NEW INHALED GLUCOCORTICOSTEROIDS FOR ASTMA

Abstract

Moscow Inhaled glucocorticosteroids (ICS) are the therapy basis for persistent asthma of any degree for the long-term control of inflammatory processes. Ciclesonide (Alvesco) is a new ICS for Russian practice is a pro-drug that is activated by the lung esterases and characterized by high anti-inflammatory properties and excellent safety profile because of low oral bioavailability, rapid elimination, high plasma protein binding. The drug affects the whole bronchial tree due to small inhaled particles.