Recurrences and distant metastases after radical subcutaneous and skin-sparing mastectomies with reconstruction for breast cancer
- Authors: Rasskazova E.1, Zikiryakhodzhaev A.D.1,2,3, Kaprin A.D.1,2,3
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Affiliations:
- P.A. Herzen Moscow Oncology Research Institute, Branch, National Medical Radiology Research Center, Ministry of Health of Russia
- I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia
- Peoples’ Friendship University of Russia
- Issue: Vol 34, No 10 (2023)
- Pages: 58-62
- Section: From Practice
- URL: https://journals.eco-vector.com/0236-3054/article/view/623199
- DOI: https://doi.org/10.29296/25877305-2023-10-11
- ID: 623199
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Abstract
The paper presents literature data on oncological results (the features of recurrences and metastases) of subcutaneous or skin-sparing mastectomies with reconstruction for breast cancer (BC). Local recurrences of BC, as well as distant metastases occur in about 75% of cases in the first 5 years after surgery. The risk of recurrences and metastases correlates with the molecular biological type of cancer.
The paper considers the relationship of postoperative radiation therapy after subcutaneous or skin-sparing mastectomies to the risk of a recurrence.
Analyzing the literature data allows conclusions about the low risk of recurrences after skin-sparing/subcutaneous mastectomies with single-stage reconstruction. Local and regional recurrences after these surgical interventions occur if there are poor prognostic factors, including those at Stages IIВ–IIIС of the disease, metastases in the regional lymph nodes, multicentricity, in the absence of radiation therapy, in the presence of HER2 overexpression or triple-negative breast cancer, if the patients are young.
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About the authors
E. Rasskazova
P.A. Herzen Moscow Oncology Research Institute, Branch, National Medical Radiology Research Center, Ministry of Health of Russia
Email: rasskaz2@yandex.ru
ORCID iD: 0000-0003-0307-8252
Candidate of Medical Sciences
Russian Federation, MoscowA. D. Zikiryakhodzhaev
P.A. Herzen Moscow Oncology Research Institute, Branch, National Medical Radiology Research Center, Ministry of Health of Russia; I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia; Peoples’ Friendship University of Russia
Email: rasskaz2@yandex.ru
ORCID iD: 0000-0001-7141-2502
Doctor of Medical Sciences
Russian Federation, Moscow; Moscow; MoscowA. D. Kaprin
P.A. Herzen Moscow Oncology Research Institute, Branch, National Medical Radiology Research Center, Ministry of Health of Russia; I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia; Peoples’ Friendship University of Russia
Author for correspondence.
Email: rasskaz2@yandex.ru
ORCID iD: 0000-0001-8784-8415
Academician of the Russian Academy of Sciences, Doctor of Medical Sciences, Professor
Russian Federation, Moscow; Moscow; MoscowReferences
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