CURRENT POSSIBILITIES OF ANTI-INFLAMMATORY THERAPY IN PULMONOLOGY


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Abstract

The paper gives updates on a basically new direction in anti-inflammatory therapy with the phosphodiesterase 4 inhibitor roflumilast in patients with chronic obstructive pulmonary disease. It describes the mechanisms of action of the drug and indications for its use. The results of clinical trials and the possibility of using roflumilast for other lung diseases are described.

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About the authors

E. Shmelev

Central Research Institute of Tuberculosis, Russian Academy of Medical Sciences, Moscow

Email: eishmelev@mail.ru
Department of Pulmonology

N. Shmelev

Central Research Institute of Tuberculosis, Russian Academy of Medical Sciences, Moscow

Department of Pulmonology

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