Methods of assessing the quality of life in women with malignant neoplasms of the reproductive system

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Abstract

The growth of malignant neoplasms of the female reproductive system in recent years has acquired a tendency to "rejuvenation" – more frequent appearance in women of reproductive age. Radical methods of treating pathologies of the oncogynecological spectrum leave severe consequences in the form of genitourinary syndrome, disorders of endocrine-metabolic processes, sexual function, unstable psychological state, social maladaptation and a decrease in the quality of life. To restore the effects of antitumor treatment, a comprehensive rehabilitation is required, developed by a multidisciplinary team of specialists, including questionnaires on the quality of life. Numerous studies have shown the effectiveness of questionnaires FACT-G, FACT-En, EORTC, FSFI, HADS, the health, activity, mood questionnaire, modified Kupperman–Uvarova menopausal index, MDQ, magnesium deficiency assessment test, stress tolerance self-assessment test. These questionnaires allow us to assess the patient's condition in a timely manner, his perception of his own quality of life and the presence of comorbid diseases and conditions. The introduction of questionnaires into routine clinical practice will make it possible to more effectively carry out rehabilitation measures in oncogynecological patients.

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About the authors

A. G. Solopova

I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia

Email: blinov2010@googlemail.com
ORCID iD: 0000-0002-7456-2386

Doctor of Medical Sciences, Professor

Russian Federation, Moscow

D. V. Blinov

I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia; F.P. Haass Moscow Medical and Social Institute

Author for correspondence.
Email: blinov2010@googlemail.com
ORCID iD: 0000-0002-3367-9844

Candidate of Medical Sciences

Russian Federation, Moscow; Moscow

E. E. Achkasov

I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia

Email: blinov2010@googlemail.com
ORCID iD: 0000-0001-9964-5199

Doctor of Medical Sciences, Professor

Russian Federation, Moscow

L. N. Sandzhieva

I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia

Email: blinov2010@googlemail.com
ORCID iD: 0000-0002-5083-6581
Russian Federation, Moscow

D. I. Korabelnikov

F.P. Haass Moscow Medical and Social Institute

Email: blinov2010@googlemail.com
ORCID iD: 0000-0002-0459-0488

Candidate of Medical Sciences

Russian Federation, Moscow

G. K. Bykovshchenko

I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia

Email: blinov2010@googlemail.com
Russian Federation, Moscow

D. A. Petrenko

I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia

Email: blinov2010@googlemail.com
ORCID iD: 0000-0001-5849-5585
Russian Federation, Moscow

