Review of modern devices for inhalation therapy

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Abstract

Samara State Medical University, Ministry of Health of Russia

Inhalation therapy is the introduction of a medicinal substance directly into the respiratory tract using special inhalers. To date, more than 200 devices for inhalation therapy have been developed. The purpose of the work is to review modern devices for inhalation therapy, to clarify their advantages and disadvantages. Interest in inhalation therapy can be explained by several reasons. Let's list them. First, you can inject the drug directly into the respiratory system. Secondly, the therapeutic effect comes quickly. Thirdly, the drug is almost not absorbed into the blood, so there are no systemic side effects. In addition, the patient can do inhalation independently at home. At the same time, inhalation therapy has several disadvantages. Sometimes it is difficult for the patient to understand how to use the inhaler. The doctor should show, explain and control inhalation. The particle size of the aerosol is very important, as is the patient's inspiratory flow rate.

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About the authors

Е. V. Yakovleva

Samara State Medical University, Ministry of Health of Russia

Author for correspondence.
Email: borodulinbe@yandex.ru
ORCID iD: 0000-0003-1858-5206

Сandidate of Medical Sciences

Russian Federation, Samara

Е. А. Borodulina

Samara State Medical University, Ministry of Health of Russia

Email: borodulinbe@yandex.ru
ORCID iD: 0000-0002-3063-1538

Professor, MD

Russian Federation, Samara

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Supplementary files

Supplementary Files
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1. JATS XML
2. Fig 1. A schematic representation of the oldest known reference of therapeutic aerosol delivery in which smoke of henbane plants was inhaled through the stalk of a reed (c. 1554 BC) [2]

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3. Fig. 2. Mudge Inhaler, schematic (a) and photo (б): when the patient inhaled through the flexible mouthpiece, air was drawn in through the three holes on the handle and passed through the drug solution before exiting the mouthpiece [2]

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