Curr Opin Food Sci. 2022; 43: 136-45. doi: 10.1016/j.cofs.2021.12.006
- Hybsier S., Schulz T., Wu Z. et al. Sex-specific and inter-individual differences in biomarkers of selenium status identified by a calibrated ELISA for selenoprotein P. Redox Biol. 2017; 11: 403-14. doi: 10.1016/j.redox.2016.12.025
- Gorji A., Khaleghi Ghadiri M. Potential roles of micronutrient deficiency and immune system dysfunction in the coronavirus disease 2019 (COVID-19) pandemic. Nutrition. 2021; 82: 111047. doi: 10.1016/j.nut.2020.111047
- Steinbrenner H., Speckmann B., Klotz L.O. Selenoproteins: Antioxidant selenoenzymes and beyond. Arch Biochem Biophys. 2016; 595: 113-9. doi: 10.1016/j.abb.2015.06.024
- Skalny A.V., Timashev P.S., Aschner M. et al. Serum Zinc, Copper, and Other Biometals Are Associated with COVID-19 Severity Markers. Metabolites. 2021; 11 (4): 244. doi: 10.3390/metabo11040244
- Дедов Д.В. Селен и селенсодержащие препараты: значение для организма и профилактики различных заболеваний. Фармация. 2021; 70 (8): 54-7. DOI: 10/29296/25419218-2021-08-09
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