IMPACT OF COGNITIVE IMPAIRMENT ON THE PREVALENCE AND COURSE OF GERIATRIC SYNDROMES

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Abstract

Cognitive decline is one of the main geriatric syndromes associated with early loss of independence, as well as an increased risk of developing other geriatric syndromes and mortality in old age. The aim of the study To assess the prevalence of cognitive decline and its impact on the prevalence and course of major geriatric syndromes in community-dwelling older adults aged 65 and over. Materials and methods A random sample of 611 people aged 65 and over. The observation time was 2.5years. Methods: Comprehensive geriatric assessment. Results Mild cognitive impairment was found in 180 (44.4%) of the participants, mild dementia in 91 (14.9%), moderate dementia in 59 (9.7%), and severe dementia in 10 (1.6%). The decline in cognitive functions in old age was associated with an increase in the prevalence of the main geriatric syndromes: malnutrition, physical decline, urinary incontinence, depression, sarcopenia, and frailty. The dynamics of changes in cognitive functions was associated with an increase or decrease in the risk of progression of other geriatric syndromes. Conclusio All patients with cognitive impairment should be actively screened for other geriatric syndromes. Also, patients with other geriatric syndromes need to carry out a mandatory assessment of the level of cognitive functions. Correcting nutritional status, treating depression, and increasing physical activity are potentially modifiable risk factors for cognitive decline in old age.

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About the authors

A. V Turusheva

I.I. Mechnikov North-Western State Medical University

Email: anna.turusheva@gamil.com

E. V Frolova

I.I. Mechnikov North-Western State Medical University

Email: anna.turusheva@gamil.com

доктор медицинских наук, профессор

T. A Bogdanova

I.I. Mechnikov North-Western State Medical University

Author for correspondence.
Email: anna.turusheva@gamil.com

References

  1. Ткачева О.Н., Котовская Ю.В., Рунихина Н.К. и др. Клинические рекомендации «Старческая астения». Российский журнал гериатрической медицины. 2020; 1: 11-46. doi: 10.37586/2686-8636-1-2020-11-46
  2. Общероссийская общественная организация «Российская ассоциация геронтологов и гериатров» - Общественная организация «Российское общество психиатров». Клинические рекомендации: Когнитивные расстройства у лиц пожилого и старческого возраста. 2020; 317.
  3. Комплексная междисциплинарная и межведомственная программа профилактики, раннего выявления, диагностики и лечения когнитивных расстройств у лиц пожилого и старческого возраста до 2025 г., 2018.
  4. Folstein M.F., Folstein S.E., McHugh P.R. «Mini-mental state». A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975; 12 (3): 189-98. doi: 10.1016/0022-3956(75)90026-6
  5. Koen A.P., LemminkH.K., Mathieu H.G. de Greef at al. Reliability of the Groningen Fitness Test for the Elderly. J Aging Phys Act. 2001; 9: 194-212.
  6. Turusheva A., Frolova E, Degryse J.M. Age-related normative values for handgrip strength and grip strength’s usefulness as a predictor of mortality and both cognitive and physical decline in older adults in northwest Russia. J Musculoskelet Neuronal Interact. 2017; 17 (1): 417-32.
  7. Turusheva A., Frolova E., Hegendoerfer E et al. Predictors of short-term mortality, cognitive and physical decline in older adults in northwest Russia: a population-based prospective cohort study. Aging Clin Exp Res. 2017; 29 (4): 665-73. doi: 10.1007/s40520-016-0613-7
  8. Bauer S., Lambert M.J., Nielsen S.L. Clinical significance methods: a comparison of statistical techniques. JPersAssess. 2004; 82 (1): 60-70. doi: 10.1207/s15327752jpa8201_11
  9. Шлепцова М.В., Фролова Е.В. Распространенность основных гериатрических синдромов в практике врача-гериатра амбулаторного этапа и возможности их коррекции. Российский семейный врач. 2018; 22 (2): 30-6. doi: 10.17816/RFD2018230-36
  10. Tripathi M., Vibha D. Reversible dementias. Indian J Psychiatry. 2009; 51 (Suppl. 1): S52-S55.
  11. Турушева А., Фролова Е. Взаимосвязь депрессии и когнитивных нарушений в российской популяции лиц старше 65 лет: результаты исследования «Хрусталь». Врач. 2018; 9: 26-30. doi: 10.29296/25877305-2018-09-06
  12. Verghese J., Lipton R.B., Hall C.B. et al. Abnormality of gait as a predictor of non-Alzheimer's dementia. N Engl J Med. 2002: 347 (22): 1761-8. doi: 10.1056/NEJMoa020441
  13. Aggarwal N.T., Wilson R.S., Beck T.L. et al. Motor dysfunction in mild cognitive impairment and the risk of incident Alzheimer disease. Arch Neurol. 2006; 63 (12): 1763-9. doi: 10.1001/archneur.63.12.1763
  14. Inzitari M., Baldereschi M., Di Carlo A. et al. Impaired attention predicts motor performance decline in older community-dwellers with normal baseline mobility: results from the Italian Longitudinal Study on Aging (ILSA). J Gerontol A Biol Sci Med Sci. 2007; 62 (8): 837-43. doi: 10.1093/gerona/62.8.837
  15. Mirelman A., Herman T., Brozgol M. et al. Executive function and falls in older adults: new findings from a five-year prospective study link fall risk to cognition. PLoS One. 2012; 7 (6): e40297. doi: 10.1371/journal.pone.0040297
  16. Clouston S.A., Brewster P., Kuh D. et al. The dynamic relationship between physical function and cognition in longitudinal aging cohorts. Epidemiol Rev. 2013; 35 (1): 33-50. doi: 10.1093/epirev/mxs004
  17. Verghese J., Wang C., Lipton R.B. et al. Motoric cognitive risk syndrome and the risk of dementia. J Gerontol A Biol Sci Med Sci. 2013; 68 (4): 412-8. doi: 10.1093/gerona/ gls191
  18. Gheysen F., Poppe L., DeSmet A. Physical activity to improve cognition in older adults: can physical activity programs enriched with cognitive challenges enhance the effects? A systematic review and meta-analysis.Int J Behav Nutr Phys Act. 2018; 15 (1): 63. doi: 10.1186/s12966-018-0697-x
  19. Scarmeas N., Anastasiou C.A., Yannakoulia M. Nutrition and prevention of cognitive impairment. Lancet Neurol. 2018; 17 (11): 1006-15. doi: 10.1016/S1474-4422(18)30338-7
  20. Турушева А.В. Распространенность синдрома недержания мочи и его взаимосвязь с показателями физического и психического здоровья у пожилых людей по данным исследований «Хрусталь» и «Эвкалипт». Российский семейный врач. 2021; 25 (2): 29-37. doi: 10.17816/RFD71196
  21. Cesari M., Araujo de Carvalho I. et al. Evidence for the Domains Supporting the Construct of Intrinsic Capacity. J Gerontol A Biol Sci Med Sci. 2018; 73 (12): 1653-60. doi: 10.1093/gerona/gly011

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