Efficacy of metformin and sibutramine therapy in patients with infertility associated with metabolic syndrome

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Abstract

The increasing interest of the scientific medical community in the problem of metabolic syndrome (MS), its timely diagnosis and treatment, is associated with a steady increase in the incidence of MS. The most alarming thing is that the majority of patients are people of active work-related and reproductive age. According to scientists, the frequency of MS is expected to increase by 50% in the next 20 years, which means that in the absence of effective prevention and treatment of MS, industrialized countries risk facing a social and demographic catastrophe. In addition to non-drug treatments for MS (diet, exercise, etc.), metformin and sibutramine are recognized as extremely important drugs of choice in the medical treatment of MS.

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About the authors

М. N. Martina

Palliative Care Center of Department of Health Care of Moscow

Author for correspondence.
Email: rchilova@gmail.com
Russian Federation, Moscow

R. А. Chilova

I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)

Email: rchilova@gmail.com
ORCID iD: 0000-0001-6331-3109

Professor, MD

Russian Federation, Moscow

Е. А. Sokova

Scientific Center for the Examination of Medical Products, Ministry of Health of Russia

Email: rchilova@gmail.com
ORCID iD: 0000-0002-6389-2099

Associate Professor, Candidate of Medical Sciences

Russian Federation, Moscow

S. S. Maslov

I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)

Email: rchilova@gmail.com
ORCID iD: 0009-0007-1215-1059
Russian Federation, Moscow

М. V. Poznyak

I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)

Email: rchilova@gmail.com
ORCID iD: 0009-0006-8217-0784
Russian Federation, Moscow

G. Е. Sevastyanov

I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)

Email: rchilova@gmail.com
Russian Federation, Moscow

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