The use of vitamin D preparations taking into account vitamin D-deficient conditions

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Abstract

Currently, much attention is being paid to the status of vitamin D as a biomarker of the general state of human health, since low levels of vitamin D are associated with a wide range of diseases. Vitamin D metabolism is complex. Vitamin D and its containers can have genomic and non-genomic activity.

The article presents the most common causes of vitamin D deficiency. Screening for vitamin D deficiency is shown in groups of patients with risk factors for its development. Individual features of vitamin D influence caused by genetic polymorphism of the VDR gene are described.

For the prevention and treatment of vitamin D-deficient conditions, the use of the vitamin D preparation colecalciferol is recommended. Drugs with high activity calcitriol and alfacalcidol are necessary in certain groups of patients for strict indications, in particular in the complex therapy of osteoporosis.

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About the authors

E. A. Dontsеva

Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Ministry of Health of Russia; Federal Center of Neurosurgery, Ministry of Health of Russia

Author for correspondence.
Email: potupchik_tatyana@mail.ru
ORCID iD: 0000-0001-6560-3820

Candidate of Medical Sciences

Russian Federation, Krasnoyarsk; Novosibirsk

T. V. Potupchik

Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Ministry of Health of Russia

Email: potupchik_tatyana@mail.ru
ORCID iD: 0000-0003-1133-4447

Candidate of Medical Sciences

Russian Federation, Krasnoyarsk

I. V. Gatskikh

Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Ministry of Health of Russia

Email: potupchik_tatyana@mail.ru
ORCID iD: 0000-0001-7631-8056

Candidate of Medical Sciences

Russian Federation, Krasnoyarsk

T. P. Shalda

Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Ministry of Health of Russia

Email: potupchik_tatyana@mail.ru
ORCID iD: 0000-0001-5154-5703
Russian Federation, Krasnoyarsk

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