Prevention of osteoporotic fractures in the elderly


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

Osteoporosis by medical and social significance is in fourth place among noncommunicable diseases. Fractures often have a multifactorial nature. Prevention of fractures in the elderly consists of the prophylaxis and drug therapy of low bone density, the prevention of falls using regular physical exercises, the organization of a safe environment, the correction of treatment regimens for concomitant diseases, excluding drugs that increase the risk of falls, giving up bad habits (smoking, alcohol), balanced nutrition. In a review of the literature, primary and secondary prophylaxis of fractures in the elderly using pharmacological and nonpharmacological agents is considered.

Full Text

Restricted Access

About the authors

S. V Bulgakova

Samara State Medical University

Email: osteoporosis63@gmail.com
MD

E. V Treneva

Samara State Medical University

Email: osteoporosis63@gmail.com
Candidate of Medical Sciences

N. O Zakharova

Samara State Medical University

Email: osteoporosis63@gmail.com
Professor, MD

P. I Romanchuk

Samara State Medical University

Email: osteoporosis63@gmail.com
Candidate of Medical Sciences

References

  1. Nakasato Y., Raymond L. Yung Geriatric Rheumatology. A Comprehensive Approach. 2011; 330 р.
  2. Fares A. Pharmacological and Non-pharmacological Means for Prevention of Fractures among Elderly. Int J Prev Med. 2018; 9: 78. doi: 10.4103/ijpvm.IJPVMJ14J8
  3. Compston J., Cooper A., Cooper C. et al. UK clinical guideline for the prevention and treatment of osteoporosis. Arch Osteoporos. 2017; 12 (1): 43. doi: 10.1007/s11657-017-0324-5
  4. Wang J., Wang X., Fang Z. et al. The effect of FRAX on the prediction of osteoporotic fractures in urban middle-aged and elderly healthy Chinese adults. Clinics (Sao Paulo). 2017; 72: 289-93. doi: 10.6061/clinics/2017(05)06
  5. Булгакова С. В., Романчук Н. П. Половые гормоны и когнитивные функции: современные данные. Бюллетень науки и практики. 2020; 6 (3): 69-95 doi: 10.33619/2414-2948/52/09
  6. Булгакова С.В., Романчук П.И., Тренева Е.В. Инсулин, головной мозг, болезнь Альцгеймера: новые данные. Бюллетень науки и практики. 2020; 6 (3): 96-126 doi: 10.33619/2414-2948/52/10
  7. Avenell A., Mak J.C., O’Connell D. Vitamin D and vitamin D analogues for preventing fractures in post-menopausal women and older men. Cochrane Database Syst Rev. 2014; 4: CD000227. doi: 10.1002/14651858.CD000227.pub4
  8. Avenell A., Mak J.C., O’Connell D. Vitamin D and vitamin D analogues for preventing fractures in post-menopausal women and older men. Cochrane Database Syst Rev. 2014; 4: CD000227. doi: 10.1002/14651858.CD000227.pub4
  9. Tang B.M., Eslick G.D., Nowson C. et al. Use of calcium or calcium in combination with vitamin D supplementation to prevent fractures and bone loss in people aged 50 years and older: A meta-analysis. Lancet. 2007; 370: 657-66. doi: 10.1016/S0140-6736(07)61342-7
  10. Harvey N.C., Biver E., Kaufman J.M. et al. The role of calcium supplementation in healthy musculoskeletal ageing: An expert consensus meeting of the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) and the International Foundation for Osteoporosis (IOF). Osteoporos Int. 2017; 28: 44762. doi: 10.1007/s00198-016-3773-6
  11. Byun J.H., Jang S., Lee S. et al. The efficacy of bisphosphonates for prevention of osteoporotic fracture: An update meta-analysis. J Bone Metab. 2017; 24: 37-49. doi: 10.11005/jbm.2017.24.1.37
  12. Zhou J., Wang T., Zhao X. et al. Comparative efficacy of bisphosphonates to prevent fracture in men with osteoporosis: A systematic review with network meta-analyses. Rheumatol Ther. 2016; 3: 117-28. doi: 10.1007/s40744-016-0030-6
  13. Wells G.A., Cranney A., Peterson J. et al. Alendronate for theprimary and secondaryprevention of osteoporotic fractures in postmenopausal women. Cochrane Database Syst Rev. 2008; 1: CD001155. doi: 10.1002/14651858. CD001155.pub2
  14. Chesnut C.H., Silverman S., Andriano K. et al. PROOF Study Group. A randomized trial of nasal spray salmon calcitonin in postmenopausal women with established osteoporosis: The prevent recurrence of osteoporotic fractures study. Am J Med. 2000; 109: 267-76. doi: 10.1016/s0002-9343(00)00490-3
