ANTIOXIDANTS IN THE TREATMENT PROGRAM FOR POLYMORBID PATIENTS WITH METABOLIC SYNDROME


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Abstract

Using the data of a review of the medical research literature and their own results of the examination and treatment of patients with a body mass index of ≥2 5 kg/m 2 as the basis, the authors show the negative role of oxidative stress in forming insulin resistance (IR) in early metabolic syndrome (MS). The combination treatment of 54 patients with MS incorporated the antioxidants: 60 mg coenzyme Q 10 + 9 mg vitamin E daily. The study has shown that there is a close correlation between the levels of IR and the markers of oxidative stress. The restored capacity of the antioxidant system (coenzyme Q 10 + vitamin E) promotes the effective recovery of sensitivity of insulin receptors to insulin in the early phases of obesity.

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About the authors

A. Shilov

I.M. Sechenov First Moscow State Medical University

Email: melnik.m.v.@gmail.com
Professor MD

A. Abdullayeva

I.M. Sechenov First Moscow State Medical University

Email: melnik.m.v.@gmail.com

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