EXTRAESOPHAGEAL MANIFESTATIONS AND THEIR EARLY SYMPTOMATIC THERAPY IN ELDERLY PATIENTS WITH GASTROESOPHAGEAL REFLUX DISEASE
- Authors: Onuchina E.1, Brikova S.2, Tsukanov V.3
-
Affiliations:
- Irkutsk State Medical Academy of Postgraduate Education
- War Veterans Hospital
- Research Institute of Medical Problems of the North, Siberian Branch, Russian Academy of Medical Sciences
- Issue: Vol 25, No 3 (2014)
- Pages: 73-77
- Section: Articles
- URL: https://journals.eco-vector.com/0236-3054/article/view/115950
- ID: 115950
Cite item
Open Access
Access granted
Abstract
Extraesophageal syndromes are more characteristic for elderly patients with gastroesophageal reflux disease than for maturity-age patients (58.5 and 24.7% of cases, respectively; p<0.001) and present mainly in the elderly (67.9%) with the concurrence of 2 more or forms, more commonly with a combination of bronchopulmonary and otorhinolaryngopharyngeal syndromes. The abilities of sodium alginate to reduce the rate of the latter and its relief time with the better tolerability are higher than in antacids.
Full Text
About the authors
E. Onuchina
Irkutsk State Medical Academy of Postgraduate Education
Email: elonu@mail.ru
MD
S. Brikova
War Veterans HospitalProfessor
V. Tsukanov
Research Institute of Medical Problems of the North, Siberian Branch, Russian Academy of Medical SciencesMD
References
- Капралов Н.В., Шоломицкая И.А., Гриншпан Д.Д. и др. Исследование in vitro кислотонейтрализующей эффективности антацидных препаратов // Экспер. и клин. гастроэнтерол. - 2008; 3: 44-8.
- Онучина Е.В. Клинические проявления, факторы риска и эффективность лечения гастроэзофагеальной рефлюксной болезни у лиц пожилого возраста. Автореф. дис..д-ра мед. наук. Красноярск, 2011; с. 45.
- Янова О.Б., Березина О.И., Ким В.А. Эффективность нового альгинат-антацидного препарата в устранении постпрандиального рефлюкса // Лечащий врач. - 2013; 4: 74-8.
- Bardan E., Kern M., Arndorfer R. et al. Effect of aging on bolus kinematics during the pharyngeal phase of swallowing // Am. J. Physiol. Gastrointest. Liver Physiol. - 2006; 290: 458-65.
- El-Serag H., Sweet S., Winchester C. et al. Update on the epidemiology of gastro-oesophageal reflux disease: a systematic review // Gut. - 2013; Jul 13. Epub. ahead of print.
- Farrokhi F, Vaezi M. Extra-esophageal manifestations of gastroesophageal reflux // Oral Dis. - 2007; 13: 349-59.
- Kahrilas P., Sifrim D. High-resolution manometry and impedance-pH/ manometry: valuable tools in clinical and investigational esophagology // Gastroenterology. - 2008; 135: 756-69.
- Kwiatek M., Roman S., Fareeduddin A. et al. An alginate-antacid formulation (Gaviscon Double Action Liquid) can eliminate or displace the postprandial 'acid pocket' in symptomatic GERD patients // Aliment. Pharmacol. Ther. - 2011; 34: 59-66.
- Lien H., Chang C., Yeh H. et al. Increasing prevalence of erosive esophagitis among Taiwanese aged 40 years and above: a comparison between two time periods // J. Clin. Gastroenterol. - 2009; 43: 926-32.
- Lundell L., Dent J., Bennet J. Endoscopic assessment of oesophagitis clinical and fuctional correlates and futher validation of Los Angeles classification // Gut. - 1999; 45: 72-180.
- Qua C., Wong C., Gopala K. et al. Gastro-oesophageal reflux disease in chronic laryngitis: prevalence and response to acid-suppressive therapy // Aliment. Pharmacol. Ther. - 2007; 25: 287-95.
- Richter J. The many manifestations of gastroesophageal reflux disease: presentation, evaluation, and treatment // Gastroenterol. Clin. North. Am. - 2007; 36: 577-99.
- Spechler S., Sharma P., Souza R. et al.American Gastroenterological Association technical review on the management of Barrett's esophagus // Gastroenterology. - 2011; 140: 18-52.
- Sweis R., Kaufman E., Anggiansah A. et al. Post-prandial reflux suppression by a raft-forming alginate (Gaviscon Advance) compared to a simple antacid documented by magnetic resonance imaging and pH-impedance monitoring: mechanistic assessment in healthy volunteers and randomised, controlled, double-blind study in reflux patients // Aliment. Pharmacol Ther. - 2013; 37: 1093-102.
- Vakil N., van Zanten S., Kahrilas P. et al. The Monreal Definition and Classification of gastroesophageal reflux disease: a global evidence-based consensus // Am. J. Gastroenterology. - 2006; 101: 1900-20.
Supplementary files
