IMPACT OF AUTOIMMUNE INFLAMMATION ON THE DEVELOPMENT OF ATHEROSCLEROSIS IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS
- Authors: Shilkina N.1, Savina Z.1, Yunonin I.1, Masina I.1
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Affiliations:
- Yaroslav State Medical Academy
- Issue: Vol 23, No 10 (2012)
- Pages: 56-59
- Section: Articles
- URL: https://journals.eco-vector.com/0236-3054/article/view/115581
- ID: 115581
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Open Access
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Abstract
The arterial wall was compared in patients with systemic lupus erythematosus (SLE) or in those with hypertensive disease. In the SLE group, systemic inflammatory activity was rated using the SLEDAI and ECLAM scales. All the patients underwent 24-hour blood pressure monitoring, by calculating the values of vascular wall rigidity during daylight and nocturnal hours, by estimating desquamated endotheliocytes in the Goryaev chamber, by determining plasma endothelin-1, and by performing duplex Doppler ultrasound of the cervical vessels. There was a relationship between decreased arterial elasticity and increased endothelial dysfunction in patients with SLE. The findings suggest that chronic autoimmune inflammation affects the higher values of vascular wall rigidity.
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About the authors
N. Shilkina
Yaroslav State Medical Academy
Email: shilkin39@mail.ru
Professor, MD
Zh. Savina
Yaroslav State Medical Academy
I. Yunonin
Yaroslav State Medical AcademyCandidate of Medical Sciences
I. Masina
Yaroslav State Medical AcademyCandidate of Medical Sciences
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