Dilated cardiomyopathy as a clinical model of premature aging in humans

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Abstract

The compliance of dilated cardiomyopathy (DCM) with the requirements of a clinical model of premature aging in humans is substantiated. The pathogenetic basis of the formation of DCM and their relationship with changes associated with myocardial aging are considered.

The study complements and clarifies the understanding of the pathogenetic mechanisms of premature aging of the human body and its clinical models, and also provides the basis for further research into the problem of premature aging of the body and age-related diseases.

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About the authors

K. P. Kravchenko

Saint Petersburg Institute of Bioregulation and Gerontology

Email: dinatrotsyuk@yandex.ru
ORCID iD: 0000-0001-8824-1543
Russian Federation, Saint Petersburg

D. S. Medvedev

Saint Petersburg Institute of Bioregulation and Gerontology

Email: dinatrotsyuk@yandex.ru
ORCID iD: 0000-0001-7401-258X

MD, Professor

Russian Federation, Saint Petersburg

S. N. Morozkina

Saint Petersburg Research Institute of Phthisiopulmonology, Ministry of Health of Russia

Email: dinatrotsyuk@yandex.ru
ORCID iD: 0000-0003-0122-0251

Candidate of Chemical Sciences

Russian Federation, Saint Petersburg

D. V. Trotsyuk

Belgorod State National Research University; Saint Petersburg Medical and Social Institute

Author for correspondence.
Email: dinatrotsyuk@yandex.ru
ORCID iD: 0000-0002-0833-4385
Russian Federation, Belgorod; Saint Petersburg

G. I. Gurko

Saint Petersburg Institute of Bioregulation and Gerontology

Email: dinatrotsyuk@yandex.ru
ORCID iD: 0000-0002-4021-1342

MD

Russian Federation, Saint Petersburg

O. V. Podkaura

S.M. Kirov Military Medical Academy, Ministry of Defense of Russia

Email: dinatrotsyuk@yandex.ru
ORCID iD: 0009-0003-1131-470X

Candidate of Medical Sciences

Russian Federation, Saint Petersburg

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