Vol 25, No 3 (2014)

Chronic lumbosacral radiculopathy is an occupational disease associated with long (at least 10-year) systemic static muscle tension, forced position of the trunk or limbs, considerable physical strain, forced posture, frequent deep torso bends at work, prolonged sitting or standing in a fixed working posture, and an inconvenient fixed working posture. The clinical and diagnostic features of chronic lumbosacral radiculopathy and the characteristics of pharmacotherapy are described.

The paper considers the clinical situations in which the entire small bowel (SB) has to be examined most frequently; it presents the evolution of enteroscopy techniques that can make a lifetime analysis of the internal structure of the longest part of the human body, as well as its associated problems. Endoscopic techniques for diagnosing SB diseases, such as video capsule and balloon-assisted enteroscopy, indications for and contraindications to their use, their importance for clinical practice and their effectiveness are depicted in detail.

Numerous controlled trials have demonstrated that ACE inhibitors are highly effective in reducing the cardiovascular risk in the treatment of patients with hypertension and coronary heart disease (CHD). The benefits of Prestarium A are the stabilization of its antihypertensive effect during 24 hours, including morning hours when a rapid elevation of blood pressure and high circadian frequency of ischemic episodes double the risk of complications in these categories of patients, as well as high tissue selectivity and good tolerability, which enables its recommendation for the treatment of patients with hypertension and CHD.

Along with the high anti-ischemic and anti-anginal efficacies of ivabradine, a radionuclide study first established its positive effect on systemic microcirculatory parameters and myocardial perfusion.

Examination of vascular wall rigidity revealed a significant increase in pulse wave propagation velocity (PWPV) and total peripheral vascular resistance in hypertensive patients with persistent atrial fibrillation (AF) versus in those without cardiac arrhythmia. There was a strong direct relationship between PWPV and left ventricular anteroposterior size in hypertensive patients with AF (r = 0.74; p < 0.05).

Cardiac resynchronization therapy (CRT) is a unique treatment for heart failure (HF) with augmented QRS; in this regard, it seems urgent to find new criteria for the prediction of a CRT super-response. While searching for these criteria, a variety of functional parameters may be put in the forefront depending on selected patient groups and used diagnostic techniques. However, the functional criteria are reversible in the vast majority of cases if HF is successfully treated. But cardiosclerosis is irreversible. Scintigraphic methods are shown to play a role in evaluating both myocardial functional parameters and cardiosclerosis. The results of the authors’ trials and clinical examples are given.

It is important to use technologies ensuring careful tissue coagulation in the treatment of benign ovarian tumors in reproductive-aged women. One of such technologies is a PlasmaJet system using argon as a source of plasma generation.

A clinical and immunological study of 132 women of reproductive age with mycoplasma infection of the lower reproductive tract. Using Tiloroneimmunomodulator in adjuvant therapy of mycoplasma infection of the lower genital tract contributes to the normalization of the clinical picture and redress the imbalance microbiocenosis cervix and vagina, identified prior to initiating therapy.

Extraesophageal syndromes are more characteristic for elderly patients with gastroesophageal reflux disease than for maturity-age patients (58.5 and 24.7% of cases, respectively; p<0.001) and present mainly in the elderly (67.9%) with the concurrence of 2 more or forms, more commonly with a combination of bronchopulmonary and otorhinolaryngopharyngeal syndromes. The abilities of sodium alginate to reduce the rate of the latter and its relief time with the better tolerability are higher than in antacids.

The paper considers the measures to prevent a water transmission route for acute enteric pathogens, which encompass centralized purification, disinfection of community water supply, its microbiological control, and improvement of the sanitation of water-supply pipeline networks.

Determination of a total cardiovascular risk in the staff of a large industrial enterprise makes it possible to evaluate the efficiency of mass medical examination and to reveal the factors preventing its qualitative performance.