References

  1. Soerjomataram I., Bray F. Planning for tomorrow: global cancer incidence and the role of prevention 2020–2070. Nat Rev Clin Oncol. 2021; 18 (10): 663–72. doi: 10.1038/s41571-021-00514-z
  2. Sung H., Ferlay J., Siegel R.L. et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021; 71 (3): 209–49. doi: 10.3322/caac.21660
  3. Kaprin A.D., Starinskii V.V., Shakhzadova A.O. Zlokachestvennye novoobrazovaniya v Rossii v 2020 godu (zabolevaemost' i smertnost'). M.: MNIOI im. P.A. Gertsena – filial FGBU «NMITs radiologii» Minzdrava Rossii, 2021; 252 р. (in Russ.).
  4. Son J., Carr C., Yao M. et al. Endometrial cancer in young women: prognostic factors and treatment outcomes in women aged ≤40 years. Int J Gynecol Cancer. 2020; 30 (5): 631–9. doi: 10.1136/ijgc-2019-001105
  5. Aune D., Sen A., Vatten L.J. Hypertension and the risk of endometrial cancer: a systematic review and meta-analysis of case-control and cohort studies [published correction appears in Sci Rep. 2018 Apr 06; 8: 46961]. Sci Rep. 2017; 7: 44808. doi: 10.1038/srep44808
  6. Bahado-Singh R.O., Lugade A., Field J. et al. Metabolomic prediction of endometrial cancer. Metabolomics. 2017; 14 (1): 6. doi: 10.1007/s11306-017-1290-z
  7. Coll-de la Rubia E., Martinez-Garcia E., Dittmar G. et al. Prognostic Biomarkers in Endometrial Cancer: A Systematic Review and Meta-Analysis. J Clin Med. 2020; 9 (6): 1900. doi: 10.3390/jcm9061900
  8. Vlasina A.Yu., Solopova A.G., Ivanov A.E. et al. Assessment of early symptoms of surgical menopause in patients with borderline ovarian tumors. Obstetrics, Gynecology and Reproduction. 2020; 14 (3): 269–82 (in Russ.). doi: 10.17749/2313-7347/ob.gyn.rep.2020.125
  9. Klinicheskie rekomendatsii. Pogranichnye opukholi yaichnikov. 2019; 44 р. (in Russ.). URL: https://oncology-association.ru/files/new-clinical-guidelines/pogranichnye_opuholi_jaichnikov.pdf
  10. Klinicheskie rekomendatsii: rak vul'vy, 2022 (in Russ.). URL: http://oncology.ru/specialist/treatment/references/actual/501.pdf
  11. Klinicheskie rekomendatsii Minzdrava Rossii. Rak tela matki i sarkomy matki MKB-10: C54. 2021 (in Russ.).
  12. Falcone F., Laurelli G., Losito S. et al. Fertility preserving treatment with hysteroscopic resection followed by progestin therapy in young women with early endometrial cancer. J Gynecol Oncol. 2017; 28 (1): e2. doi: 10.3802/jgo.2017.28.e2
  13. Solopova A.G., Moskvichyova V.S., Blbulyan T.A. et al. Topical issues of prevention, diagnosis and treatment of vulvar and vaginal cancer. Obstetrics, Gynecology and Reproduction. 2018; 12 (4): 62–70 (in Russ.). doi: 10.17749/2313-7347.2018.12.4.062-070
  14. Makatsariya A.D., Blinov D.V., Bitsadze V.O. et al. Treatment of postmenopausal vulvovaginal atrophy with estriol: a scientific update for 2014–2018. Obstetrics, Gynecology and Reproduction. 2019; 13 (3): 227–38 (in Russ.). doi: 10.17749/2313-7347.2019.13.3.227-238
  15. Solopova A.G., Blinov D.V., Begovich E. et al. Neurological disorders after hysterectomy: from pathogenesis to clinical manifestations. Epilepsy and paroxysmal conditions. 2022; 14 (1): 54–64 (in Russ.). doi: 10.17749/2077-8333/epi.par.con.2022.115
  16. Ampilogova D.M., Solopova A.G., Blinov D.V. et al. Vulvovaginal atrophy: issues of treatment and rehabilitation: A review. Gynecology. 2022; 24 (4): 240–5 (in Russ.). doi: 10.26442/20795696.2022.4.201792
  17. Solopova A.G., Achkasov E.E., Makatsariya A.D. et al. Psycho-emotional profile of patients with vulvar lichen sclerosus. Obstetrics, Gynecology and Reproduction. 2020; 14 (2): 203–10 (in Russ.). doi: 10.17749/2313-7347/ob.gyn.rep.2020.106
  18. Tarasov E.A., Blinov D.V., Zimovina U.V. et al. Magnesium deficiency and stress: Issues of their relationship, diagnostic tests, and approaches to therapy. Ter Arkh. 2015; 87 (9): 114–22 (in Russ.). doi: 10.17116/terarkh2015879114-122
  19. Blinov D.V., Zimovina J.V., Sandakova E.A. et al. Magnesium deficiency of patients with hormone dependent diseases: pharmacoepidemiological profile and life quality assessment. FARMAKOEKONOMIKA. Modern Pharmacoeconomics and Pharmacoepidemiology. 2015; 8 (2): 16–24 (in Russ.). doi: 10.17749/2070-4909.2015.8.2.016-024