  15. Wells G., Chernoff J., Gilligan J.P. et al. Does salmon calcitonin cause cancer? A review and meta-analysis. Osteoporos Int. 2016; 27: 13-9. doi: 10.1007/s00198-015-3339-z
  16. Torgerson D.J., Bell-Syer S.E. Hormone replacement therapy and prevention of non-vertebral fractures: A meta-analysis of randomized trials. JAMA. 2001; 285: 2891-7. doi: 10.1001/jama.285.22.2891
  17. Torgerson D.J., Bell-Syer S.E. Hormone replacement therapy and prevention of vertebral fractures: A meta-analysis of randomized trials. BMC Musculoskelet Disord. 2001; 2: 7. doi: 10.1186/1471-2474-2-7
  18. Fujiwara S., Hamaya E., Sato M. et al. Systematic review of raloxifene in postmenopausal Japanese women with osteoporosis or low bone mass (osteopenia). Clin Interv Aging. 2014; 9: 1879-93. doi: 10.2147/CIA.S70307
  19. Cummings S.R., Ensrud K., Delmas P.D. et al. Lasofoxifene in postmenopausal women with osteoporosis. N Engl J Med. 2010; 362: 686-96. doi: 10.1056/NEJMoa0808692
  20. Palacios S., Silverman S.L., de Villiers T.J. et al. Bazedoxifene Study Group. A 7-year randomized, placebo-controlled trial assessing the long-term efficacy and safety of bazedoxifene in postmenopausal women with osteoporosis: Effects on bone density and fracture. Menopause. 2015; 22: 806-13. doi: 10.1097/GME.0000000000000419
  21. Santesso N., Carrasco-Labra A., Brignardello-Petersen R. Hip protectors for preventing hip fractures in older people. Cochrane Database Syst Rev. 2014; 3: CD001255. doi: 10.1002/14651858.CD001255.pub5
  22. Булгакова С.В. Ранняя диагностика и лечебно-профилактические мероприятия у лиц старших возрастных групп для предотвращения остеопоротических переломов. Дис.. д-ра мед. наук. Самара, 2011; 401 с.
  23. Kujala U.M., Kaprio J., Kannus P. et al. Physical activity and osteoporotic hip fracture risk in men. Arch Intern Med. 2000; 160: 705-8. DOI: 10.1001/ archinte.160.5.705
  24. Cadore E.L., Rodriguez-Maflas L., Sinclair A. et al. Effects of different exercise interventions on risk of falls, gait ability, and balance in physically frail older adults: A systematic review. Rejuvenation Res. 2013; 16: 105-14. doi: 10.1089/rej.2012.1397
  25. Bauman A., Merom D., Bull F.C. et al. Updating the Evidence for physical activity: summative reviews of the epidemiological evidence, prevalence, and interventions to promote «active aging». Gerontologist. 2016; 56 (Suppl. 2): S268-80. doi: 10.1093/geront/gnw031
  26. Fiatarone M.A., O’Neill E.F., Ryan N.D. et al. Exercise training and nutritional supplementation for physical frailty in very elderly people. N Engl J Med. 1994; 330 (25): 1769-75. doi: 10.1056/NEJM199406233302501
  27. Lustosa L.P., Silva J.P., Coelho F.M. et al. Impact of resistance exercise program on functional capacity and muscular strength of knee extensor in pre-frail community-dwelling older women: A randomized crossover trial. Rev Bras Fisioter. 2011; 15: 318-24.
  28. Luo S.Y., Li Y., Luo H. et al. Increased intake of vegetables, but not fruits, may be associated with reduced risk of hip fracture: A meta-analysis. Sci Rep. 2016; 6: 19783. The practice (implementation). doi: 10.1038/srep19783
  29. Hernandez-Avila M., Colditz G.A., Stampfer M.J. et al. Caffeine, moderate alcohol intake, and risk of fractures of the hip and forearm in middle-aged women. Am J Clin Nutr. 1991; 54: 157-63. doi: 10.1093/ajcn/54.1.157
  30. Wu Z.J., Zhao P., Liu B. et al. Effect of cigarette smoking on risk of hip fracture in men: A meta-analysis of 14 prospective cohort studies. PLoS One. 2016; 30: 11. doi: 10.1371/journal.pone.0168990
  31. Rosen T., Mack K.A., Noonan R.K. Slipping and tripping: Fall injuries in adults associated with rugs and carpets. J Inj Violence Res. 2013; 5: 61-9. doi: 10.5249/jivr.v5i1.177
  32. Hill A.M., Francis-Coad J., Haines T.P. et al. «My independent streak may get in the way»: How older adults respond to falls prevention education in hospital. BMJ Open. 2016; 6: e012363. http://dx.doi.org/10.1136/bmjopen-2016-012363
  33. Никитин О.Л., Романчук П.И., Булгакова С.В. и др. Способ увеличения минеральной плотности костной ткани. Патент РФ на изобретение № 2481815 от 20.05.13

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 2020 Russkiy Vrach Publishing House

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies