A clinical case of morphea associated with Borrelia infection
- Authors: Abo Khadeejeh M.B.1, Olenich I.V.2, Niewozinska Z.A.2, Korsunskaya I.M.3
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Affiliations:
- Peoples’ Friendship University of Russia
- Moscow Research and Practical Center of Dermatovenereology and Cosmetology, Moscow Healthcare Department
- Center for Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences
- Issue: Vol 34, No 8 (2023)
- Pages: 81-84
- Section: From Practice
- URL: https://journals.eco-vector.com/0236-3054/article/view/569092
- DOI: https://doi.org/10.29296/25877305-2023-08-16
- ID: 569092
Cite item
Abstract
Scleroderma is an inflammatory disease that is evident as skin atrophy. The pathogenesis of scleroderma remains not completely understood. It is agreed that this disease arises from vascular changes, impaired fibroblast function, and immune dysfunction. The scientific literature also widely discusses an association between scleroderma and Borrelia infection. To date, there is no consensus regarding the mechanism of the influence of Lyme disease on the development of focal scleroderma. However, multiple cases of its occurrence after tick bites have been described.
The authors want to draw the attention of specialists to this problem, by presenting their own case from practice. A thorough history collection and examination of patients with focal scleroderma are necessary in order to detect Borrelia infection and, conversely, there is a need for the close monitoring of patients with Lyme disease for the timely initiation of therapy for focal scleroderma.
Keywords
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About the authors
M. B. Abo Khadeejeh
Peoples’ Friendship University of Russia
Author for correspondence.
Email: marykor@bk.ru
ORCID iD: 0000-0003-0837-822X
Russian Federation, Moscow
I. V. Olenich
Moscow Research and Practical Center of Dermatovenereology and Cosmetology, Moscow Healthcare Department
Email: marykor@bk.ru
ORCID iD: 0000-0001-5753-2567
Russian Federation, Moscow
Z. A. Niewozinska
Moscow Research and Practical Center of Dermatovenereology and Cosmetology, Moscow Healthcare Department
Email: marykor@bk.ru
ORCID iD: 0000-0002-5913-9635
PhD; Professor
Russian Federation, MoscowI. M. Korsunskaya
Center for Theoretical Problems of Physicochemical Pharmacology, Russian Academy of Sciences
Email: marykor@bk.ru
ORCID iD: 0000-0002-6583-0318
MD, Professor
Russian Federation, MoscowReferences
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