TREATMENT OF DEPRESSION ASSOCIATED WITH CEREBROVASCULAR DISEASE (ACCORDING TO THE DATA OF THE RESONANCE RUSSIAN MULTICENTER NATURALISTIC STUDY)


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Abstract

Eighty-eight patients with depression and comorbid cerebrovascular disease were treated with Valdoxan (25-50 mg/day) in the Resonance Russian multicenter naturalistic study. Following 6-week therapy, depressive symptomatology was relieved in the vast majority (82.35%) of patients. 17-item Hamilton Depression Rating Scale (HAMD-17) scores decreased from 15.8±3.6 to 5.0±2.7 (p<0.00001). There was also a reduction in the intractable symptoms of depression (fatigability, low work efficiency, dyssomnia) and their negative impact on patient functioning.

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About the authors

O. Vorobyeva

I.M. Sechenov First Moscow State Medical University

Email: oworobeva@mail.ru
Professor MD

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