  20. Blinov D.V., Ushakova T.I., Makatsariya N.A. et al. Hormonal contraception and magnesium deficiency: a subanalysis of the MAGYN study. Obstetrics, Gynecology and Reproduction. 2017; 11 (1): 36–48 (in Russ.). doi: 10.17749/2313-7347.2017.11.1.036-048
  21. Sandzhieva L.N., Solopova A.G., Blinov D.V. et al. Comparatively analyzed quality of life in patients with atypical endometrial hyperplasia and endometrial cancer during various rehabilitation activities. Obstetrics, Gynecology and Reproduction. 2022; 16 (4): 410–25 (in Russ.). doi: 10.17749/2313-7347/ob.gyn.rep.2022.344
  22. Idrisova L.E., Solopova А.G., Achkasov E.E. et al. Assessment of the impact of rehabilitation on the quality of life of gynaecological oncology patients. Gynecology, Obstetrics and Perinatology. 2019; 18 (6): 41–5 (in Russ.). doi: 10.20953/1726-1678-2019-6-41-45
  23. Solopova A.G., Idrisova L.E., Makatsariya A.D., et al. Multidisciplinary approach to medical rehabilitation of oncogynecologic patients. Obstetrics, Gynecology and Reproduction. 2017; 11 (4): 57–67 (in Russ.). doi: 10.17749/2313-7347.2017.11.4.057-067
  24. Blbulyan T.A., Solopova A.G., Ivanov A.E. et al. Effect of postoperative rehabilitation on quality of life in patients with vulvar cancer. Obstetrics, Gynecology and Reproduction. 2020; 14 (4): 415–25 (in Russ.). doi: 10.17749/2313-7347/ob.gyn.rep.2020.156
  25. Solopova A.G., Vlasina A.Y., Idrisova L.E. et al. Rehabilitation of oncogynecological patients: current problems and possible solutions rehabilitation of oncogynecological patients: current problems and possible solutions. Vestnik vosstanovitel’noy medicini. 2019; 5 (93): 87–96 (in Russ.).
  26. Oprosnik kachestva zhizni Vsemirnoi organizatsii zdravookhraneniya (yadernyi modul') [Elektronnyi resurs] (in Russ.). URL: http://psylab.info
  27. Bonomi A.E., Cella D.D., Hahn E.A. et al. Multilingual translation of the Functional Assessment of Cancer Therapy (FACT) quality of life measurement system. Qual Life Res. 1996; 5 (3): 309–20. doi: 10.1007/BF00433915
  28. Kaasa S., Bjordal K., Aaronson N. et al. (1995). The EORTC core quality of life questionnaire (QLQ-C30): validity and reliability when analysed with patients treated with palliative radiotherapy. Eur J Cancer. 1995; 31A (13-14): 2260–3. doi: 10.1016/0959-8049(95)00296-0
  29. Greimel E., Bottomley A., Cull A. et al. EORTC Quality of Life Group and the Quality of Life Unit (2003). An international field study of the reliability and validity of a disease-specific questionnaire module (the QLQ-OV28) in assessing the quality of life of patients with ovarian cancer. Eur J Cancer. 2003; 39 (10): 1402–08. doi: 10.1016/s0959-8049(03)00307-1
  30. Greimel E., Nordin A., Lanceley A. et al. Psychometric validation of the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-Endometrial Cancer Module (EORTC QLQ-EN24). Eur J Cancer. 2011; 47 (2): 183–90. doi: 10.1016/j.ejca.2010.08.014
  31. Wiegel M., Meston C., Rosen R. The female sexual function index (FSFI): cross-validation and development of clinical cutoff scores. J Sex Marital Ther. 2005; 31 (1): 1–20. doi: 10.1080/00926230590475206
  32. Zigmond A.S., Snaith R.P. The hospital anxiety and depression scale. Acta Psychiatr Scand. 1983; 67 (6): 361–70. doi: 10.1111/j.1600-0447.1983.tb09716.x
  33. Slagle P. Magnificent Magnesium. The Way Up Newsletter. Vol. 30, 08-15-01.
  34. Richter P., Werner J., Heerlein A. et al. On the validity of the Beck Depression Inventory. A review. Psychopathology. 1998; 31 (3): 160–8. doi: 10.1159/000066239
  35. Blinov D.V., Solopova A.G., Plutnitskiy A.N. et al. Strengthening health care to provide rehabilitation services for women with cancer diseases of the reproductive system. FARMAKOEKONOMIKA. Modern Pharmacoeconomics and Pharmacoepidemiology. 2022; 15 (1): 119–30 (in Russ.). doi: 10.17749/2070-4909/farmakoekonomika.2022.132
  36. Vlasina A.V., Idrisova L.E., Solopova A.G. et al. Rehabilitation of oncogynecological patients after antitumor therapy: ways of solution. Obstetrics, Gynecology and Reproduction. 2020; 14 (1): 44–55 (in Russ.). doi: 10.17749/2313-7347.2020.14.1.44-55

Supplementary files

Supplementary Files
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1. JATS XML
2. Stress tolerance self-assessment test [18]

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