Botulinum toxin in modern cosmetology practice: from high efficiency to the problem of complications (analysis of clinical observation)

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Abstract

At the present stage, there has been an increase in the popularity of wrinkle correction using botulinum toxin, which is largely due to the quick and long-lasting result of this procedure. The accumulated scientific and practical experience shows that cosmetic injections of botulinum toxin are rarely accompanied by complications. However, due to the high demand for procedures and the significant commercialization of this area, cases of its implementation by persons without proper professional education and using non-certified injectables have become more frequent. This often leads to undesirable consequences of the procedure and late treatment of such patients in specialized medical institutions.

The article focuses on the fact that a prerequisite for this procedure is a high level of qualification of a dermatocosmetologist, the obligatory observance of the injection technique and the use of only certified medical preparations. In order to inform healthcare professionals about this problem, we present our own clinical observations of patients with complications after botulinum toxin injections performed by non-medical personnel.

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About the authors

M. M. Tlish

Kuban State Medical University, Ministry of Heath of Russia

Author for correspondence.
Email: marina@netzkom.ru
ORCID iD: 0000-0001-9323-4604

MD, Professor

Russian Federation, Krasnodar

M. I. Sashko

Kuban State Medical University, Ministry of Heath of Russia

Email: marina@netzkom.ru
ORCID iD: 0000-0002-5127-1519

Candidate of Medical Sciences

Russian Federation, Krasnodar

M. E. Shavilova

Kuban State Medical University, Ministry of Heath of Russia

Email: marina@netzkom.ru
ORCID iD: 0000-0002-5776-6221

Candidate of Medical Sciences

Russian Federation, Krasnodar

Yu. I. Katz

Beauty Alliance South LLC

Email: marina@netzkom.ru
ORCID iD: 0009-0006-5900-7890
Russian Federation, Krasnodar

F. A. Psavok

Kuban State Medical University, Ministry of Heath of Russia

Email: marina@netzkom.ru
ORCID iD: 0000-0002-9556-1956

Candidate of Medical Sciences

Russian Federation, Krasnodar

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Supplementary files

Supplementary Files
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1. JATS XML
2. Fig. 1. Dermal pathologic process on the left (a) and right (б) in patient S. when she came to the clinic 20 days after injections of botulinum toxin type A not certified in Russia and artichoke solution

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3. Fig. 2. Ultrasound findings of the dermal pathologic process of patient S.: focal hypoechogenic masses of round and oval shape with inhomogeneous structure and blurred hyperechogenic contour

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4. Fig. 3. Histologic analysis: a – necrotic areas with foreign material deposits (indicated by the arrow) surrounded by epithelioid cells, macrophages, neutrophils, and plasmocytes, ×100; б – foreign material deposits in the form of particles of different size (indicated by the arrow), ×400; hematoxylin-eosin staining

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5. Fig. 4. Dermal pathologic process on the left (a) and right (б) in patient S. after 9 months of therapy

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