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Vol 23, No 7 (2012)
- Year: 2012
- Articles: 22
- URL: https://journals.eco-vector.com/0236-3054/issue/view/5914
Articles
2-8
THE MOST IMPORTANT PROBLEMS OF THE PATHOMORPHOGENESIS AND TREATMENT OF NONALCOHOLIC FATTY LIVER DISEASE IN PATIENTS WITH DIABETES MELLITUS
Abstract
The paper summarizes data on the most basic features of the pathomorphogenesis of nonalcoholic fatty liver disease in patients with diabetes mellitus (DM). The author provides his view of the possibilities of current hepatoprotective therapy for fatty hepatosis and steatohepatitis in DM. There is evidence that there is a need for the combined use of hepatoprotective drugs, prominent among which are thioctic (а-lipoic) acid preparations in combination with other medicaments.
Vrach. 2012;23(7):8-11
8-11
ANGIOTENSIN-CONVERTING ENZYME INHIBITORS IN MYOCARDIAL INFARCTION: RESULTS OF THE SMILE STUDY PROJECT
Abstract
The long-term SMILE study project using zofenopril has demonstrated that it is expedient and safe to early use the drug in hemodynamically stable patients with anterior myocardial infarction receiving no thrombolytic therapy and provided evidence that the specific features of individual angiotensin-converting enzyme inhibitors, which are associated with their chemicopharmacological properties, are of clinical value.
Vrach. 2012;23(7):11-15
11-15
DIAGNOSIS AND TREATMENT OF CHOLESTEROL-INDUCED RENAL CYST
Abstract
The described case illustrates partial nephrectomy for a space-occupying lesion that is suspicious for a tumor. Preoperative computer 3D modeling enables the information on the structure of the mass and the specific features of renal blood supply to be detailed.
Vrach. 2012;23(7):16-19
16-19
Giperfosfatemiya pri khronicheskoy bolezni pochek: sovremennaya strategiya korrektsii
Abstract
Рассматриваются механизмы нарушения минерального гомеостаза у пациентов с хронической болезнью почек (ХБП). Показано, что ранний и эффективный контроль минерально-костного метаболизма как на додиализной стадии, так и при лечении диализом - это ключ к успешному управлению ХБП.
Vrach. 2012;23(7):19-23
19-23
24-28
MAGNESIUM DEFICIENCY AND CARDIOVASCULAR DISEASES
Abstract
The paper describes the physiological mechanisms of magnesium involvement in the function of different human body systems at the level of a cell and subcellular structures. Magnesium deficiency, the incidence of which in clinical practice is as high as 70% and which appears as cardiovascular, cerebral, visceral, and muscular-tetanic syndromes, shows a clinical diversity. The pathophysiological mechanisms responsible for the implication of magnesium deficiency in the formation of insulin resistance (IR) as a key component of metabolic syndrome (MS) are discussed in detail. The authors present the results of combination treatment incorporating magnesium preparations (Magnerot 3 g/day) in 69 patients with MS. They also give the data of an analysis of the time course of changes in IR values, carbohydrate and lipid metabolic parameters, and blood rheological spectra.
Vrach. 2012;23(7):28-33
28-33
34-39
39-43
THE If-CHANNEL INHIBITOR IVABRADINE IN COMBINATION THERAPY FOR PATIENTS WITH STABLE FORMS OF CORONARY HEART DISEASE
Abstract
Forty-three patients (27 men and 16 women; mean age 63.24 years) with coronary heart disease (CHD) were examined to assess the clinical and pharmacoeconomic aspects of the use of the If-channel inhibitor ivabradine as part of combination therapy from the data of ECG monitoring, treadmill test, and quality of life (QL) questionnaires. Ivabradine produces anti-ischemic activity, increases the volume and time of fulfilled exercise, reduces heart rate, and improves QL in patients with CHD and stable angina on exertion. The combination therapy using ivabradine is economically more advantageous than the standard therapy without this drug.
Vrach. 2012;23(7):44-48
44-48
ANTIOXIDANTS IN THE TREATMENT PROGRAM FOR POLYMORBID PATIENTS WITH METABOLIC SYNDROME
Abstract
Using the data of a review of the medical research literature and their own results of the examination and treatment of patients with a body mass index of ≥2 5 kg/m 2 as the basis, the authors show the negative role of oxidative stress in forming insulin resistance (IR) in early metabolic syndrome (MS). The combination treatment of 54 patients with MS incorporated the antioxidants: 60 mg coenzyme Q 10 + 9 mg vitamin E daily. The study has shown that there is a close correlation between the levels of IR and the markers of oxidative stress. The restored capacity of the antioxidant system (coenzyme Q 10 + vitamin E) promotes the effective recovery of sensitivity of insulin receptors to insulin in the early phases of obesity.
Vrach. 2012;23(7):49-52
49-52
Diabeticheskaya polineyropatiya: ot prognozirovaniya riska razvitiya k patogeneticheskomu lecheniyu
Abstract
ВОЗ определяет ситуацию с сахарным диабетом (СД) как эпидемию неинфекционного заболевания. В настоящее время в мире насчитывается 130 млн больных СД и каждые 25 лет их число удваивается. В статье обсуждается проблема диабетической полинейропатии у больных СД типа 2 (СД2). Обследованы 130 пациентов с СД2 без признаков полинейропатии. При наблюдении в течение 3 лет у 47% больных развилась полинейропатия. Проведен дискриминантный анализ, выявлены прогностически значимые факторы риска, выведена формула прогноза развития заболевания.
Vrach. 2012;23(7):53-56
53-56
57-59
59-62
EFFECT OF SULPIRIDE ON THE STATUS OF PATIENTS WITH BILIARY DYSFUNCTIONS
Abstract
It is expedient to evaluate systemic and segmental autonomic tone in biliary dysfunctions, by us-ing the standard CYTO autonomic test. The antidepressant and anxiolytic sulpiride (Prosulpin) enhances quality of life for patients and normalizes an imbalance in the autonomic nervous sys-tem.
Vrach. 2012;23(7):63-65
63-65
66-68
69-71
COMPLIANCE AS A GUARANTEE OF EFFECTIVE TREATMENT FOR TINEA PEDIS
Abstract
The paper gives data on the epidemiology and etiology of tinea pedis. It shows that it is necessary to take into account compliance as an important factor for the effective treatment of tinea pedis. The fact that 1% film-forming terbinafine solution might be used once provided a high compliance in its treatment. The novel formulation 1% film-forming Lamisil® UNO. even though it is used once. is as effective as Fungoterbine and surpasses it in some parameters/
Vrach. 2012;23(7):72-75
72-75
SMOKING AND RESPIRATORY ABNORMALITIES IN PATIENTS WITH PANIC DISORDER
Abstract
All our examined smoking patients with respiratory panic disorders had comorbid bronchopulmonary diseases and 75% had their family history. The latter is a basis for the vulnerability of the respiratory system and smoking is a factor that shows evidence of this vulnerability with higher levels of anxiety.
Vrach. 2012;23(7):76-78
76-78
RECURRENT CHOLEDOCHOLITHIASIS: PREVENTION AND TREATMENT
Abstract
The analysis of 110 patients with recurrent choledocholithiasis (CL) admitted for treatment in 2006-2011 has revealed the changes in the biliary ducts and major duodenal papilla, which are predisposing to their recurrence, as well as the causes of recurrent CL after endoscopic papilla sphincterotomy.
Vrach. 2012;23(7):79-81
79-81
82-85
85-88